Complications After PD Surgery for Mesothelioma

Complications After PD Surgery

Durable air leak is one of the most common complications after PD surgery for pleural mesothelioma, according to the authors of a new study. People with overall better health are less likely than others to experience the problem.  Air leaks happen when inhaled air does not stay in the alveoli in the lungs. Instead, it leaks into the area around the lungs. This can cause breathing problems and put pressure on the heart. Too much leaked air can even collapse a lung. A new Japanese study found that more than half of mesothelioma patients analyzed experienced serious complications after PD surgery. One in three patients suffered from air leak for more than ten days.  Pleurectomy/Decortication for Mesothelioma Pleural mesothelioma is … Continue reading Complications After PD Surgery for Mesothelioma »

Peritoneal Mesothelioma Survival Not Shortened by Organ Resection

peritoneal mesothelioma survival

A new study finds that organ resection during CRS/HIPEC surgery does not shorten peritoneal mesothelioma survival and may even help prolong it.  The new research included 174 peritoneal mesothelioma patients from cancer centers across the country. These patients had cytoreductive surgery followed by heated intraperitoneal chemotherapy (CRS/HIPEC).  About half of the patients also had at least one organ removed to help prevent mesothelioma recurrence. The goal of the new study was to determine what impact, if any, this practice has on peritoneal mesothelioma survival. The answer appears to be, not much.  CRS/HIPEC and Peritoneal Mesothelioma Survival About 20 percent of mesothelioma patients have the peritoneal variety. This type of mesothelioma occurs on the lining of the abdomen and can easily … Continue reading Peritoneal Mesothelioma Survival Not Shortened by Organ Resection »

Lung-Sparing Surgery for Mesothelioma Superior to EPP, Study Says

Lung-Sparing Mesothelioma Surgery

A team of Japanese researchers have added their voices to the ongoing debate over lung-sparing surgery for mesothelioma. The researchers analyzed multiple studies on the different kinds of surgery for mesothelioma. The studies included more than 2,600 mesothelioma patients.  After a careful review of the data, the Japanese team concluded that lung-sparing surgery for mesothelioma is almost always better than removing a lung. Mesothelioma patients who had this type of surgery had much fewer complications. They lived just as long as those who had more radical mesothelioma surgery.  Radical and Conservative Mesothelioma Surgery Malignant mesothelioma is a membrane cancer caused by asbestos exposure. It usually occurs in the membrane around the lungs. About 20 percent of cases occur on the … Continue reading Lung-Sparing Surgery for Mesothelioma Superior to EPP, Study Says »

Long Term Peritoneal Mesothelioma Survival with NIPEC

Long Term Peritoneal Mesothelioma Survival

A new report suggests that long term peritoneal mesothelioma survival may be possible with a treatment called NIPEC and the drug paclitaxel.  NIPEC stands for normothermic intraperitoneal chemotherapy. It is similar to the heated chemotherapy that many peritoneal mesothelioma patients now get. But NIPEC is delivered through a catheter over time and at room temperature.  The new article details the long term peritoneal mesothelioma survival of six patients on NIPEC with paclitaxel. It comes from one the nation’s leading experts in this form of mesothelioma, Paul Sugarbaker, MD.  Even though the sample size is small, Dr. Sugarbaker says the results are impressive enough to warrant further study.  HIPEC and Mesothelioma Treatment Peritoneal mesothelioma accounts for about 20 percent of mesothelioma … Continue reading Long Term Peritoneal Mesothelioma Survival with NIPEC »

Black Mesothelioma Patients Less Likely to Receive Surgery

black mesothelioma patients

Black mesothelioma patients are less likely to receive potentially-life saving surgery than white patients, even though they have worse short-term mortality.   That is the finding of a new study published in the Journal of Immigrant and Minority Health.  Mount Sinai researchers used data from the National Cancer Institute to compare mesothelioma treatment trends among 2550 patients.  They concluded that both white and black mesothelioma patients live longer with surgery, but white patients tend to get the most benefit. Surgical Options for Malignant Mesothelioma Malignant mesothelioma is a membrane cancer. It can occur in different places in the body. The type of treatment varies depending on where the cancer occurs. For mesothelioma in the abdomen (peritoneal mesothelioma), surgery with a rinse … Continue reading Black Mesothelioma Patients Less Likely to Receive Surgery »

