CT Discovery May Lead to Earlier Mesothelioma Diagnosis

Detecting Mesothelioma with New CT Algorithm

Researchers in Western Australia believe they may have found a way to overcome one of the biggest challenges in the management of malignant pleural mesothelioma—making the diagnosis earlier. Malignant mesothelioma is a fast-growing cancer that starts on the membrane, or pleura, that surrounds the lungs. Because the seeds for this disease can exist for decades before symptoms develop, and because the early symptoms of mesothelioma tend to be vague and similar to those of other conditions, the so-called “asbestos cancer” often goes undetected until it is in an advanced stage. As a result, the survivability of this disease is typically very low. But scientists at the University of Western Australia in Perth say there may be a simple way to … Continue reading CT Discovery May Lead to Earlier Mesothelioma Diagnosis »

What Type of Mesothelioma Do I Have? CT May Be Able to Tell

Researchers from one of the country’s top cancer centers say it may be possible to tell what subtype of pleural mesothelioma a person has by using computed tomography (CT). Pleural mesothelioma is an aggressive lung-related cancer for which patients and their doctors must develop a treatment plan quickly to get ahead of the disease. The challenge is that, not only is mesothelioma highly resistant to standard cancer treatment, but different subtypes of mesothelioma are often managed with different drugs and therapies. The new study from Memorial Sloan Kettering Cancer Center in New York suggests that CT may offer an accurate and non-invasive way to classify mesothelioma patients which could speed the treatment planning process and lead to longer mesothelioma survival. … Continue reading What Type of Mesothelioma Do I Have? CT May Be Able to Tell »

PET Beats CT in Study of Mesothelioma Staging Tools

PET Scan

When it comes to accurately assessing the extent of an individual case of malignant pleural mesothelioma, Positron Emission Tomography (PET) may be more effective than Computed Tomography (CT). A combination of the two is even better. That conclusion comes from researchers at the University of Toronto who analyzed the cases of more than 100 mesothelioma patients being considered for multimodality therapy at Princess Margaret Cancer Centre in Toronto. Researchers compared the accuracy of PET and CT separately and together to determine how effective each was at identifying 1) the extent to which mesothelioma had spread to the lymph nodes (N stage) and 2) the number and location of metastatic mesothelioma tumors (M stage). Both N and M staging are used … Continue reading PET Beats CT in Study of Mesothelioma Staging Tools »

Mesothelioma Biomarker Test May Be Diagnostic Alternative for Frail Patients

A set of proteins found in the lung fluid of people with malignant pleural mesothelioma may offer a safer way to diagnose the asbestos cancer in frail or elderly patients. Mesothelioma is an extremely difficult cancer to diagnose. Accurate diagnosis usually requires a combination of tests including a physical exam, a thorough work history (including possible asbestos exposure), blood or lung fluid tests, imaging scans, and a biopsy. But not all mesothelioma patients are able to tolerate an invasive procedure such as a thoracoscopy to obtain a tissue sample. For these patients especially, an accurate blood or lung fluid test could be lifesaving. Protein Biomarkers for Mesothelioma Diagnosis Researchers in Japan recently evaluated the diagnostic value of two types of … Continue reading Mesothelioma Biomarker Test May Be Diagnostic Alternative for Frail Patients »

Miner Study Finds Mesothelioma Often Undiagnosed

A new study of former South African mine workers suggests that too many asbestos-related diseases may be going undiagnosed. The study conducted by researchers at the University of the Witwatersrand and the National Institute for Occupational Health in Johannesburg found that, in a cohort of 149 workers, more than half of the cases of malignant mesothelioma were missed until after the patient had died. With cases of asbestos-related lung cancer, the difference between the number of cases identified by an autopsy and the number of cases actually diagnosed in the patient’s lifetime was even more dramatic – 22 identifications on autopsy versus just 3 lung cancer diagnoses. Doctors diagnosed 52 cases of the lung-scarring disease asbestosis among the studied workers, … Continue reading Miner Study Finds Mesothelioma Often Undiagnosed »

