The developers of a machine learning tool called MesoNet say the program can predict mesothelioma survival better than a pathologist. MesoNet is a deep convolutional neural network. It analyzes digitized images of mesothelioma cells to predict overall survival. In a new article in Nature Medicine, its creators compared the machine learning tool with pathologist-read slides. Then they validated MesoNet with two different sets of mesothelioma patients. The result may offer a new, more accurate approach to mesothelioma treatment planning. What is a Machine Learning Tool? A machine learning tool is a computer program that gets “smarter” the more it runs. A deep convolutional neural network is a type of machine learning tool that analyzes images. The more images it analyzes, … Continue reading Machine Learning Tool May Predict Mesothelioma Survival Better Than Pathologists
Financial stress during treatment is likely to have an impact on both quality of life and outcomes for pleural mesothelioma patients. That finding comes from a recent Johns Hopkins study of patients with newly-diagnosed lung cancer. The study found that cancer patients who were under financial strain had decreased quality of life. The report appears in the International Journal of Radiation Oncology. It includes a list of guidelines to help identify patients at risk for “financial toxicity”. The Financial Burden of Mesothelioma Treatment Cancer treatment is rarely inexpensive. Thanks to advances in mesothelioma therapies, patient outcomes are improving. But the costs of these cutting-edge mesothelioma treatments can be even higher than standard therapies. John Hopkins researchers wanted to see if … Continue reading Financial Stress Could Impact Mesothelioma Quality of Life
An international team of researchers says it is time to refine the pathological diagnosis of mesothelioma. They are recommending a list of changes they say could make the process more effective. Mesothelioma is a deadly cancer caused by asbestos exposure. Under current pathology guidelines, it falls into just three categories. But the research team says those guidelines do not give doctors enough information. They recommend updates to make the pathological diagnosis of mesothelioma more specific. Understanding Mesothelioma Pathology Pathologists study body tissue, fluids, and cells that are surgically removed. The pathological diagnosis of mesothelioma involves looking at cells under a microscope. Cells can then be put into a category. About three quarters of mesothelioma cases are epithelioid. Epithelioid mesothelioma is … Continue reading The Pathological Diagnosis of Mesothelioma: New Recommendations
New research suggests that it may be possible to predict which mesothelioma patients are at risk for opioid addiction. The research comes from the University of California. Scientists analyzed more than a hundred thousand cancer cases to come up with a list of risk factors for opioid addiction. The information could help doctors select other, less dangerous ways of managing pain in high risk mesothelioma patients. Mesothelioma Pain and Opioid Addiction Chest pain is a symptom of pleural mesothelioma. People with peritoneal mesothelioma may experience abdominal pain. As the disease progresses or lung fluid builds up, that pain can impact quality of life. Many mesothelioma patients also experience pain after surgery. Managing pain is a significant part of care for … Continue reading Predicting Opioid Addiction in Mesothelioma Patients
New research in Southern Italy highlights the global problem of mesothelioma among construction workers. The research comes from occupational medicine experts at the University of Bari. Scientists studied 178 cases of mesothelioma among construction workers in the Apulia region of Italy. The data shows that heavy asbestos exposure raised the odds of contracting mesothelioma by more than two-and-a-half times. Asbestos and the Risk for Mesothelioma Asbestos is the primary cause of mesothelioma, in Italy and around the world. But for decades, almost no one knew that. Tens of thousands of people worked with asbestos before scientists recognized the risk for mesothelioma among construction workers. Asbestos was in dozens of construction products including cement, wall board, insulation, floor and ceiling tiles … Continue reading Mesothelioma Among Construction Workers in Southern Italy
There has been a setback for researchers focused on the promise of pembrolizumab for mesothelioma. New research suggests that pembrolizumab (Keytruda) may not be the miracle mesothelioma drug that some were hoping for. The Phase III trial results were presented at a the European Society of Medical Oncology conference now underway in Spain. They suggest that pembrolizumab for mesothelioma may be no better than chemotherapy for improving survival. Pembrolizumab for Mesothelioma: How it Works Malignant pleural mesothelioma is a rare but lethal cancer. It is usually associated with on-the-job asbestos exposure. There is no cure. The only drug approved for mesothelioma treatment is Alimta (pemetrexed). Cancer researchers around the world are working hard to find other mesothelioma treatments. Pembrolizumab for … Continue reading Pembrolizumab for Mesothelioma Dealt Setback by New Trial Results
Cancer researchers in New York are exploring the concept of using step counts for cancer prognosis. If further studies back it up, the technique might help predict outcomes for people with mesothelioma. The new study involved people with non-small cell lung cancer. The patients wore commercial fitness trackers so doctors could see how much they walked. The researchers compared step levels with treatment outcomes. They concluded that there is value to using step counts for cancer prognosis. It may even be more effective than some more traditional methods for predicting survival. Cancer Prognosis and Chemoradiotherapy Mesothelioma survival usually depends on how well patients respond to standard treatments. Healthier, more active cancer patients tend to have better outcomes. Chemotherapy and radiation … Continue reading Step Counts for Cancer Prognosis: Could it Work for Mesothelioma?
There is new evidence supporting the use of low-dose aspirin for cancer survival. The evidence comes from two new retrospective studies. The first involved patients with head and neck cancer. The second focused on patients with early-stage non-small cell lung cancer (NSCLC). NSCLC is similar to mesothelioma in many ways. Mesothelioma is an aggressive cancer that is often fatal within a year of diagnosis. Based on the new findings, some mesothelioma patients may consider talking to their doctors about aspirin for cancer survival Anti-Inflammatories and Cancer Treatment Anti-inflammatory drugs like aspirin can cut the risk for heart disease and heart attack. But research led by the Roswell Park Cancer Center shows they may have similar benefits for people with cancers … Continue reading Should Mesothelioma Patients Take Aspirin for Cancer Survival?
A UK study suggests that successful talc pleurodesis for mesothelioma improves survival better than other lung fluid treatments. Researchers in Oxford’s Chest Diseases Department analyzed the outcomes of two groups of pleural mesothelioma patients. Both groups underwent talc pleurodesis for mesothelioma. The patients whose lung fluid did not come back after treatment experienced longer survival. Mesothelioma patients who had to be retreated did not live as long. Pleural Effusion in Mesothelioma The pleura is a membrane that surrounds and encases the lungs. It is supposed to be flexible and allow the lungs to move when a person breathes. But patients with pleural mesothelioma often develop pleural effusion. Pleural effusion is a build-up of excess fluid in the space between the … Continue reading Talc Pleurodesis for Mesothelioma May Extend Survival
A new article suggests that non-invasive TTFields treatment for mesothelioma has the potential to save lives – as long as enough physicians accept it. TTFields stands for Tumor Treating Fields. It is an electricity-based treatment approved by the FDA for use along with standard mesothelioma chemotherapy. Cancer researchers from West Cancer Center and Research Institute wrote the new article for The Oncologist. They say the success of TTFields treatment for mesothelioma depends on doctors learning the logistics of using it. How Does TTFields Treatment for Mesothelioma Work? TTFields use low-intensity alternating electric fields. When these electric fields hit a mesothelioma tumor, they disrupt normal cell division. If cancer cells cannot divide properly, they are less likely to spread out of … Continue reading TTFields Treatment for Mesothelioma: Physician Acceptance is Critical