Tag Archives: mesothelioma therapy

Mesothelioma and SS1P Therapy – Some Promise

Delivering a continuous dose of a new immunotoxin therapy, SS1P, is safe and shows some effectiveness against mesothelioma and other mesothelin-positive cancers. However, the drug doesn’t appear to be any more effective when given by continuous infusion than in several intermittent doses, according to a recent study published in the journal, Clinical Cancer Research. Some types of cancer, including mesothelioma, ovarian, and squamous cell cancers, display a protein called mesothelin in larger-than-normal amounts. Researchers are using this unique characteristic to develop new treatments for these cancers. One potential new treatment, called SS1P, is an immunotoxin—an antibody attached to a toxic substance that binds to and kills mesothelin-positive cancer cells like mesothelioma. “SS1P contains an antibody fragment which binds to mesothelin … Continue reading Mesothelioma and SS1P Therapy – Some Promise »

Promising New Target for Mesothelioma Therapy

Mesothelin, a protein found on the surface of cells, may be a promising new target for treating mesothelioma, as well as several other types of cancers, according to a recent study in the journal, Molecular Cancer Therapeutics. This protein might also help doctors diagnose certain cancers. The reason why mesothelin has captured researchers’ attention as a potential therapeutic target has to do with the way it is distributed in the body. In healthy people, mesothelin is only found in small amounts in cells lining the lungs, abdominal cavity, and heart. However, this protein is produced in higher amounts by mesothelioma, ovarian, and pancreatic cancer cells. To attack these cancers, researchers are looking at using specialized antibodies (a type of immune … Continue reading Promising New Target for Mesothelioma Therapy »