Vaccine Archives | Surviving Mesothelioma

Mayo Researchers Fight Mesothelioma with Measles Virus

The same virus that can make unvaccinated children come down with spots and fevers may provide the basis for a powerful new weapon against the intractable cancer, malignant pleural mesothelioma. New research being conducted at the University of Minnesota and the Mayo Clinic suggests that a strain of the measles virus called MV-Edm (the Edmonston strain) has the unique ability to not only target and … Continue reading Mayo Researchers Fight Mesothelioma with Measles Virus »

Fast-Tracked Mesothelioma Drug Set for Phase 3 Trials

woman mesothelioma doctor holds syringe

By this time next year, a pivotal Phase 3 trial will be underway on what looks to be one of the most promising new therapies for malignant pleural mesothelioma.   The makers of galinpepimut-S, an immunotherapy vaccine with Orphan Drug status for acute myeloid leukemia and pleural mesothelioma, recently announced their intention to begin the Phase 3 mesothelioma trial in mid-2017. The news was punctuated by … Continue reading Fast-Tracked Mesothelioma Drug Set for Phase 3 Trials »

Enzyme Blockers May Offer Innovative New Mesothelioma Treatment

physician

Cancer drugs that block an enzyme called EZH2 could be a “tremendous innovation” for mesothelioma patients, according to researchers at Memorial Sloan Kettering Cancer Center in New York. Recent research on mice at Memorial Sloan Kettering found that elevated levels of EZH2 allowed mesothelioma to grow out of control and that blocking the enzyme inhibited the growth of mesothelioma tumors. A New Kind of Mesothelioma … Continue reading Enzyme Blockers May Offer Innovative New Mesothelioma Treatment »

New Immunotherapy for Mesothelioma Relies on Altered T-Cells

An emerging type of mesothelioma therapy that uses altered T-cells to attack tumors is generating some excitement among researchers at Memorial Sloan Kettering Cancer Center in New York. The approach, called CAR T-cell therapy, produces what the National Cancer Institute has called a “living drug” for targeted mesothelioma treatment. A new review of this immunotherapy approach has some encouraging news for mesothelioma patients and their … Continue reading New Immunotherapy for Mesothelioma Relies on Altered T-Cells »

Immunotherapy Drug: More May be Better for Advanced Mesothelioma

The same team of Italian researchers that first reported on the safety and efficacy of the immunotherapy drug tremelimumab for mesothelioma now say that giving more of the drug might be even more effective. Tremelimumab is a monoclonal antibody that acts on a particular downregulator of the immune system called cytotoxic T-lymphocyte antigen 4 (CTLA4). The goal of tremelimumab is to inhibit the immune system … Continue reading Immunotherapy Drug: More May be Better for Advanced Mesothelioma »

Mesothelioma Vaccine Receives Orphan Drug Approval

woman mesothelioma doctor holds syringe

Mesothelioma patients who are not candidates for surgery may soon have another treatment option. The FDA has granted orphan drug approval to a new cancer vaccine called CRS-207. CRS-207 is manufactured by Aduro Biotech, Inc. and is made from an attenuated (less potent) version of the bacteria Listeria monocytogenes. CRS-207 triggers a powerful immune response against cells that produce mesothelin, a tumor-associated antigen produced by … Continue reading Mesothelioma Vaccine Receives Orphan Drug Approval »

Australian Doctors Use Bacteria to Shrink Mesothelioma Tumors

Could bacteria responsible for problems ranging from sinusitis to food poisoning be used as a weapon in the fight against malignant mesothelioma? The results of a new study conducted by mesothelioma researchers at the University of Western Australia suggest that it might. The researchers focused their study on a compound made up of proteins produced by the bacteria Staphylococcus aureus, also called ‘Staph’ bacteria. The … Continue reading Australian Doctors Use Bacteria to Shrink Mesothelioma Tumors »

Mesothelioma Vaccine Enters Phase 2 Testing

The makers of a new cancer vaccine say they have enrolled the first mesothelioma patients in a study that will combine their drug with chemotherapy against this virulent cancer. The drug, currently known as CRS-207, is manufactured by Aduro Bio Tech, Inc. According to a company press release, CRS-207 is based on an attenuated (made less potent) version of Listeria monocytogenes, bacteria found in soil and water … Continue reading Mesothelioma Vaccine Enters Phase 2 Testing »

Mesothelioma Vaccine Jump Starts Immunity

Scientists studying a vaccine for mesotheliomahave published some of their most important preliminary data in the respected medical journal Lung Cancer.  Mesothelioma, a cancer of the organ linings caused by asbestos exposure, is highly resistant to conventional treatments.  Not only does it grow quickly, but its shape makes detection and removal difficult. Unlike some other types of solid tumors which may grow in a mass, mesothelioma tumors … Continue reading Mesothelioma Vaccine Jump Starts Immunity »

White Blood Cells May Predict Mesothelioma Survival

Certain types of white blood cells may hold important survival clues – as well as a new treatment target – for mesothelioma patients and their doctors. Malignant pleural mesothelioma can result when inhaled asbestos fibers trigger physiological changes in the lung tissue. Medical science has yet to find a reliable way to stop the spread of mesothelioma once it begins and many patients succumb to … Continue reading White Blood Cells May Predict Mesothelioma Survival »

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