A newly-published report suggests that artificial intelligence (AI) might help pathologists predict recurrence of mesothelioma. The report focuses on technology developed by the RIKEN Center for Advanced Intelligence Project (AIP) in Japan. The Center claims the computer program taught itself to recognize key features in images of cancer. Some of the features were ones that even pathologists did not know about. The findings suggest that AI and pathologists could predict recurrence of mesothelioma better than pathologists alone. How AI Might Predict Recurrence of Mesothelioma A computer program usually has to be “taught” to perform a certain task. But this limits how far the learning can go. Instead of “teaching” it about cancer, researchers let the RIKEN technology learn on its … Continue reading It May Be Possible to Predict Recurrence of Mesothelioma with Help from AI
A common antibiotic may improve mesothelioma patients’ response to radiation therapy. The concept is based on new research from the Perelman School of Medicine at the University of Pennsylvania. Doctors there gave the antibiotic vancomycin to genetically modified mice. The mice had been modified to develop cancer. Mice that got the antibiotic had a better response to radiation therapy than untreated mice. The effect applied not only to the treated tumor but also to tumors outside the treatment area. A heightened response to radiation therapy could be good news for patients with metastatic mesothelioma. Understanding Cancer Response to Radiation Therapy Radiation therapy combats malignant mesothelioma by disrupting the DNA inside cancer cells. Mesothelioma tumors are irregularly-shaped which can make them … Continue reading Antibiotic May Boost Response to Radiation Therapy for Mesothelioma
Newly diagnosed pleural mesothelioma patients may be at higher risk for depression and that could be impacting their outcomes. A new report finds that people diagnosed with advanced lung cancers are more likely to suffer from depression. Pleural mesothelioma is a form of lung cancer. This risk for depression appears to have an impact on patients’ quality of life, their pain, and even the number of complications they experience. Assessing the Risk for Depression in Cancer Patients Researchers at Ohio State University directed the study. It included 186 patients with Stage IV non-small-cell lung cancer. The patients had not yet started their cancer treatment. Although pleural mesothelioma is not the same as non-small cell lung cancer, the two diseases share … Continue reading Is There a Risk for Depression Among Pleural Mesothelioma Patients?
A distinguished team of scientists are calling for a national mesothelioma registry they say could improve outcomes. If the registry collects and provides the right information, they say it could even help prevent future mesothelioma cases. Experts from the CDC, the National Institute for Occupational Safety and Health (NIOSH), and several top US cancer centers participated in a workshop on the topic. The Mesothelioma Applied Research Foundation convened the workshop. The group says existing tumor registries at some cancer centers are not as useful as a national mesothelioma registry. But coordinating a national registry will require government support. What is a Mesothelioma Registry? Malignant mesothelioma is a rare cancer which makes it hard to study. A national mesothelioma registry is … Continue reading Mesothelioma Registry Could Improve Outcomes, Prevent Future Cases
An often-ignored set of lymph nodes behind the ribs could help make pleural mesothelioma staging more accurate and valuable. Staging is the process of determining how advanced a patient’s cancer is. It involves looking at various different factors and assigning a rating between 0 and 4. A higher stage indicates more extensive cancer. A new report suggests that the posterior intercostal lymph nodes behind the ribs play a more important role in pleural mesothelioma staging than previously thought. Mesothelioma patients with cancer in these nodes lived half as long as other mesothelioma patients. Researchers in Maryland and Pennsylvania say removing and examining these nodes may lead to more accurate staging, more informed treatment decisions, and better outcomes. How Lymph Nodes … Continue reading Pleural Mesothelioma Staging: These Overlooked Lymph Nodes Might Help
An international team of researchers says it is time to refine the pathological diagnosis of mesothelioma. They are recommending a list of changes they say could make the process more effective. Mesothelioma is a deadly cancer caused by asbestos exposure. Under current pathology guidelines, it falls into just three categories. But the research team says those guidelines do not give doctors enough information. They recommend updates to make the pathological diagnosis of mesothelioma more specific. Understanding Mesothelioma Pathology Pathologists study body tissue, fluids, and cells that are surgically removed. The pathological diagnosis of mesothelioma involves looking at cells under a microscope. Cells can then be put into a category. About three quarters of mesothelioma cases are epithelioid. Epithelioid mesothelioma is … Continue reading The Pathological Diagnosis of Mesothelioma: New Recommendations
Cancer researchers in New York are exploring the concept of using step counts for cancer prognosis. If further studies back it up, the technique might help predict outcomes for people with mesothelioma. The new study involved people with non-small cell lung cancer. The patients wore commercial fitness trackers so doctors could see how much they walked. The researchers compared step levels with treatment outcomes. They concluded that there is value to using step counts for cancer prognosis. It may even be more effective than some more traditional methods for predicting survival. Cancer Prognosis and Chemoradiotherapy Mesothelioma survival usually depends on how well patients respond to standard treatments. Healthier, more active cancer patients tend to have better outcomes. Chemotherapy and radiation … Continue reading Step Counts for Cancer Prognosis: Could it Work for Mesothelioma?
A new study out of Brazil suggests that many older mesothelioma patients may be at risk for malnutrition and the problems that go with it. The study included more than 4,500 Brazliian cancer patients from 45 hospitals. They were evaluated for their nutritional status, nutritional risk, and nutrition-related symptoms. Among the 25% of cancer patients over 65, more than half faced a moderate to severe risk for malnutrition. The findings suggest it is a problem hospitals should identify and address early for the best mesothelioma treatment outcomes. Mesothelioma and Nutritional Status As with other types of cancer, nutrition has an affect on the treatment of people with mesothelioma. An Australian study of pleural mesothelioma patients earlier this year found that … Continue reading Risk for Malnutrition Among Older Mesothelioma Patients
There is more evidence that surgery and intraperitoneal chemotherapy can lead to long-term mesothelioma survival. The news comes from an Australian study of more than 1,200 cancer patients. The study finds that one in five peritoneal mesothelioma patients who had this treatment combination were still alive 10 years later. Peritoneal Cancer Survival with Surgery Peritoneal cancers occur on the lining of the abdomen. Peritoneal mesothelioma starts on this peritoneal membrane. Some other peritoneal cancers start elsewhere in the body and spread to the peritoneum. The new Australian study analyzed the cases of peritoneal cancer patients who had cytoreductive surgery between 1996 and 2018. Cytoreductive surgery aims to remove as much of the cancer as possible. Past studies have found that … Continue reading Large Study Finds Treatment Combination Leads to Long-Term Mesothelioma Survival
New guidelines may make it easier to tell which mesothelioma patients contracted the disease because of a BAP1 gene mutation. The knowledge could have an impact on mesothelioma treatment planning. BAP1 stands for BRCA associated protein-1. People who have an inherited BAP1 gene mutation face a higher risk for several conditions, including malignant mesothelioma. Very few mesothelioma patients have the mutation and gene testing is not routine. So researchers at a top US cancer center have developed a set of screening criteria. The criteria may help predict which mesothelioma patients could benefit from genetic testing. Testing for the Altered Gene Mesothelioma is just one of the conditions associated with the inherited BAP1 gene mutation. People with this condition are also … Continue reading Spotting the BAP1 Gene Mutation in Mesothelioma Patients