Is Asbestos Fiber Type or Concentration More Important in Mesothelioma?

Is Asbestos Fiber Type or Concentration More Important in Mesothelioma?

Malignant pleural mesothelioma is strongly associated with occupational asbestos exposure. The total asbestos fiber concentration may be associated with an increased risk of mortality. Asbestos fiber type was not as important. A new study looked at different types and concentrations of asbestos fibers in the lung tissues of mesothelioma patients. The team investigated their effects on patient mortality. Asbestos Fiber Analyses A Finnish team of scientists identified 590 patients to study. All patients had malignant pleural mesothelioma and underwent pulmonary asbestos fiber analysis. A pulmonary asbestos fiber type analysis is a special clinical test. It extracts fibers and asbestos bodies from a patient’s lung tissue. Usually, this uses a digestion-and-concentration technique. The examination may even include electron diffraction and energy-dispersive … Continue reading Is Asbestos Fiber Type or Concentration More Important in Mesothelioma? »

A New Prognostic Signature Discovered for Malignant Pleural Mesothelioma

New Prognostic Signature Discovered for Malignant Pleural Mesothelioma

Immune-related genes play an important role in malignant pleural mesothelioma prognosis. They can affect the tumor immune microenvironment and affect tumor prognosis. Immune-related genes can be used to predict the course of a disease or patient outcomes. These genes are often called a genetic prognostic signature. Chinese surgeons recently discovered a prognostic signature for malignant pleural mesothelioma patients. Constructing a Prognostic Signature with 5 Immune-Related Genes Genes play an important role in the development and progression of cancers like mesothelioma. The Chinese researchers started by searching for other studies on mesothelioma prognosis and genes. Researchers used data from the Cancer Genome Atlas to construct the prediction signature. Patients were divided into high-risk and low-risk groups. They also used this data … Continue reading A New Prognostic Signature Discovered for Malignant Pleural Mesothelioma »

Gender Differences in Men versus Women with Mesothelioma

Gender Differences in Men versus Women with Mesothelioma

Asbestos is toxic and cancer-causing for human beings. Asbestos causes mesothelioma and other asbestos related diseases. Asbestos-related diseases affect men and women differently. A recent study looked at Brazilian patients with asbestos-related diseases. These included mesothelioma, asbestosis, and lung and ovarian cancer. Introduction Mesothelioma, asbestosis, and pleural plaques are the main asbestos-related diseases. Many consider mesothelioma as the fingerprint of asbestos usage. Between 1961 and 2017, more 7 million tons of asbestos were consumed in Brazil. Mesothelioma from occupational exposure is most common in men. They were often exposed to asbestos at the job site. The number of non-occupational exposures is higher in women. Women are often exposed to asbestos from domestic and environmental sources. It has been difficult to … Continue reading Gender Differences in Men versus Women with Mesothelioma »

Body Swelling and Joint Pain in Malignant Pleural Mesothelioma

Body Swelling and Joint Pain in Malignant Pleural Mesothelioma

The diagnosis of malignant pleural mesothelioma often includes widespread body inflammation. Inflammation and body swelling occur when white blood cells try to protect against infection. Symptoms of inflammation are often redness, swelling, and joint pain or stiffness. Oncologists have studied the relationship between swelling and cancer for 150 years. New research was recently published in the scientific journal Lung Cancer. French medical oncologists believe that patients with more body swelling may have shorter survival. This suggests that body swelling may play a big role in malignant pleural mesothelioma. Body Swelling to Predict a Developing Mesothelioma Diagnosis Prediction of diagnosis is important for malignant pleural mesothelioma patients. The sooner a patient can be diagnosed, the better their outcomes. Oncologists suggest that … Continue reading Body Swelling and Joint Pain in Malignant Pleural Mesothelioma »

Living With Mesothelioma: Coping Strategies to Find Hope

Living With Mesothelioma: Coping Strategies to Find Hope

Mesothelioma is a cancer caused by exposure to asbestos. One key question remains unanswered. How do diagnosed patients experience living with mesothelioma? A new study in Health Psychology aimed to explore the mesothelioma patient experience. Data from 22 different research studies were analyzed. The coping strategies highlighted here provide hope for mesothelioma patients and caregivers. The results bring awareness of the patient experience, coping processes, and support pathways. Two Coping Strategies to Support a Mesothelioma Patient The best coping strategies help patients reclaim a sense of mental calm, individual autonomy, and meaning. These strategies can also reduce the trauma of living with mesothelioma. Patients who accepted the diagnosis fully were more optimistic than those in denial. Patients who accepted the … Continue reading Living With Mesothelioma: Coping Strategies to Find Hope »

