CRS/HIPEC Treatment Helps Double Survival Among Swedish Mesothelioma Patients

CRS/HIPEC Treatment

A new report suggests that CRS/HIPEC treatment has helped to double the odds of surviving peritoneal mesothelioma in Sweden.  Researchers collected data from the Swedish National Cancer Registry. A total of 102 peritoneal mesothelioma cases were included from two separate 5-year time periods. The report shows that, since CRS/HIPEC treatment was introduced in Sweden, overall survival of peritoneal mesothelioma increased from 7 to 15 months. At 5 years, twice as many peritoneal mesothelioma patients were still alive. The researchers conclude that this is likely due, at least in part, to CRS/HIPEC treatment.  Surviving Peritoneal Mesothelioma Peritoneal mesothelioma is an aggressive cancer that starts on the membrane lining the abdomen. It is almost always caused by accidental swallowing of microscopic asbestos … Continue reading CRS/HIPEC Treatment Helps Double Survival Among Swedish Mesothelioma Patients »

Unresectable Peritoneal Mesothelioma Becomes Operable After Bi-Directional Chemotherapy

French researchers have successfully operated on a man with unresectable peritoneal mesothelioma after treating him with bi-directional chemotherapy. Chemotherapy is the most common treatment for unresectable peritoneal mesothelioma. Most mesothelioma patients have chemotherapy by IV infusion. But some cancer centers now offer another chemotherapy delivery method. Intraperitoneal chemotherapy bypasses the bloodstream. It lets doctors put higher doses of cancer-killing medicine at the site of a tumor. The French team combined the two types of chemotherapy in one patient. It shrunk the patient’s unresectable peritoneal mesothelioma tumor enough to perform surgery.  Two Types of Mesothelioma Chemotherapy With IV chemotherapy, medicine travels to the tumor through the bloodstream. It is one way of treating unresectable peritoneal mesothelioma. One drawback of IV chemotherapy … Continue reading Unresectable Peritoneal Mesothelioma Becomes Operable After Bi-Directional Chemotherapy »

Minimally Invasive Lymph Node Staging May Prevent Unnecessary Mesothelioma Surgery

lymph node staging for mesothelioma

A minimally invasive procedure for lymph node staging may help some pleural mesothelioma patients avoid the pain and risk of surgery. That is the conclusion of a recent study on endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA).  EBUS-TBNA is a minimally invasive method for testing the lymph nodes deep in the chest (mediastinal lymph nodes). If lymph node staging shows evidence of pleural mesothelioma, surgery is less likely to be effective.  Mediastinal Lymph Node Staging and Mesothelioma Pleural mesothelioma is a rare cancer that starts on the membrane around the lungs. It can spread to the lungs and other organs and is usually fatal.  The mediastinal lymph nodes are located in the area between the lungs. When the body is fighting … Continue reading Minimally Invasive Lymph Node Staging May Prevent Unnecessary Mesothelioma Surgery »

Large Study Finds Treatment Combination Leads to Long-Term Mesothelioma Survival

long-term mesothelioma survival

There is more evidence that surgery and intraperitoneal chemotherapy can lead to long-term mesothelioma survival. The news comes from an Australian study of more than 1,200 cancer patients. The study finds that one in five peritoneal mesothelioma patients who had this treatment combination were still alive 10 years later.  Peritoneal Cancer Survival with Surgery  Peritoneal cancers occur on the lining of the abdomen. Peritoneal mesothelioma starts on this peritoneal membrane. Some other peritoneal cancers start elsewhere in the body and spread to the peritoneum. The new Australian study analyzed the cases of peritoneal cancer patients who had cytoreductive surgery between 1996 and 2018. Cytoreductive surgery aims to remove as much of the cancer as possible. Past studies have found that … Continue reading Large Study Finds Treatment Combination Leads to Long-Term Mesothelioma Survival »

HITHOC Treatment Deemed Safe for Some Pleural Mesothelioma Patients

HITHOC treatment for mesothelioma

German doctors testing the HITHOC treatment for pleural mesothelioma say it is a “safe therapeutic option”. The key to success is careful patient selection. Pleural mesothelioma is a rare cancer linked to asbestos. Tumors grow on the membrane that surrounds the lungs. Doctors have not yet found a cure for mesothelioma.  HITHOC treatment involves rinsing heated chemotherapy drugs through the chest after mesothelioma surgery. The new study suggests that this advanced approach may help certain mesothelioma patients live longer.  Understanding Pleural Mesothelioma Tumors To understand how HITHOC treatment works, it is important to understand how and where mesothelioma tumors grow.  Pleural mesothelioma tumors start on the lining around the lungs called the pleura. As tumors grow, the pleura thickens and … Continue reading HITHOC Treatment Deemed Safe for Some Pleural Mesothelioma Patients »