Asbestos Found in the Gallbladders of Pleural Mesothelioma Patients

There is new evidence that asbestos fibers can make their way into the gallbladders of patients with the lung-related cancer malignant pleural mesothelioma. The finding may help explain why some of these patients also suffer from gallbladder disorders. A new study conducted in Italy and published in the Journal of Microscopy discovered microscopic fibers of the mineral asbestos when they analyzed thin sections of gallbladders from malignant pleural mesothelioma patients under an electron microscopy. Migrating Asbestos Fibers Exposure to asbestos is the primary cause of malignant mesothelioma, an aggressive cancer that starts on the membranes around the lungs, abdomen or heart. When mesothelioma grows on the pleural membrane around the lungs, it is known as pleural mesothelioma. Asbestos fibers are … Continue reading Asbestos Found in the Gallbladders of Pleural Mesothelioma Patients »

Diagnostic Accuracy of CT Limited for Pleural Mesothelioma

When it comes to diagnosing pleural mesothelioma, Scottish researchers say CT scanning is not accurate enough. Contrast-enhanced computed tomography (CT) can provide a cross-sectional image of the chest in people with suspected pleural mesothelioma. But researchers at Queen Elizabeth University Hospital in Glasgow say their tests show that CT is not sensitive enough to either confirm or rule out mesothelioma in most cases. CT Scans and Mesothelioma Diagnosis CT scanning is an imaging procedure that uses special X-ray equipment to create detailed cross-sectional images. These images are then compiled to create three-dimensional models. CT scanning is a routine part of mesothelioma diagnosis. But the new report published in the journal Lung Cancer suggests that false positive and false negative mesothelioma diagnoses … Continue reading Diagnostic Accuracy of CT Limited for Pleural Mesothelioma »

Mesothelioma Diagnosis Still a Possibility for 9/11 Survivors

Fifteen years after the 9/11 terrorist attack on the World Trade Center, some of the wounds inflicted that day have begun to heal. Unfortunately others, including many anticipated cases of malignant mesothelioma, have yet to be revealed. Malignant mesothelioma is the most deadly of several serious health conditions associated with the fibrous mineral, asbestos. It can take decades after people inadvertently inhale or swallow the fibers for them to develop symptoms of the disease. Asbestos was a popular insulator and building component additive at the time the Twin Towers were constructed. Some four hundred tons of the toxin was used in the building. When the towers came down, thousands of first responders and New Yorkers were exposed to enormous clouds of dust … Continue reading Mesothelioma Diagnosis Still a Possibility for 9/11 Survivors »

Monitoring Program Improves Mesothelioma Diagnosis

A Polish program designed to identify mesothelioma earlier in former asbestos plant workers could have implications for malignant mesothelioma patients around the world. Mesothelioma is the most deadly of a range of diseases associated with exposure to asbestos. Other illnesses linked to asbestos exposure include lung cancer, asbestosis and pleural plaques. A new report published by Poland’s Nofer Institute of Occupational Health, says a 16-year-old mesothelioma monitoring program has led to better understanding of malignant mesothelioma, improved the ability to diagnose it, and identified more cases that might have otherwise gone undetected. Mesothelioma in Asbestos Workers Although asbestos was banned in Poland in 1997, because the disease has such a long latency period, many people are still being diagnosed with mesothelioma. … Continue reading Monitoring Program Improves Mesothelioma Diagnosis »

Mesothelioma-Related Lung Fluid: Better Diagnosis with HIgh Tech Tool

Technology that integrates 18-FDG PET and CT imaging together may be a more powerful way to diagnose malignant lung fluid in people with pleural mesothelioma than either modality alone. Scientists in China did a retrospective study to compare the imaging results of people with pleural effusion from various causes, including malignant pleural mesothelioma.  The team found that the integrated PET/CT technology accurately diagnosed malignant pleural effusion better than 18FDG-PET imaging alone and much better than CT imaging. What is Malignant Pleural Effusion? Malignant pleural effusion is a condition where fluid containing cancer cells collects in the pleural space between the lungs and the chest wall. If this fluid is caused by a condition other than malignant mesothelioma or another cancer, … Continue reading Mesothelioma-Related Lung Fluid: Better Diagnosis with HIgh Tech Tool »

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