New Cancer Guidelines to Manage and Treat Mesothelioma

Updating Mesothelioma Cancer Guidelines from a Global Perspective

Malignant pleural mesothelioma is a type of cancer that develops from the thin layer of tissue that covers many of the body’s internal organs. Mesothelioma is a difficult disease to study on a global scale for many reasons. Yet, there has been tremendous progress in mesothelioma research over the last decade. However, current cancer guidelines are fragmented. An editorial in the Annals of Oncology recommends that new guidelines need to focus on both global and gender perspectives. Shifting Timeframes Make it Difficult to Study Mesothelioma Cases of mesothelioma are rising in some countries and falling in others. This makes it difficult to study the disease on a global level. There are a few different reasons for this global variation. First, … Continue reading New Cancer Guidelines to Manage and Treat Mesothelioma »

Dentists Exposed to Asbestos Could Trigger Malignant Mesothelioma

Dentists Exposed to Asbestos Could Trigger Malignant Mesothelioma

Experts have recommended a new plan to warn dentists exposed to asbestos. Asbestos is a naturally occurring mineral that has been found throughout the world. Asbestos is toxic and cancer-causing for human beings. Dentists used asbestos in the manufacture of dental prostheses from the 1960s to 1970s. Generally, those who develop asbestos-related diseases show no signs of illness for a long time after their exposure. It can take from 10 to 40 years or more for symptoms of an asbestos-related condition to appear. Experts have recommended a new plan to prevent asbestos exposure in dentistry. This recommendation was created under the EuropeAid Assessment Guidelines. Experts also request the inclusion of the dental sector in the lists of professions with asbestos exposure. … Continue reading Dentists Exposed to Asbestos Could Trigger Malignant Mesothelioma »

Lower Platelet Count Linked to Longer Mesothelioma Survival

Lower Platelet Count Linked to Higher Survival Rates

A high platelet count may not bode well for people battling malignant pleural mesothelioma. New evidence suggests that survival rates may be higher for mesothelioma patients with a lower platelet count. This news comes from the Kocaeli University which analyzed malignant mesothelioma patients between 2008 and 2014. They wanted to know if certain clinical characteristics could predict longer patient survival. Platelets and Health Mesothelioma is a rare form of cancer. It develops from cells of the mesothelium, the lining that covers many of the internal organs of the body. While it is uncommon, it has a high mortality rate. Smaller than either red or white blood cells, platelets are the components in blood that facilitate clotting. The normal range for platelet … Continue reading Lower Platelet Count Linked to Longer Mesothelioma Survival »

Asbestos Exposure in Construction Workers Leads to Mesothelioma

Asbestos Exposure in Construction Workers Leads to Mesothelioma

Asbestos exposure in construction workers remains a particular concern. Malignant mesothelioma is a rare cancer with a global incidence. Italy is among the countries with the highest values of mesothelioma. Mesothelioma is associated with exposures to asbestos fibers and other asbestiform fibers. Asbestos exposure in construction workers remains a particular concern. A new study describes the characteristics of Italian malignant mesothelioma cases among construction workers. Scientists analyzed 31,572 cases with definite asbestos exposure in the period from 1993 to 2018. Connecting Asbestos Exposure and Mesothelioma in Construction Workers The relation between asbestos use and the historical trend of mesothelioma is clear. Italian scientists assessed asbestos exposure in 78.2% of the mesothelioma cases. This accounts for 24,864 of the patients studied. … Continue reading Asbestos Exposure in Construction Workers Leads to Mesothelioma »

Nivolumab + Ipilimumab Provides Long-Term Survival Benefit in Malignant Pleural Mesothelioma

Nivolumab + Ipilimumab Provides Long-Term Survival Benefit

Nivolumab + ipilimumab continues to provide a long-term survival benefit in malignant pleural mesothelioma. A new report shows a 3-year follow-up in the CheckMate Clinical Trial. Long-term clinical benefits remained the same for all patient groups. Background on the Nivolumab + Ipilimumab Treatment Two years ago, the FDA approved the combination of nivolumab + ipilimumab. It is the first-line treatment for patients with metastatic non-small cell lung cancer. The CHECKMATE randomized multi-part trial investigated the effectiveness. The trial showed a significant improvement in patient survival. Today, this treatment combination improves patient survival rates over chemotherapy. Mesothelioma patients showed an improved survival using this line of treatment. A new report from the Annals of Oncology describes updated data with at least … Continue reading Nivolumab + Ipilimumab Provides Long-Term Survival Benefit in Malignant Pleural Mesothelioma »

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