Survival:11.2 months
Toxicity Grade:4
Treatments:Chemotherapy
Drugs:Gemzar
Platinol
Country:Australia
City/State/Province:Nedlands, WA
Hospital:Sir Charles Gairdner Hospital
Journal:Link
Date:8/2002
Description:
Patients: This Phase II study involved 53 patients with malignant pleural mesothelioma; 45 men and 8 women. The median age was 63 years.

Treatment: The treatment consisted of two chemotherapy drugs; cisplatin (platinol) and gemcitabine (gemzar).

Toxicity: Grade 3-4 toxicities included hematologic, diarrhea, infection, neurotoxicity, vomiting, and nausea.

Results: Median survival was 11.2 months.

Support: The study was supported in part by Eli Lilly. This company markets gemzar.

Correspondence: M.J. Byrne, MD