Pleural Mesothelioma Patients are Stronger a Year After Surgery

pleural mesothelioma patients

Pleural mesothelioma patients can be stronger and have better lung function a year after surgery than in the days and weeks immediately following their operation. That’s the finding of Japanese researchers who just published a new study in Integrative Cancer Therapies.  They tested 24 male pleural mesothelioma patients in their 60s and 70s. They measured things like the mens’ grip strength, knee extension strength, and how far they could walk in six minutes. They also ran several tests on their lung function. They compared these test results with the patients’ own assessment of their outcomes.  The study suggests that patients who undergo P/D surgery can continue to improve beyond the postoperative phase. It is a hopeful message for patients and … Continue reading Pleural Mesothelioma Patients are Stronger a Year After Surgery »

Neoadjuvant Chemotherapy Plus Surgery for Pleural Mesothelioma: A Prospective Study

neoadjuvant chemotherapy

A new prospective Japanese mesothelioma study shows the potentially life-saving benefits of undergoing neoadjuvant chemotherapy followed by surgery. This has been the preferred way to treat pleural mesothelioma for many years. But most of the studies on it are retrospective. This means that researchers analyze data on mesothelioma patients who already had treatment. In many cases, they are patients who have died.  The new study is one of the few prospective studies on neoadjuvant chemotherapy and mesothelioma surgery.  In a prospective study, researchers enroll patients and follow their progress through treatment.  Pleural mesothelioma is often fatal within a few months. But ninety-five percent of the study subjects who had presurgical chemotherapy followed by an operation were still alive a year … Continue reading Neoadjuvant Chemotherapy Plus Surgery for Pleural Mesothelioma: A Prospective Study »

Asbestos Bans Not a Quick Fix for Rising Mesothelioma Incidence

mesothelioma incidence

A new study is further evidence that asbestos bans are not a quick fix for the global problem of malignant mesothelioma incidence.  Researchers in China and the US just released a worldwide research study on the asbestos cancer. The study included 21 regions in 195 countries and territories and spanned 27 years.  The authors say mesothelioma incidence does decrease after asbestos bans. But the decrease can take decades. In the meantime, they say many countries need to do a better job of tracking and managing mesothelioma cases.  Asbestos and Mesothelioma Incidence Malignant mesothelioma is an aggressive cancer with a poor prognosis. Exposure to asbestos is its only known cause. People with mesothelioma often die of this cancer in less than … Continue reading Asbestos Bans Not a Quick Fix for Rising Mesothelioma Incidence »

South Korean Mesothelioma Rates Still Rising Decades After Asbestos Ban

asbestos ban

A new report out of South Korea is proof that it can take many years for mesothelioma rates to decline even after implementing an asbestos ban. Asbestos is the number one cause of malignant mesothelioma worldwide. South Korea banned asbestos in 2009. But a report in the International Journal of Environmental Research and Public Health shows the country will likely be dealing with the after-effects well into the future.  A national asbestos ban is a vital step toward fighting occupational cancer. But the new study is a sobering reminder that it cannot eliminate mesothelioma overnight.  Occupational Risk for Malignant Mesothelioma Mesothelioma can be a health hazard for anyone who ever worked with or around asbestos.  Once a worker inhales or … Continue reading South Korean Mesothelioma Rates Still Rising Decades After Asbestos Ban »

Japanese Researchers Discover ‘Novel Diagnostic Marker’ for Mesothelioma

novel diagnostic marker

A protein called CDLN15 could be a novel diagnostic marker for malignant pleural mesothelioma, allowing doctors to pinpoint asbestos cancer earlier and boost the odds of survival. That is the message from a recently published Japanese study.  Pleural mesothelioma is notoriously difficult to diagnose. It rarely causes any symptoms at all until it is in a late stage. When the symptoms do show up, they are easy to confuse with other illnesses. Earlier diagnosis of pleural mesothelioma depends on finding things that set it apart from other diseases. This novel diagnostic marker could serve as a red flag for this rare but deadly cancer.  CDLN15 as a Novel Diagnostic Marker CDLN15 stands for claudin-15. Claudins are a family of proteins … Continue reading Japanese Researchers Discover ‘Novel Diagnostic Marker’ for Mesothelioma »

