Researchers Name Six Top Mesothelioma Survival Factors

Certain factors lead to longer mesothelioma survival

Researchers at the University of Pittsburgh have named what they say are the top six mesothelioma survival factors. According to their new study, patients with one or more of these factors tend to have better mesothelioma treatment outcomes and live longer. Malignant mesothelioma – also called asbestos cancer – is one of the deadliest forms of cancer. It starts on internal membranes and spreads quickly. There is no cure and the disease is very hard to slow down. Many mesothelioma patients die within 12 to 18 months. But there are cases of much longer mesothelioma survival. Some patients have even lived for decades after mesothelioma treatment. The Pittsburgh researchers wanted to find the mesothelioma survival factors shared by the longest … Continue reading Researchers Name Six Top Mesothelioma Survival Factors »

Combination Therapy with Mesothelioma Surgery Leads to Longer Survival

Mesothelioma surgery patient with nurse

A new study finds almost a quarter of people who had combination therapy with mesothelioma surgery were still alive five years later. The study was published in the European Journal of Cardio-Thoracic Surgery. Researchers at University Hospitals KU Leuven in Belgium studied nearly 200 mesothelioma patients from 2003 to 2014. Many people do not live beyond about 18 months after a mesothelioma diagnosis. But the Belgian team says, for the right patients, there is a way to improve the odds. They say combination therapy with radical mesothelioma surgery offers a 1 in 4 chance of surviving for 5 years or more. Two Types of Mesothelioma Surgery There are two major schools of thought about mesothelioma surgery. Some surgeons say it … Continue reading Combination Therapy with Mesothelioma Surgery Leads to Longer Survival »

Survival After Mesothelioma Surgery Could Rise with Immunotherapy Spray

improving survival after mesothelioma surgery

A spray-on immune booster may one day improve survival after mesothelioma surgery. UCLA scientists tested the biodegradable spray gel in mice with advanced melanoma. They found that it stopped cancer recurrence after surgery in about half of the lab animals tested. “Around 90 percent of people with cancerous tumors end up dying because of tumor recurrence or metastasis,” says lead investigator Zhen Gu. “Being able to develop something that helps lower this risk for this to occur and has low toxicity is especially gratifying.” Gu is a professor of bioengineering and a member of the UCLA Jonsson Comprehensive Cancer Center where the spray was developed. Survival After Mesothelioma Surgery Survival after mesothelioma surgery or any other kind of cancer operation … Continue reading Survival After Mesothelioma Surgery Could Rise with Immunotherapy Spray »

Mesothelioma Surgery PD Comparison

operation for mesothelioma

Lung-sparing surgery is another name for pleurectomy/decortication (PD). In PD, surgeons take out as much mesothelioma cancer as they can without taking out one of the lungs. The other main type of mesothelioma surgery is called EPP (extrapleural pneumonectomy). In that surgery, doctors do take out a lung when they take out the mesothelioma tumor. Some studies say patients who have PD surgery live longer than people who have EPP. They may also have fewer problems after surgery. What is the New Clinical Trial? Researchers in Belgium and The Netherlands are running a test called EORTC 1205. EORTC 1205 is a clinical trial. Clinical trials test new drugs or treatments to see how well they work in people. Right now, … Continue reading Mesothelioma Surgery PD Comparison »

Meta-Analysis Finds Lung-Sparing Surgery the Best Option for Most Mesothelioma Patients

There is now more evidence to support the growing number of experts who favor lung-sparing P/D surgery over radical extrapleural pneumonectomy (EPP) for the treatment of malignant pleural mesothelioma. There has been an ongoing debate within the surgical community over which procedure carries the most benefit with the least risk. The late David Sugarbaker, MD, of Baylor St. Luke’s Medical Center in Houston was a pioneer of the EPP procedure, which involves removing not only the diseased pleural lining where mesothelioma tumors grow, but also the nearest lung, most of the diaphragm, the pericardium, and other at-risk tissues. But it turns out that, although Sugarbaker and his team were able to show a mesothelioma survival benefit with EPP, their results, … Continue reading Meta-Analysis Finds Lung-Sparing Surgery the Best Option for Most Mesothelioma Patients »

