Accurate Diagnosis of Pleural Mesothelioma with History and Imaging Only

accurate diagnosis of mesothelioma

Medical history and CT imaging may be enough to make an accurate diagnosis of pleural mesothelioma, even without a biopsy. That finding comes from a team of French and Canadian researchers led by Universite Laval in Quebec.  Biopsy is usually considered critical for accurate diagnosis of pleural mesothelioma. But the French and Canadian team says imaging studies may provide enough information to make a diagnosis.  This could be especially good news for people who are not healthy enough to undergo thoracoscopy. Pleural Mesothelioma Diagnostic Procedure: First Steps Pleural mesothelioma is the most common type of mesothelioma. Mesothelioma is an aggressive cancer that grows on the membranes around internal organs.  This cancer is rare and notoriously difficult to diagnose, especially in … Continue reading Accurate Diagnosis of Pleural Mesothelioma with History and Imaging Only »

Low-Dose CT Screening May Delay Mesothelioma Deaths

low-dose ct screening for meosthelioma

The results of a long-term national study suggest that low-dose CT screening might prevent – or at least delay – deaths from pleural mesothelioma.  The National Lung Screening Trial included more than 53,000 lung cancer patients. Researchers released the first results in 2011 after more than six years of study. The recent follow-up results reflect more than 12 years of data on low-dose CT screening. They show that, in many cases, screening lung cancer patients for at least three years delayed their deaths for more than a decade.  Pleural Mesothelioma and Lung Cancer Pleural mesothelioma is not the same thing as lung cancer. Mesothelioma starts on the lining around the lungs (pleura), rather than in the lung tissue itself.  But … Continue reading Low-Dose CT Screening May Delay Mesothelioma Deaths »

Exposed to Asbestos? Lung Fluid Test May Waste Valuable Time

exposed to asbestos worker

If you have been exposed to asbestos and your doctor sees a mesothelioma tumor on your CT scan, it may be a waste of time to do a lung fluid test, too. Many different types of cancer cause excess lung fluid or pleural effusions. Looking for cancer cells in pleural effusions is one of the ways doctors test for cancers like pleural mesothelioma. This is called effusion cytology. But a new study says this test may not be very reliable for people with malignant mesothelioma. If other factors point to mesothelioma, they say it makes more sense to skip effusion cytology and go straight to a biopsy. Mesothelioma Develops in People Exposed to Asbestos Pleural mesothelioma is a type of … Continue reading Exposed to Asbestos? Lung Fluid Test May Waste Valuable Time »

Talc Pleurodesis Patients Need Alternate PET/CT Scan for Mesothelioma

PET/CT scan for mesothelioma

Certain patients may get more benefit out of an alternate type of PET/CT scan for mesothelioma. Positron emission tomography (PET) is a common tool for diagnosing mesothelioma. It is also used to monitor the effectiveness of mesothelioma treatments. Doctors often combine PET with computed tomography (CT) for an even clearer picture of mesothelioma progression. Typically, a PET/CT scan for mesothelioma involves injection of a tracer called FDG (fluorodeoxyglucose). But it turns out that PET/CT scans with this tracer do not work well for all mesothelioma patients. A new Japanese study suggests that mesothelioma patients who have had a procedure called talc pleurodesis should consider a different kind of PET/CT scan instead. How Does Talc Pleurodesis Impact PET/CT Scan for Mesothelioma? … Continue reading Talc Pleurodesis Patients Need Alternate PET/CT Scan for Mesothelioma »

CT Discovery May Lead to Earlier Mesothelioma Diagnosis

Detecting Mesothelioma with New CT Algorithm

Researchers in Western Australia believe they may have found a way to overcome one of the biggest challenges in the management of malignant pleural mesothelioma—making the diagnosis earlier. Malignant mesothelioma is a fast-growing cancer that starts on the membrane, or pleura, that surrounds the lungs. Because the seeds for this disease can exist for decades before symptoms develop, and because the early symptoms of mesothelioma tend to be vague and similar to those of other conditions, the so-called “asbestos cancer” often goes undetected until it is in an advanced stage. As a result, the survivability of this disease is typically very low. But scientists at the University of Western Australia in Perth say there may be a simple way to … Continue reading CT Discovery May Lead to Earlier Mesothelioma Diagnosis »