Artificial Intelligence Improves Mesothelioma Diagnosis, Study Finds

artificial intelligence

There is more evidence that artificial intelligence may have a role to play in helping doctors diagnose deadly malignant mesothelioma earlier.  A study conducted at Japan’s Hyogo College of Medicine used past patient records to test a deep convolutional neural network (CDNN). This is a complex computer program designed to evaluate diagnostic criteria.  Pleural mesothelioma is a difficult cancer for doctors to diagnose. Artificial intelligence can help by quickly comparing diagnostic data to hundreds of past cases. In the Japanese study, the AI produced the most accurate mesothelioma diagnoses when combined with all of the available patient data. The Challenge of Diagnosing Mesothelioma Mesothelioma tumors grow on the membranes around internal organs. They usually come from past exposure to asbestos. … Continue reading Artificial Intelligence Improves Mesothelioma Diagnosis, Study Finds »

Non-Incisional Pleurectomy/Decortication for Mesothelioma

non-incisional pleurectomy/decortication

Non-incisional pleurectomy/decortication could be the wave of the future for malignant mesothelioma treatment.  Environmental health experts in Japan say it is possible to remove the diseased pleural lining in a person with mesothelioma without making incisions that could spread their cancer.  The procedure is called non-incisional pleurectomy/decortication. It is a new way to perform mesothelioma surgery that may be safer, faster, and more effective.  Japanese researchers recently published a report on their experience with the technique. The report appears in the newest issue of General Thoracic and Cardiovascular Surgery. Surgical Treatment of Pleural Mesothelioma Pleural mesothelioma is the most common form of asbestos cancer. It occurs on the pleura, a thin membrane surrounding the lungs. From there, pleural mesothelioma can … Continue reading Non-Incisional Pleurectomy/Decortication for Mesothelioma »

P/D Surgery for Mesothelioma Improves Quality of Life Regardless of Lung Function

P/D Surgery for Mesothelioma

Japanese researchers say P/D surgery for mesothelioma improves quality of life for most patients, even if their lung function gets worse.  Doctors at the Hyogo College of Medicine tracked the cases of forty-five patients who had P/D surgery for mesothelioma between 2014 and 2018.  Lung function tests showed most pleural mesothelioma patients could not breathe as well after surgery as they did before. Their energy, vitality, and social functioning also decreased. But patients reported better mental health after surgery and significantly less pain.  The researchers conclude that quality of life after P/D surgery for mesothelioma may have less to do with breathing than previously thought.  What is P/D Surgery for Mesothelioma? Pleural mesothelioma tumors grow on the pleura, a thin … Continue reading P/D Surgery for Mesothelioma Improves Quality of Life Regardless of Lung Function »

Mesothelioma Surgeries Carry Similar Mortality Risk, Study Finds

mesothelioma surgeries

The two major types of mesothelioma surgeries carry similar risk of death, according to a new study from cancer researchers in Japan.  One surgery involves removing the diseased pleural lining and one of the lungs. The other surgery removes many of the same tissues but leaves the lungs intact.  Surgeons around the world are divided as to which of these mesothelioma surgeries is best. Mesothelioma patients have more complications with lung-removing surgery. But some studies suggest it could lead to longer survival.  The 4-year Japanese study included more than 600 patients. It suggests that the likelihood of dying is similar with either of these mesothelioma surgeries.  Surgical Treatment of Pleural Mesothelioma Pleural mesothelioma is the most common type of asbestos … Continue reading Mesothelioma Surgeries Carry Similar Mortality Risk, Study Finds »

Which Mesothelioma Patients will Benefit from Second-Line Chemotherapy

second-line chemotherapy

Japanese oncologists say they have found a way to help predict which peritoneal mesothelioma patients are most likely to get results from second-line chemotherapy. First-line therapy is the mesothelioma treatment that doctors try first. Usually, that is chemotherapy. If that does not work or stops working, they may move on to another option. Second-line chemotherapy is one of those options.  Doctors at National Cancer Center Hospital in Tokyo evaluated mesothelioma cases. These were patients at their institution between 2007 and 2019. They found that patients who have more rounds of first-line chemotherapy are most likely to respond to second-line chemotherapy.  Drug Treatment for Malignant Mesothelioma Peritoneal mesothelioma is a cancer on the lining that surrounds the abdominal organs. It usually … Continue reading Which Mesothelioma Patients will Benefit from Second-Line Chemotherapy »

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