Researchers Argue Against Surgery for Mesothelioma

surgery for mesothelioma

A pair of California surgeons say surgery for mesothelioma is rarely worthwhile. They point to what they say are flawed studies on surgical treatment. One trial they believe was well-conducted seems to show reduced mesothelioma survival after surgery. Writing in the journal Translational Lung Cancer Research, the doctors argue that most patients should choose non-surgical treatment for mesothelioma.  Some Background on Surgery for Mesothelioma Pleural mesothelioma is a cancer of the lining around the lungs. It is an aggressive cancer with no known cure. There are two primary approaches to surgery for mesothelioma. Both types are controversial and the subject of much debate among surgeons.  Extrapleural pneumonectomy (EPP) is a surgical approach that involves removing the pleural membrane, one lung, … Continue reading Researchers Argue Against Surgery for Mesothelioma »

Surgery Extends Survival for Patients with Pleural Mesothelioma

patients with pleural mesothelioma

Patients with pleural mesothelioma who choose to have surgery live longer than those who do not. This applies no matter which kind of surgery they have.  That is the conclusion of a Mexican study published in the Annals of Oncology. Doctors with the country’s National Institute for Respiratory Diseases conducted the study. It included 122 pleural mesothelioma patients.  The researchers analyzed a wide range of variables like age, sex, asbestos exposure, and overall health. They discovered that the decision to have surgery was one of the most important survival factors in patients with pleural mesothelioma. Treatment Options for Patients with Pleural Mesothelioma Pleural mesothelioma is an aggressive cancer with no known cure. It usually occurs in people who have been … Continue reading Surgery Extends Survival for Patients with Pleural Mesothelioma »

Predicting Unresectable Mesothelioma Prior to Surgery

unresectable mesothelioma

Cancer researchers at Baylor have found an effective way to identify certain cases of unresectable mesothelioma without making an incision. They focused on a common reason a surgeon might decide not to operate, even after the patient is on the table. The condition, called DCWI, is hard to identify without opening the patient up.  But the Baylor team says there is a non-invasive way to identify DCWI and predict cases of unresectable mesothelioma. If it works, it could save patients the pain of surgery. It could also save lives by allowing doctors to start other mesothelioma treatments sooner.  Diffuse Chest Wall Invasion in Mesothelioma Diffuse chest wall invasion (DCWI) is a condition that can make it impossible to perform effective … Continue reading Predicting Unresectable Mesothelioma Prior to Surgery »

Deep Vein Thrombosis After Pleurectomy for Mesothelioma

deep vein thrombosis after pleurectomy

The authors of a new study on deep vein thrombosis after pleurectomy say mesothelioma patients may be at special risk. They say routine screening after pleural mesothelioma surgery could save lives. The study comes from Brigham and Women’s Hospital, a leader in cancer research. The research team followed a series of mesothelioma patients who agreed to be part of a DVT surveillance program.  Nearly 30 percent of the patients experienced deep vein thrombosis after pleurectomy. A third of those patients had no symptoms. Understanding DVT  Deep vein thrombosis or DVT is when a blood clot forms in the deep veins of the arm, leg, or groin. If the clot goes unnoticed, it can travel through the circulation and lodge in … Continue reading Deep Vein Thrombosis After Pleurectomy for Mesothelioma »

Radical Surgery for Peritoneal Mesothelioma Boosts Survival

radical surgery for peritoneal mesothelioma

Patients who have radical surgery for peritoneal mesothelioma live longer than those who have non-surgical treatments.  That is the conclusion of a team of Virginia researchers. The study is based on peritoneal mesothelioma cases in the National Cancer Database. It spans more than a decade and includes over 2,000 patients.  Not everyone is a candidate for radical surgery for peritoneal mesothelioma. But the research shows that those who have surgery live an average of five times longer than those who do not.  Surgical Treatment of Peritoneal Mesothelioma Peritoneal mesothelioma is sometimes called diffuse malignant peritoneal mesothelioma. It is an aggressive cancer in the abdomen. It grows on the membrane around organs. Because mesothelioma tumors lie so close to these organs, … Continue reading Radical Surgery for Peritoneal Mesothelioma Boosts Survival »