Surgery for Peritoneal Mesothelioma Could Be Limited During Pandemic

Surgery for peritoneal mesothelioma

It may be harder this year for patients who need it to get surgery for peritoneal mesothelioma.  An international group called RENAPE keeps track of peritoneal cancers like mesothelioma. The group advises doctors on the best treatment practices. The group is advising hospitals to tighten the criteria for who can get surgery for peritoneal mesothelioma during the pandemic.  “The Covid-19 pandemic is profoundly changing the organization of healthcare access,” say French doctors writing about the RENAPE recommendations. “This is particularly so for peritoneal neoplastic diseases, for which curative treatment mobilizes substantial personnel, operating room and intensive care resources.” Mesothelioma Treatment Options Mesothelioma is a rare cancer associated with asbestos exposure. About a fifth of all mesothelioma cases are the peritoneal … Continue reading Surgery for Peritoneal Mesothelioma Could Be Limited During Pandemic »

Radiotherapy Before Mesothelioma Surgery May Not Be Worth the Risk

Radiotherapy before mesothelioma surgery

Cancer doctors at Mayo Clinic say they do not plan to start routinely performing radiotherapy before mesothelioma surgery. The idea is based on a radiation protocol called SMART. The team monitored how well the SMART protocol worked among their pleural mesothelioma patients over a one year period.  The Mayo doctors acknowledged that radiotherapy before mesothelioma surgery can sometimes improve outcomes. But too many of their patients developed serious complications. In a recently-published article, the team concludes that SMART may not be worth the risk for most patients.  The SMART Way to Treat Mesothelioma? Pleural mesothelioma grows on the membrane that surrounds the lungs. Mesothelioma tumors lie close to the lungs and heart and may spread to one or both lungs. … Continue reading Radiotherapy Before Mesothelioma Surgery May Not Be Worth the Risk »

Researchers Argue Against Surgery for Mesothelioma

surgery for mesothelioma

A pair of California surgeons say surgery for mesothelioma is rarely worthwhile. They point to what they say are flawed studies on surgical treatment. One trial they believe was well-conducted seems to show reduced mesothelioma survival after surgery. Writing in the journal Translational Lung Cancer Research, the doctors argue that most patients should choose non-surgical treatment for mesothelioma.  Some Background on Surgery for Mesothelioma Pleural mesothelioma is a cancer of the lining around the lungs. It is an aggressive cancer with no known cure. There are two primary approaches to surgery for mesothelioma. Both types are controversial and the subject of much debate among surgeons.  Extrapleural pneumonectomy (EPP) is a surgical approach that involves removing the pleural membrane, one lung, … Continue reading Researchers Argue Against Surgery for Mesothelioma »

Surgery Extends Survival for Patients with Pleural Mesothelioma

patients with pleural mesothelioma

Patients with pleural mesothelioma who choose to have surgery live longer than those who do not. This applies no matter which kind of surgery they have.  That is the conclusion of a Mexican study published in the Annals of Oncology. Doctors with the country’s National Institute for Respiratory Diseases conducted the study. It included 122 pleural mesothelioma patients.  The researchers analyzed a wide range of variables like age, sex, asbestos exposure, and overall health. They discovered that the decision to have surgery was one of the most important survival factors in patients with pleural mesothelioma. Treatment Options for Patients with Pleural Mesothelioma Pleural mesothelioma is an aggressive cancer with no known cure. It usually occurs in people who have been … Continue reading Surgery Extends Survival for Patients with Pleural Mesothelioma »

Predicting Unresectable Mesothelioma Prior to Surgery

unresectable mesothelioma

Cancer researchers at Baylor have found an effective way to identify certain cases of unresectable mesothelioma without making an incision. They focused on a common reason a surgeon might decide not to operate, even after the patient is on the table. The condition, called DCWI, is hard to identify without opening the patient up.  But the Baylor team says there is a non-invasive way to identify DCWI and predict cases of unresectable mesothelioma. If it works, it could save patients the pain of surgery. It could also save lives by allowing doctors to start other mesothelioma treatments sooner.  Diffuse Chest Wall Invasion in Mesothelioma Diffuse chest wall invasion (DCWI) is a condition that can make it impossible to perform effective … Continue reading Predicting Unresectable Mesothelioma Prior to Surgery »

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