New ‘Drug Factory’ Implant Eliminates Mesothelioma in Mice

New ‘Drug Factory’ Implant Eliminates Mesothelioma in Mice

A new ‘drug factory’ implant has eliminated advanced-stage mesothelioma tumors in mice. The treatment is effective in just a few days. It works by combining a “drug factory” implant with a checkpoint inhibitor drug. The news comes from researchers at Rice University and Baylor College of Medicine. The treatment worked in 100% of the animals treated. And it shows amazing hope for the future of mesothelioma. How the Treatment Works The treatment uses tiny drug-producing beads no larger than the tip of a needle. The beads go to work next to the mesothelioma tumor. Here, they work to produce continuous, high doses of interleukin-2 (IL-2). IL-2 is a natural compound that triggers white blood cells to fight cancer. The study … Continue reading New ‘Drug Factory’ Implant Eliminates Mesothelioma in Mice »

Cost Comparison of Immunotherapy vs. Traditional Chemotherapy in Mesothelioma

Cost Comparison of Immunotherapy vs. Traditional Chemotherapy in Mesothelioma

A new study does a cost comparison of immunotherapy over traditional chemotherapy. Immunotherapy and chemotherapy are common in the first-line treatment of malignant pleural mesothelioma. The news came from Therapeutic Advances in Medical Oncology. Traditional Chemotherapy In 2004, the FDA approved pemetrexed for the treatment of malignant pleural mesothelioma. Pemetrexed is often taken together with cisplatin. It is for patients whose disease is either inoperable or who are not candidates for surgery. Pemetrexed + cisplatin/carboplatin are chemotherapy drugs. Chemotherapy is a group of toxic drugs that kill cells by damaging their DNA. They target both cancerous and healthy cells. Patients with this chemo regimen also take folic acid and vitamin B12 supplements. This helps to reduce side effects from the … Continue reading Cost Comparison of Immunotherapy vs. Traditional Chemotherapy in Mesothelioma »

Major Effect of COVID-19 on Mesothelioma Patient Survival in Italy

Major Effect of COVID-19 on Mesothelioma Patient Survival in Italy

The COVID‐19 pandemic had a major effect on some mesothelioma patients in Italy. A new study in Medical & Clinical Research shows how the pandemic harmed new diagnoses and survival. Malignant mesothelioma is one of the rarest types of cancer. Many people have never even heard of ‘asbestos cancer’ until they are diagnosed. Most do not know anyone else who has it. Social distancing to protect themselves against COVID-19 compounds the problem. The timely diagnosis of mesothelioma is important. Although it may not change the prognosis of the disease, it can help in treatment strategies. Treatment delays due to the COVID-19 pandemic had a major effect on survival rates for some patients. Survival Rate during Pandemic During the COVID-19 pandemic, … Continue reading Major Effect of COVID-19 on Mesothelioma Patient Survival in Italy »

Localized Mesothelioma Successfully Treated with Chemotherapy and Surgery

A patient with a rare, localized malignant pleural mesothelioma has been successfully treated. The patient received chemotherapy and surgery and has been disease-free for 12 months. Many believe that a localized form of pleural mesothelioma might have a better survival outlook. This is compared with patients who have the more common, diffuse variety. This latest report comes from a Japanese team of thoracic surgeons. Local vs. Diffuse Mesothelioma Malignant mesothelioma is a rare cancer affecting an estimated 2,500 Americans annually. All forms of mesothelioma have been linked to asbestos exposure. Malignant pleural mesothelioma is the most common form of malignant mesothelioma. Most pleural mesothelioma patients have a type of cancer that tends to spread quickly. It spreds across the thin membrane … Continue reading Localized Mesothelioma Successfully Treated with Chemotherapy and Surgery »

Easing the Painful Symptoms of Malignant Pleural Mesothelioma

Easing the Painful Symptoms of Malignant Pleural Mesothelioma

Malignant pleural mesothelioma is an aggressive and rare cancer. There is new hope for reducing the painful symptoms of malignant pleural mesothelioma. A new study in BMC Cancer looked at treatments and the symptom burden of malignant pleural mesothelioma in Europe. The symptoms of malignant pleural mesothelioma are very hard. But there are treatments available to improve quality of life. New data proves that chemotherapy eases mesothelioma symptoms. And it is most likely to improve and maintain health-related quality of life. The Long Journey of Mesothelioma Mesothelioma is the asbestos-caused cancer. Malignant pleural mesothelioma is the most common form of mesothelioma. It accounts for over 90,000 deaths per year globally. It takes a very long time to diagnose mesothelioma. Usually, … Continue reading Easing the Painful Symptoms of Malignant Pleural Mesothelioma »

