News on Mesothelioma | Surviving Mesothelioma

Compound in Broccoli May Enhance Mesothelioma Treatment with Cisplatin

There is new evidence that a compound found in cruciferous vegetables like broccoli and cabbage may enhance the anticancer benefits of the platinum-based drug cisplatin in the treatment of pleural mesothelioma. Although malignant mesothelioma is highly resistant to conventional cancer treatments, most mesothelioma patients will receive chemotherapy with cisplatin and pemetrexed (Alimta) as part of a multi-modal approach to treatment. Now, researchers Yoon-Jin and Sang-Han … Continue reading Compound in Broccoli May Enhance Mesothelioma Treatment with Cisplatin »

MicroRNAs May Be Key to Better Immunotherapy for Mesothelioma

Australian scientists say it may be possible to artificially reduce the levels of a protein that helps mesothelioma tumors hide from the immune system. The new research published in the Journal of Thoracic Oncology could open the door to more effective immunotherapy treatments for pleural mesothelioma. The Importance of PD-L1 Expression A cell surface protein called PD-L1 is key to the effectiveness of several new … Continue reading MicroRNAs May Be Key to Better Immunotherapy for Mesothelioma »

Mesothelioma Risk Continues to Rise for Decades After Asbestos Exposure

Pleural Mesothelioma Incidence

A pair of Polish researchers have confirmed what a number of other studies have suggested – that the risk of contracting malignant mesothelioma continues to rise, even decades after a person’s last exposure to asbestos. The study was conducted by asbestos-exposure experts at the Nofer Institute of Occupational Medicine and included a total of 131 patients with pleural mesothelioma. Another 655 people enrolled in a … Continue reading Mesothelioma Risk Continues to Rise for Decades After Asbestos Exposure »

The Influence of BAP1 on Mesothelioma Survival

A mutation on the BAP1 tumor suppressor gene can influence the development of malignant mesothelioma but may have little bearing on survival. That conclusion comes from a new Chinese study of more than 2,400 people with cancers directly linked to the BAP1 genetic mutation, including pleural mesothelioma. BAP1 and Mesothelioma BRCA1-associated protein 1 (BAP1) is a tumor suppressing protein encoded by the BAP1 gene. Multiple studies … Continue reading The Influence of BAP1 on Mesothelioma Survival »

Boosting Mesothelioma Survival with VEGF-Inhibitor

The VEGF inhibitor cediranib may not yet be out of the running as a mesothelioma treatment. Although previous studies have found it to have dose-limiting side effects, a new study in the Journal of Thoracic Oncology finds that, at the right dose, it could boost the effectiveness of standard mesothelioma chemotherapy. What is Cediranib? Cediranib, an oral drug made by Astra Zeneca, is a powerful … Continue reading Boosting Mesothelioma Survival with VEGF-Inhibitor »

Length of Time Between Surgeries a Marker for Mesothelioma Survival

Peritoneal mesothelioma patients who survive more than two years after surgery are the ones most likely to benefit from a second surgery if their cancer recurs. That is the conclusion of cancer researchers at the City of Hope Cancer Center and Wake Forest School of Medicine in an article newly published in the Journal of Surgical Oncology. Using a City of Hope database of 1,314 … Continue reading Length of Time Between Surgeries a Marker for Mesothelioma Survival »

Asbestos Sprayers Face Higher Lifetime Mesothelioma Risk

Workers whose job it was to apply spray-on asbestos insulation may be at even higher risk for lung cancer and malignant mesothelioma than other types of asbestos workers. A Finnish study of four different groups of asbestos workers found that asbestos sprayers had a standardized incidence ratio (SIR) for malignant mesothelioma as much as 100 times that of the general population. The Danger of Spray-On … Continue reading Asbestos Sprayers Face Higher Lifetime Mesothelioma Risk »

A Breath Test for Mesothelioma?

Researchers in Belgium say a breath analysis tool could provide the next big breakthrough in the effort to diagnose malignant mesothelioma earlier. The team, made up of scientists from Ghent and Antwerp Universities, says the technique looks “very promising” and fits well within the aims of the “National Cancer Moonshot” research initiative established by President Obama. The Challenge of Mesothelioma Diagnosis Malignant pleural mesothelioma (MPM) … Continue reading A Breath Test for Mesothelioma? »

New Blood Test Could Mean Earlier Mesothelioma Diagnosis

A calcium-binding protein called calretinin may provide the basis for a new kind of blood test for the asbestos-linked cancer, malignant mesothelioma. Right now, there is no reliable way to detect the presence of a mesothelioma tumor before symptoms develop. The Search for a Mesothelioma Blood Test But scientists around the world are searching for ways to use certain compounds produced by tumors to diagnose mesothelioma … Continue reading New Blood Test Could Mean Earlier Mesothelioma Diagnosis »

Cholesterol Drug May Protect Mesothelioma Patients from Radiation

A new study suggests that the cholesterol-lowering drug pravastatin could one-day be used to help protect mesothelioma patients from the damaging side effects of radiotherapy. According to Japanese researchers, mice with malignant mesothelioma who were given pravastatin (Pravachol) in drinking water prior to receiving radiation experienced less damage to healthy cells in their lungs and intestines. The results suggest that pravastatin might make radiotherapy safer … Continue reading Cholesterol Drug May Protect Mesothelioma Patients from Radiation »

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