PIPAC May Make More Patients Candidates for Mesothelioma Surgery

candidates for mesothelioma surgery

Researchers in France have come up with a way to turn some people with inoperable peritoneal mesothelioma into good candidates for mesothelioma surgery.  They are using a new technique to spray chemotherapy drugs directly onto peritoneal tumors in order to shrink them.  In some cases, the technique shrunk mesothelioma tumors enough that they could be surgically removed with the CRS/HIPEC procedure.  What Makes a Good Candidate for Mesothelioma Surgery A number of factors influence whether patients are good candidates for mesothelioma surgery. Patients have to be in otherwise reasonably good health so that their body can handle the surgery. It is also critical that their mesothelioma not be so widespread in their abdomen that it would be impossible for surgeons … Continue reading PIPAC May Make More Patients Candidates for Mesothelioma Surgery »

Gel-Based Mesothelioma Treatment: A Novel Approach to Pleural Mesothelioma

gel-based mesothelioma treatment

Swiss scientists are developing a novel gel-based mesothelioma treatment for people with pleural disease. Early studies suggest it may be a safer way to deliver cancer-fighting drugs with fewer side effects. The gel-based mesothelioma treatment combines the chemotherapy drug cisplatin with a natural “glue” called fibrin. When the gel is applied during surgery, it can keep fighting tumors for months. Why Develop a Gel-Based Treatment? Cisplatin is a platinum-based drug. Together with pemetrexed (Alimta), it is one of the most common chemotherapy drugs for mesothelioma. In the past decade, doctors came up with a way to increase the effectiveness of cisplatin in people with peritoneal mesothelioma. These patients get chemotherapy the usual way. But they also get a rinse of … Continue reading Gel-Based Mesothelioma Treatment: A Novel Approach to Pleural Mesothelioma »

Mesothelioma Quality of Life Improves After Surgery

mesothelioma quality of life

New research confirms that surgery followed by HIPEC improves mesothelioma quality of life for people with peritoneal disease. Every mesothelioma surgery carries risks and can cause serious side effects. These problems often have a negative impact on mesothelioma quality of life in the short term. But researchers at Wake Forest University say cytoreductive surgery followed by intraperitoneal chemotherapy (HIPEC) boosts life quality for most mesothelioma patients over time. Evolving Management of Peritoneal Mesothelioma Malignant mesothelioma is a fast-growing cancer with a very low cure rate. Peritoneal mesothelioma accounts for about a fifth of all mesothelioma cases. With peritoneal mesothelioma, tumors start on the membrane that surrounds the abdominal organs and can spread to other parts of the body. Fatigue, pain, … Continue reading Mesothelioma Quality of Life Improves After Surgery »

Post-Surgery Mesothelioma Treatment: Key to Survival for Elderly Patients?

post-surgery mesothelioma treatment

Ability to tolerate post-surgery mesothelioma treatment is one of the most important survival factors for elderly mesothelioma patients. That is according to a new article in the Annals of Surgical Oncology. The article says surgery alone will not help older mesothelioma patients live longer. It says they need post-surgery mesothelioma treatments like chemotherapy to get the survival benefits of surgery. But, as a recent mesothelioma study demonstrated, surgery can weaken some older patients. These patients may then be too fragile to have other treatments that could extend their lives. Few Older Patients Have Post-Surgery Mesothelioma Treatment As Surviving Mesothelioma recently reported, many mesothelioma patients over 80 get no treatment at all. In more than 60 percent of cases, mesothelioma doctors … Continue reading Post-Surgery Mesothelioma Treatment: Key to Survival for Elderly Patients? »

Many Elderly Mesothelioma Patients Get No Treatment

elderly mesothelioma patients

The majority of elderly mesothelioma patients are observed rather than treated and this can have a negative impact on their survival. That is the finding of a new study published in the Annals of Surgical Oncology. The study included more than 4,500 mesothelioma patients. Less than a quarter of these patients received any treatment for their mesothelioma. As a result, most of these patients lived less than six months. Treatment Options for Elderly Mesothelioma Patients Exposure to asbestos causes pleural mesothelioma. It can take decades after exposure for mesothelioma symptoms to occur. The median age for a malignant pleural mesothelioma diagnosis is 72. The older a patient is at diagnosis, the more likely they are to have other health problems. … Continue reading Many Elderly Mesothelioma Patients Get No Treatment »

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