Treatment Protocol of an 8-Year Survivor of Mesothelioma

Treatment Protocol of an 8-Year Survivor of Mesothelioma

A new article in Scholars Journal of Medical Case Reports outlines the treatment protocol of an 8-year survivor of mesothelioma. Malignant pleural mesothelioma is difficult to treat. This aggressive cancer is caused by asbestos exposure and is resistant to most standard cancer therapies, including radiotherapy. Many people diagnosed with mesothelioma die within a few months to a year. Paul Kraus is considered the longest documented survivor of mesothelioma in the world. He was diagnosed in 1997 and was given little hope of survival. Not willing to give up, he worked with a team of doctors to create his own tailored treatment protocol. This protocol included dramatic lifestyle changes, experimental therapies, dietary changes, mind-body medicine, and other modalities. Paul was fortunate. … Continue reading Treatment Protocol of an 8-Year Survivor of Mesothelioma »

New Self-Administered Inhaled Gene Therapy Linked to Mesothelioma Survival

A team of doctors in Japan have developed a new oral inhaled gene therapy for the treatment of mesothelioma. This is a new gene therapy that mesothelioma patients can self-administer, much like an asthma inhaler. There’s new evidence that therapies that prevent cancer cells from forming new blood vessels may offer a better way to approach malignant pleural mesothelioma. Gene therapy has attracted attention in recent years. A new study suggests that inhalable gene drugs are effective treatments for asbestos-induced malignant pleural mesothelioma. Gene Therapy Treatments Mesothelioma is the most deadly of several diseases caused by asbestos exposure, including lung cancer and asbestosis. Most people who develop mesothelioma live less than a year after diagnosis. It is most common in … Continue reading New Self-Administered Inhaled Gene Therapy Linked to Mesothelioma Survival »

10 New Clinical Practice Guidelines on Immunotherapy for Mesothelioma

10 New Clinical Practice Guidelines on Immunotherapy for Mesothelioma

The Society for Immunotherapy of Cancer (SITC) organized a multidisciplinary panel of experts to develop new clinical practice guidelines on the use of immunotherapy in mesothelioma treatment. Immunotherapy is a type of cancer treatment. It uses the patient’s immune system to fight cancer. Immunotherapy has changed lung cancer care in recent years. It can help some patients survive longer. There is a new type of immune treatment called Immune checkpoint inhibitors (ICIs). ICI’s are used to treat patients with mesothelioma. The use of ICIs to treat mesothelioma tumors has quickly become part of clinical practice. Immune checkpoint inhibitors block mesothelioma’s natural resistance to immune system Challenges remain on how to identify patients who might benefit from ICIs. A panel of … Continue reading 10 New Clinical Practice Guidelines on Immunotherapy for Mesothelioma »

National Institutes of Health Reports on Advances in Malignant Peritoneal Mesothelioma

National Institutes of Health Reports on Advances in Malignant Peritoneal Mesothelioma

A new article from the National Institutes of Health gives the latest advances in mesothelioma. CRS-HIPEC has offered improved survival for surgical candidates. But outcomes for inoperable malignant peritoneal mesothelioma remain poor. Advancements in technology have provided new treatment approaches. The NIH reports new clinical trials are arising and are imperative. The Numbers Behind Peritoneal Mesothelioma Peritoneal mesothelioma is caused by exposure to asbestos. It is caused by the ingestion of asbestos fibers. Those microscopic asbestos fibers become embedded in the abdomen (peritoneum). After 20 to 50 years, these fibers can cause inflammation and mutations in the healthy mesothelial cells. These mutations can cause these cells to become cancerous thus, forming tumors in the peritoneum. Patients diagnosed with peritoneal mesothelioma … Continue reading National Institutes of Health Reports on Advances in Malignant Peritoneal Mesothelioma »

Encouragement for Mesothelioma Patients with Indwelling Pleural Catheters (IPCs)

Encouragement for Mesothelioma Patients with Indwelling Pleural Catheters (IPCs)

Mesothelioma patients with an (IPC) for pleural effusion are encouraged. The device is now recommended and widely used as a first-line treatment. In fact, IPCs may even eventually facilitate new kinds of mesothelioma treatments. In a study on how IPCs compare with other treatment options, researchers examined the benefits and drawbacks of IPCs. The study included patients with a broad range of cancer, including malignant mesothelioma. The rest had either breast cancer or lung cancer. IPCs for Pleural Effusion The buildup of excess lung fluid is known as pleural effusion. It is one of the most life-limiting and bothersome side effects of mesothelioma. As mesothelioma tumors grow, the body often reacts by filling the pleural space around the lungs with … Continue reading Encouragement for Mesothelioma Patients with Indwelling Pleural Catheters (IPCs) »

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