Mesothelioma Surgery and the Threat of Opioid Addiction

A new study of opioid addiction among lung cancer patients may have implications for pleural mesothelioma patients who are considering surgery. The study, published this month in JAMA Oncology, finds that patients treated with more invasive surgical techniques are more likely to become chronic opioid users than those who have less invasive surgery. Opioids Are ‘Standard of Care’ for Lung Surgery Patients Researchers at Mount Sinai Medical Center in New York studied the cases of nearly 4,000  people from the SEER Medicare database who had some type of surgery for non-small cell lung cancer, a type of cancer that shares many commonalities with the lung-related asbestos cancer, pleural mesothelioma. Some of the lung cancer patients studied underwent open thoracic surgery while others … Continue reading Mesothelioma Surgery and the Threat of Opioid Addiction »

Surgery May Offer Survival Advantage for Rare Mesothelioma Subtypes

People with the most dangerous subtypes of malignant pleural mesothelioma may live longer if they undergo surgery. In an article in the Annals of Thoracic Surgery, University of Arizona researchers say cancer-directed surgery can lengthen survival in people with sarcomatoid and biphasic mesothelioma, two of the hardest cancers to treat. Multiple studies have suggested that there is a survival benefit from surgery in people with epithelioid mesothelioma, the most common subtype. But, the evidence is much more scanty for people with either sarcomatoid or biphasic mesothelioma, both of which are associated with a worse mesothelioma prognosis  and shorter overall survival. Now, the Tucson-based research team says surgery aimed at removing the cancer (rather than just alleviating symptoms) can help these mesothelioma … Continue reading Surgery May Offer Survival Advantage for Rare Mesothelioma Subtypes »

Short Term Mesothelioma Survival Better with Conservative Surgery

Researchers at the Icahn School of Medicine at Mount Sinai have added their voices to the ongoing debate over the best type of surgery for malignant pleural mesothelioma. After a meta-analysis of 30-day mortality among 500 mesothelioma patients, the group has come down on the side of pleurectomy decortication (PD), the more conservative — and less risky — of the two major types of mesothelioma surgery. Mesothelioma Surgery: EPP vs. P/D Pleural mesothelioma, also referred to as asbestos cancer, is notoriously difficult to treat. Successful mesothelioma treatment usually involves a combination of therapies, such as Alimta (pemetrexed), radiotherapy, and curative surgery in patients who are healthy enough to undergo it. (Surgery is currently only recommended for patients with epithelioid mesothelioma, … Continue reading Short Term Mesothelioma Survival Better with Conservative Surgery »

New Study Points to Benefits of IMRT for Mesothelioma Treatment

There is more evidence that mesothelioma patients who have lung sparing surgery can live longer if it’s followed up with highly targeted radiation therapy. In the first study to come out of Israel on the subject, a team of oncologists, pulmonologists, radiation oncologists, and thoracic surgeons at Rabin Medicine Center in Petah Tikva say intensity modulated radiation therapy (IMRT) is safe and effective for slowing down the growth of pleural mesothelioma tumors. The Challenge of Radiotherapy for Mesothelioma The irregularity of malignant mesothelioma tumors makes them difficult to treat with standard external beam radiotherapy without damaging healthy tissue and causing serious side effects. This is particularly problematic in patients who still have both lungs, either because they were not good … Continue reading New Study Points to Benefits of IMRT for Mesothelioma Treatment »

Muscle Loss May Predict Peritoneal Mesothelioma Survival

Age-related muscle loss appears to be an independent predictor of peritoneal mesothelioma survival after surgery. The news might help patients and doctors make better treatment decisions. Researchers at the Lyon-Sud Hospital Center in Lyon say they have found a connection between sarcopenia—muscle loss associated with aging—and how long people with peritoneal mesothelioma (or another abdominal condition called pseudomyxoma peritonei) survive after cytoreductive surgery. The bottom line: The less muscle loss, the longer a mesothelioma patient is likely to survive. CRS/HIPEC Surgery for Mesothelioma Cancer Both peritoneal mesothelioma and pseudomyxoma peritonei (PMP) are cancers that grow in the abdomen. Like other types of malignant mesothelioma, peritoneal mesothelioma is associated with exposure to asbestos. It is typically a fast-growing cancer for which … Continue reading Muscle Loss May Predict Peritoneal Mesothelioma Survival »

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