Asia Archives | Surviving Mesothelioma

Mesothelioma Biomarker Test May Be Diagnostic Alternative for Frail Patients

A set of proteins found in the lung fluid of people with malignant pleural mesothelioma may offer a safer way to diagnose the asbestos cancer in frail or elderly patients. Mesothelioma is an extremely difficult cancer to diagnose. Accurate diagnosis usually requires a combination of tests including a physical exam, a thorough work history (including possible asbestos exposure), blood or lung fluid tests, imaging scans, … Continue reading Mesothelioma Biomarker Test May Be Diagnostic Alternative for Frail Patients »

Radical Surgery Alone Unlikely to Prolong Mesothelioma Survival

Extrapleural pneumonectomy, the most radical – and risky – type of surgery for malignant pleural mesothelioma, is more likely to lead to long term survival when paired with strategic follow-up treatments. That is the conclusion of researchers at Japan’s Kyushu University who conducted a retrospective study of 10 mesothelioma patients who underwent EPP at their institution between 2001 to 2010. EPP Surgery and Mesothelioma Outcomes … Continue reading Radical Surgery Alone Unlikely to Prolong Mesothelioma Survival »

Inflammation Marker May Predict Mesothelioma Prognosis

The ratio of neutrophils to lymphocytes – a way of measuring inflammation in the body of people with malignant pleural mesothelioma – may help doctors predict how well they will respond to treatment. That is the conclusion of mesothelioma researchers at China’s Sichuan University. In a new article in the journal Oncotarget, the team observed that NLR has been associated with survival in other types … Continue reading Inflammation Marker May Predict Mesothelioma Prognosis »

The World’s Workers Still Dying From Malignant Mesothelioma

An international study of malignant mesothelioma suggests that deaths from the asbestos cancer have increased in recent years, in spite of advances in diagnostic and treatment tools. The study included data and estimates on deaths from malignant mesothelioma in 230 countries between 1994 and 2014. Based on information obtained from the World Health Organization, a team of scientists in Japan, Australia, Singapore, Thailand, the US, … Continue reading The World’s Workers Still Dying From Malignant Mesothelioma »

These Proteins Appear to Shorten Mesothelioma Survival

New evidence suggests that mesothelioma patients whose tumors express two particular proteins do not live as long as other mesothelioma patients. An international team of scientists including mesothelioma researchers at the National Cancer Institute say ALCAM (also called CD166) and PD-L1 (CD274) are both associated with “significantly decreased” survival in pleural mesothelioma. Understanding ALCAM and PD-L1 ALCAM is a type I transmembrane protein that regulates … Continue reading These Proteins Appear to Shorten Mesothelioma Survival »

Thoracoscopy Deemed “Valuable and Safe” for Mesothelioma Patients

Pleural mesothelioma patients who are recommended for medical thoracoscopy can rest assured that the procedure is “a valuable and safe” diagnostic tool. That is the message from Chinese researchers after an analysis of nine years of medical thoracoscopies on more than 800 patients with malignant mesothelioma and other pleural cancers at a Beijing hospital. What is Medical Thoracoscopy? Medical thoracoscopy is a minimally invasive procedure … Continue reading Thoracoscopy Deemed “Valuable and Safe” for Mesothelioma Patients »

Compound in Broccoli May Enhance Mesothelioma Treatment with Cisplatin

There is new evidence that a compound found in cruciferous vegetables like broccoli and cabbage may enhance the anticancer benefits of the platinum-based drug cisplatin in the treatment of pleural mesothelioma. Although malignant mesothelioma is highly resistant to conventional cancer treatments, most mesothelioma patients will receive chemotherapy with cisplatin and pemetrexed (Alimta) as part of a multi-modal approach to treatment. Now, researchers Yoon-Jin and Sang-Han … Continue reading Compound in Broccoli May Enhance Mesothelioma Treatment with Cisplatin »

The Influence of BAP1 on Mesothelioma Survival

A mutation on the BAP1 tumor suppressor gene can influence the development of malignant mesothelioma but may have little bearing on survival. That conclusion comes from a new Chinese study of more than 2,400 people with cancers directly linked to the BAP1 genetic mutation, including pleural mesothelioma. BAP1 and Mesothelioma BRCA1-associated protein 1 (BAP1) is a tumor suppressing protein encoded by the BAP1 gene. Multiple studies … Continue reading The Influence of BAP1 on Mesothelioma Survival »

Cholesterol Drug May Protect Mesothelioma Patients from Radiation

A new study suggests that the cholesterol-lowering drug pravastatin could one-day be used to help protect mesothelioma patients from the damaging side effects of radiotherapy. According to Japanese researchers, mice with malignant mesothelioma who were given pravastatin (Pravachol) in drinking water prior to receiving radiation experienced less damage to healthy cells in their lungs and intestines. The results suggest that pravastatin might make radiotherapy safer … Continue reading Cholesterol Drug May Protect Mesothelioma Patients from Radiation »

Predicting Mesothelioma Outcomes with Soluble Mesothelin

New research suggests that a protein often used to help diagnose and track malignant mesothelioma may also be a valuable prognostic indicator. Soluble mesothelin-related protein (SMRP) is a biomarker for pleural mesothelioma, an aggressive asbestos-linked cancer that causes few symptoms until in its late stages. The presence of SMRP in the blood indicates that mesothelial cells on the lining around the lungs have been damaged. … Continue reading Predicting Mesothelioma Outcomes with Soluble Mesothelin »

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