A new predictive model may make it easier for cancer doctors to choose the best mesothelioma surgery for each pleural mesothelioma patient. There are two major surgical approaches for pleural mesothelioma. One involves removal of a lung and the other does not. Right now, the choice about which surgery to have is based on patient demographics, symptoms, and lab values. Which surgery is most common at the institution may also play a role. Many surgeons have strong opinions about which is the best mesothelioma surgery. But Harvard researchers say the new predictive model they tested is a better way to stratify mesothelioma patients. Their study suggests that this approach may lead to better treatment outcomes and more accurate clinical trials. … Continue reading New Test May Help Doctors Choose the Best Mesothelioma Surgery
Having adjuvant radiotherapy after surgery may not help mesothelioma patients live any longer according to researchers at Duke and Stanford Universities. Researchers used a database of pleural mesothelioma patients from Duke and a national registry to conduct the analysis. They compared the outcomes of patients who had radiation after surgery (adjuvant radiotherapy) with the outcomes of those who did not. While radiotherapy may help reduce mesothelioma symptoms for some patients, the results of the study suggest that it is unlikely to extend survival. Radiation for Mesothelioma and Its Symptoms Radiotherapy is a mainstay of cancer therapy for certain kinds of cancer. But the irregular shape and aggressive nature of mesothelioma tumors makes them less than ideal for radiation treatment. Pleural … Continue reading Adjuvant Radiotherapy May Not Lengthen Mesothelioma Survival, Study Shows
Non-incisional pleurectomy/decortication could be the wave of the future for malignant mesothelioma treatment. Environmental health experts in Japan say it is possible to remove the diseased pleural lining in a person with mesothelioma without making incisions that could spread their cancer. The procedure is called non-incisional pleurectomy/decortication. It is a new way to perform mesothelioma surgery that may be safer, faster, and more effective. Japanese researchers recently published a report on their experience with the technique. The report appears in the newest issue of General Thoracic and Cardiovascular Surgery. Surgical Treatment of Pleural Mesothelioma Pleural mesothelioma is the most common form of asbestos cancer. It occurs on the pleura, a thin membrane surrounding the lungs. From there, pleural mesothelioma can … Continue reading Non-Incisional Pleurectomy/Decortication for Mesothelioma
The best mesothelioma surgery is the one the patient can tolerate with the fewest serious side effects. That’s according to a new study from MD Anderson researchers. Their goal was to help settle the ongoing debate over which type of pleural mesothelioma surgery is most effective. Both EPP and P/D surgery are major operations. But one causes much more serious side effects than the other. So how do doctors and patients decide on the best mesothelioma surgery for their case? The new research suggests there may not be a definitive answer. Debate Over the Best Mesothelioma Surgery Pleural mesothelioma is an asbestos-linked cancer of the membrane around the lungs. During EPP (extrapleural pneumonectomy) surgery, doctors remove this membrane, any other … Continue reading Study Asks What is the Best Mesothelioma Surgery?
Japanese researchers say P/D surgery for mesothelioma improves quality of life for most patients, even if their lung function gets worse. Doctors at the Hyogo College of Medicine tracked the cases of forty-five patients who had P/D surgery for mesothelioma between 2014 and 2018. Lung function tests showed most pleural mesothelioma patients could not breathe as well after surgery as they did before. Their energy, vitality, and social functioning also decreased. But patients reported better mental health after surgery and significantly less pain. The researchers conclude that quality of life after P/D surgery for mesothelioma may have less to do with breathing than previously thought. What is P/D Surgery for Mesothelioma? Pleural mesothelioma tumors grow on the pleura, a thin … Continue reading P/D Surgery for Mesothelioma Improves Quality of Life Regardless of Lung Function
A mesothelioma treatment called NIPEC may help people with peritoneal mesothelioma live longer than expected. In some cases, much longer. A recent study of 74 peritoneal mesothelioma patients showed a combination of cytoreductive surgery (CRS), HIPEC, and NIPEC works better than CRS/HIPEC alone. The study comes from one of the country’s foremost medical authorities on peritoneal mesothelioma. Dr. Paul Sugarbaker runs the Peritoneal Surface Malignancy Program at Washington Cancer Institute in Washington, DC. Last year, Dr. Sugarbaker released results of a small study on NIPEC treatment for mesothelioma. Although that study included only six patients, the results were impressive enough to warrant further study. This year’s larger NIPEC study is even more promising for people fighting mesothelioma. Similarities and DIfferences … Continue reading NIPEC Treatment: Is This the Key to Long-Term Mesothelioma Survival?
The two major types of mesothelioma surgeries carry similar risk of death, according to a new study from cancer researchers in Japan. One surgery involves removing the diseased pleural lining and one of the lungs. The other surgery removes many of the same tissues but leaves the lungs intact. Surgeons around the world are divided as to which of these mesothelioma surgeries is best. Mesothelioma patients have more complications with lung-removing surgery. But some studies suggest it could lead to longer survival. The 4-year Japanese study included more than 600 patients. It suggests that the likelihood of dying is similar with either of these mesothelioma surgeries. Surgical Treatment of Pleural Mesothelioma Pleural mesothelioma is the most common type of asbestos … Continue reading Mesothelioma Surgeries Carry Similar Mortality Risk, Study Finds
A new French study contains some good news for people considering the CRS/HIPEC procedure for peritoneal mesothelioma. The CRS/HIPEC procedure combines surgical resection with localized chemotherapy. Its aim is to remove or destroy as many mesothelioma cells as possible in the abdomen. French researchers studied the evolution of the procedure over time. They discovered that it has improved. As a result, people with peritoneal cancers like malignant mesothelioma are living longer. Cytoreductive Surgery for Mesothelioma Peritoneal mesothelioma causes tumors on the peritoneal membrane that lines the abdomen. Like other forms of mesothelioma, the cause is usually asbestos exposure. Cytoreductive surgery (CRS) is an operation to remove tumors from the abdomen. Mesothelioma tumors may be confined to the peritoneal membrane, or … Continue reading CRS/HIPEC Procedure Has Improved Over Time, Study Finds
A new study from the Icahn School of Medicine at Mount Sinai in New York suggests that minimally invasive surgery for mesothelioma is a “viable alternative” to open-chest procedures. Both of the two main surgical procedures for pleural mesothelioma are usually done through a large incision in the chest. Both procedures also carry a high risk of post-surgical complications. But the New York researchers found that minimally invasive surgery for mesothelioma may produce fewer serious problems in the short-term. It may also give mesothelioma patients a better quality of life after surgery. Surgical Treatment of Pleural Mesothelioma Pleural mesothelioma tumors occur on tissue that surrounds the lungs. These tumors tend to spread out across the tissue in irregular shapes. Their … Continue reading Minimally Invasive Surgery for Mesothelioma is “Viable Alternative” to Standard Approaches
Pleural biopsy is not perfect when it comes to telling the difference between the three mesothelioma subtypes. But misclassification could lead to shorter survival. That is the conclusion reached by top mesothelioma researchers in Brescia, Italy. They compared autopsy records from 134 Italian mesothelioma patients. The patients were either shipyard workers or their spouses. The researchers found that the mesothelioma subtypes identified from biopsy tissue were incorrect a large percent of the time. Misclassification matters because it impacts which mesothelioma treatments doctors choose. The Three Mesothelioma Subtypes Pleural mesothelioma is an aggressive malignancy on the lung lining. It is caused by exposure to asbestos. Mesothelioma cells fall into three mesothelioma subtypes based on certain cellular characteristics. Pleural mesothelioma is notoriously … Continue reading Mesothelioma Subtypes Often Misclassified by Biopsy