Biological Therapy | Surviving Mesothelioma

Searching for New Mesothelioma Drugs Among African Plants

Doctors in Cameroon and Turkey say two types of African plants deserve more study as potential treatments for malignant mesothelioma and other intractable cancers. The plants, including Elephantopus mollis,, Kalanchoe crenata, and four other medicinal plants, contain compounds that triggered cell death when tested on mesothelioma cells in the laboratory. At present, there is no cure for mesothelioma and no drugs that consistently slow its … Continue reading Searching for New Mesothelioma Drugs Among African Plants »

The Key to Mesothelioma Treatment Success with Immunotherapy

Researchers with a biotechnology company that makes antibody-drug conjugates (ADC) for hard-to-treat cancers like malignant mesothelioma say careful patient selection is the key to treatment success. Writing in the journal Advances in Therapy, John Lambert and Charles Morris of Massachusetts-based ImmunoGen call for the development of a “patient selection strategy” so that more mesothelioma patients and those with other cancers can take advantage of the … Continue reading The Key to Mesothelioma Treatment Success with Immunotherapy »

Compound in Pacific Sea Squirt Kills Mesothelioma Cells

There is new evidence that compounds isolated from a sea squirt found in the waters off of the Indonesian coast may hold the key to fighting mesothelioma and several other malignancies. The potential anticancer and antimicrobial properties are found in polysulfur aromatic alkaloids found in a Pacific sea squirt whose scientific name is Lissoclinum badium. In a new article in the Journal of Natural Products, … Continue reading Compound in Pacific Sea Squirt Kills Mesothelioma Cells »

Attacking Pleural Mesothelioma From the Inside Out

There is new evidence that manipulating the process of protein synthesis inside cancer cells could be the key to improving mesothelioma  outcomes for certain patients. A new study published in the Journal of the American Medical Association (JAMA) Oncology suggests that using a drug to lower the levels of the amino acid arginine can slow the spread of pleural mesothelioma and extend survival in patients … Continue reading Attacking Pleural Mesothelioma From the Inside Out »

New Drug Combination May Extend Mesothelioma Survival

A drug derived from the eggs of leopard frogs may offer new hope for people with intractable malignant mesothelioma – especially if the drug is administered in combination with a malaria drug called dihydroartemisinin (DHA). A newly-published Chinese report suggests that the combination has anti-tumor effects on non-small cell lung cancer and malignant mesothelioma not seen with conventional cancer drugs. A Winning Drug Combination? Onconase … Continue reading New Drug Combination May Extend Mesothelioma Survival »

Investigational Mesothelioma Drug to be Tested in Human Patients

Researchers in Japan say they are about to start the first clinical trial of an investigational mesothelioma drug that has shown promise in animals. The drug is a monoclonal antibody called YS110 that targets a protein called CD26. CD26 is believed to play a role in mesothelioma tumor growth and invasion and in the process of cell death known as apoptosis. It is overexpressed in … Continue reading Investigational Mesothelioma Drug to be Tested in Human Patients »

New Immunotherapy Drug Works Synergistically to Fight Malignant Mesothelioma

The creators of a new kind of cancer drug based on an altered cold virus say it appears to work synergistically with standard chemotherapy to combat malignant pleural mesothelioma. Malignant mesothelioma affects an estimated 2,500 people in the US each year and tens of thousands more around the world. It is caused almost exclusively by exposure to asbestos. Although chemotherapy with pemetrexed (Alimta) and a platinum drug … Continue reading New Immunotherapy Drug Works Synergistically to Fight Malignant Mesothelioma »

New Insights Into Immunotherapy for Mesothelioma

The development of excess fluid in the space around the lungs is a common side effect of malignant pleural mesothelioma. This fluid, known as malignant pleural effusion, contains mesothelioma cells. Because it is relatively easy to obtain a sample of this fluid with a needle (as opposed to performing a tissue biopsy), it is often used to reveal important information about a patient’s mesothelioma tumor. … Continue reading New Insights Into Immunotherapy for Mesothelioma »

Investigational Drugs May Offer New Ways to Treat Malignant Mesothelioma

There is some exciting news for patients fighting malignant mesothelioma this week. Two new potential mesothelioma drugs, both aimed at molecular targets, have moved a step closer to becoming viable treatment options.   Mesothelioma Growth Inhibitor The first drug making news this week is YS110, a monoclonal antibody that targets a protein called CD26. CD26 is believed to play a role in mesothelioma tumor growth … Continue reading Investigational Drugs May Offer New Ways to Treat Malignant Mesothelioma »

Phenomenal Response to New Mesothelioma Immunotherapy Drug

There is some exciting news from the front lines of mesothelioma research this week. California scientists say they have dramatically improved the effectiveness of mesothelioma chemotherapy by pairing it with a an immunotherapy drug made of live bacteria. The University of California, San Francisco team presented their findings to other lung cancer experts at the international European Lung Cancer Conference in Switzerland earlier this week. … Continue reading Phenomenal Response to New Mesothelioma Immunotherapy Drug »

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