What Type of Mesothelioma Do I Have? CT May Be Able to Tell

Researchers from one of the country’s top cancer centers say it may be possible to tell what subtype of pleural mesothelioma a person has by using computed tomography (CT). Pleural mesothelioma is an aggressive lung-related cancer for which patients and their doctors must develop a treatment plan quickly to get ahead of the disease. The challenge is that, not only is mesothelioma highly resistant to standard cancer treatment, but different subtypes of mesothelioma are often managed with different drugs and therapies. The new study from Memorial Sloan Kettering Cancer Center in New York suggests that CT may offer an accurate and non-invasive way to classify mesothelioma patients which could speed the treatment planning process and lead to longer mesothelioma survival. … Continue reading What Type of Mesothelioma Do I Have? CT May Be Able to Tell »

PET Beats CT in Study of Mesothelioma Staging Tools

PET Scan

When it comes to accurately assessing the extent of an individual case of malignant pleural mesothelioma, Positron Emission Tomography (PET) may be more effective than Computed Tomography (CT). A combination of the two is even better. That conclusion comes from researchers at the University of Toronto who analyzed the cases of more than 100 mesothelioma patients being considered for multimodality therapy at Princess Margaret Cancer Centre in Toronto. Researchers compared the accuracy of PET and CT separately and together to determine how effective each was at identifying 1) the extent to which mesothelioma had spread to the lymph nodes (N stage) and 2) the number and location of metastatic mesothelioma tumors (M stage). Both N and M staging are used … Continue reading PET Beats CT in Study of Mesothelioma Staging Tools »

Mesothelioma Biomarker Test May Be Diagnostic Alternative for Frail Patients

A set of proteins found in the lung fluid of people with malignant pleural mesothelioma may offer a safer way to diagnose the asbestos cancer in frail or elderly patients. Mesothelioma is an extremely difficult cancer to diagnose. Accurate diagnosis usually requires a combination of tests including a physical exam, a thorough work history (including possible asbestos exposure), blood or lung fluid tests, imaging scans, and a biopsy. But not all mesothelioma patients are able to tolerate an invasive procedure such as a thoracoscopy to obtain a tissue sample. For these patients especially, an accurate blood or lung fluid test could be lifesaving. Protein Biomarkers for Mesothelioma Diagnosis Researchers in Japan recently evaluated the diagnostic value of two types of … Continue reading Mesothelioma Biomarker Test May Be Diagnostic Alternative for Frail Patients »

Miner Study Finds Mesothelioma Often Undiagnosed

A new study of former South African mine workers suggests that too many asbestos-related diseases may be going undiagnosed. The study conducted by researchers at the University of the Witwatersrand and the National Institute for Occupational Health in Johannesburg found that, in a cohort of 149 workers, more than half of the cases of malignant mesothelioma were missed until after the patient had died. With cases of asbestos-related lung cancer, the difference between the number of cases identified by an autopsy and the number of cases actually diagnosed in the patient’s lifetime was even more dramatic – 22 identifications on autopsy versus just 3 lung cancer diagnoses. Doctors diagnosed 52 cases of the lung-scarring disease asbestosis among the studied workers, … Continue reading Miner Study Finds Mesothelioma Often Undiagnosed »

Asbestos Found in the Gallbladders of Pleural Mesothelioma Patients

There is new evidence that asbestos fibers can make their way into the gallbladders of patients with the lung-related cancer malignant pleural mesothelioma. The finding may help explain why some of these patients also suffer from gallbladder disorders. A new study conducted in Italy and published in the Journal of Microscopy discovered microscopic fibers of the mineral asbestos when they analyzed thin sections of gallbladders from malignant pleural mesothelioma patients under an electron microscopy. Migrating Asbestos Fibers Exposure to asbestos is the primary cause of malignant mesothelioma, an aggressive cancer that starts on the membranes around the lungs, abdomen or heart. When mesothelioma grows on the pleural membrane around the lungs, it is known as pleural mesothelioma. Asbestos fibers are … Continue reading Asbestos Found in the Gallbladders of Pleural Mesothelioma Patients »

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