Invasiveness of Peritoneal Mesothelioma: MRI Beats CT for Assessment

invasvieness of peritoneal mesothelioma

New research shows MRI beats CT when it comes to measuring the invasiveness of peritoneal mesothelioma. Scientists from several of the top US cancer centers ran the study. It included nearly 500 mesothelioma patients and appears in the journal Clinical Colorectal Cancer.  The study shows that the invasiveness of peritoneal mesothelioma is more visible on MRI than it is on CT. The news could make a difference in how doctors plan peritoneal mesothelioma treatment.  Peritoneal Cancer Index and Mesothelioma Peritoneal mesothelioma cancer grows on the peritoneal membrane lining the abdomen. Like all forms of mesothelioma, it usually comes from exposure to asbestos. Peritoneal mesothelioma accounts for about a fifth of all mesothelioma cases.  Doctors assess the invasiveness of peritoneal mesothelioma … Continue reading Invasiveness of Peritoneal Mesothelioma: MRI Beats CT for Assessment »

Mesothelioma Recurrence After PD Surgery

mesothelioma recurrence after PD surgery

A new study finds that mesothelioma recurrence after PD surgery is common but most patients still live for more than a year afterwards. More than a third were still alive three years after recurrence. The study included 90 Japanese patients with malignant pleural mesothelioma.  Those who lived for at least a year without mesothelioma recurrence after PD surgery had the best chance of longer term survival. A good performance status and undergoing additional treatment were also key to better outcomes.  Understanding Pleurectomy with Decortication (PD) Surgery Pleural mesothelioma is a virulent cancer that occurs on the membrane around the lungs. There is no cure for mesothelioma. Even with the best treatment, the cancer usually comes back. The goal of most … Continue reading Mesothelioma Recurrence After PD Surgery »

Peritoneal Mesothelioma Surgery with HIPEC Can Trigger Blood Cell Problems

peritoneal mesothelioma surgery with HIPEC

More than half of patients who have peritoneal mesothelioma surgery with HIPEC develop problems with their blood cells afterward. That’s the finding of a team of cancer researchers from Singapore.  The group analyzed 15 years worth of data on peritoneal mesothelioma surgery outcomes. They found that, even though the procedure saves lives, it can be risky.  Older patients and those who had prior chemotherapy were most likely to develop hematological toxicities after peritoneal mesothelioma surgery.  Hematological Toxicities and Mesothelioma Treatment Hematological toxicities are problems with the cells that make up the blood. This can include white blood cells, red blood cells, platelets, and proteins involved in bleeding and clotting.  Several drugs that kill mesothelioma cells can cause blood cell problems. … Continue reading Peritoneal Mesothelioma Surgery with HIPEC Can Trigger Blood Cell Problems »

Repeated Mesothelioma Surgeries Credited with Japanese Man’s Survival

repeated mesothelioma surgeries

Can repeated mesothelioma surgeries extend peritoneal mesothelioma survival? A new case report out of Japan suggests the answer may be yes.  The article recounts the case of a patient with peritoneal mesothelioma. Each time surgeons removed a mesothelioma tumor, a new one would occur in a different location.  The man had four separate mesothelioma surgeries over the course of five years.  Repeated mesothelioma surgeries are not the norm. But this treatment approach may be the reason for the man’s unusually long mesothelioma survival.  Surgical Treatment of Peritoneal Mesothelioma Peritoneal mesothelioma accounts for about 20 percent of mesothelioma cases in the US each year. It occurs on the membrane that surrounds the abdominal organs. Because it sits so close to these … Continue reading Repeated Mesothelioma Surgeries Credited with Japanese Man’s Survival »

Mesothelioma Clinical Trials: Study Highlights Challenges for Patients

mesothelioma clinical trials

A new UK study points to some of the potential challenges and benefits for patients involved in mesothelioma clinical trials.  Researchers at three teaching hospitals in England interviewed mesothelioma patients who took part in the Mesothelioma and Radical Surgery (MARS 2) trial.  The trial compared outcomes in people who had a combination of surgery and chemotherapy with those who only had chemotherapy. The findings show that not all aspects of mesothelioma clinical trials are positive for patients.  A Study Within a Study Pleural mesothelioma is a fast-growing cancer that starts on the lining around the lungs. Asbestos exposure is usually the cause. With standard cancer treatments, most mesothelioma patients face a poor prognosis. Mesothelioma often leads to death within a … Continue reading Mesothelioma Clinical Trials: Study Highlights Challenges for Patients »

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