A procedure normally used to help alleviate pain has been used to successfully stop a case of recurrent malignant pleural mesothelioma in Japan. Radiofrequency ablation (RFA) uses electrical energy delivered through a thin, hollow needle to heat and destroy cancer cells. Most of the time, this technology is used to destroy small tumors or a treat small area of cancer to alleviate symptoms such as pain or discomfort. But thoracic surgeons at the Hyogo College of Medicine in Hyogo, Japan say their new case study suggests that the procedure should also be considered as a definitive treatment — especially for mesothelioma patients for whom surgery is not a viable option. Complex Mesothelioma Case Drives RFA Decision In a new report … Continue reading Radiofrequency Ablation for Recurrent Mesothelioma: A New Treatment Option?
Mesothelioma patients now have a high-tech new way to connect with cutting edge mesothelioma treatments around the world – for a price. A pair of Harvard-trained oncologists have just rolled out a new app that promises to connect people who have cancers like pleural mesothelioma with treatments and clinical trials that even their physicians may not be aware of. The app, called Driver, is being rolled out this week in the US and China in the wake of a trial run with a hundred people over the past year. How Might Driver Help Mesothelioma Patients? One of the biggest obstacles faced by patients diagnosed with rare cancers like pleural or peritoneal mesothelioma is getting the most up-tp-date information about potential … Continue reading Mobile App Could Help Mesothelioma Patients Find New Treatments
South Korean researchers have uncovered a clue that might help explain why mesothelioma tumors are so aggressive — and what can be done to counter that aggression. The new study centers on hypoxia, a deficiency in the amount of oxygen reaching the tissues. It is a hallmark of many types of solid tumors and it turns out that malignant mesothelioma tumors are no exception. Patients with these hypoxic tumors tend to worsen quickly, be less responsive to treatment, and end up with poor outcomes. The Effect of Oxygen on Malignant Mesothelioma Scientists in the Laboratory of Clinical Pathology, College of Veterinary Medicine, Seoul National University are trying to better understand how hypoxia effects human malignant mesothelioma cells and exactly what … Continue reading Mesothelioma Tumors Thrive in Low Oxygen Environment
Japanese pathologists have a new theory that may lead to earlier detection and better outcomes for people with malignant pleural mesothelioma. Researchers led by the International University of Health and Welfare in Tokyo say exposure to asbestos appears to shorten the telomeres that protect the ends of DNA strands. The discovery could give doctors another way to diagnose malignant mesothelioma in time to implement more effective treatments. What are Telomeres? Telomeres are the caps on the end of each strand of DNA. According to Telomere Activation Sciences, telomeres function like the plastic tips on the ends of shoelaces. Like those tips, telomeres help protect chromosomes from becoming frayed and damaged. When DNA is damaged, normal cellular processes are disrupted and … Continue reading Telomere Length May Be Key to Earlier Detection of Pleural Mesothelioma
There is new evidence that low doses of the drug Opdivo (nivolumab) may extend lung cancer survival as well as the standard dose—at a much lower cost. The news may have implications for people with the lung-related asbestos cancer, malignant mesothelioma, who are also sometimes treated with Opdivo. Pleural mesothelioma is a hard-to-treat cancer that grows on the lining around the lungs and causes many of the same symptoms as lung cancer. Some evidence has suggested that Opdivo, an immunotherapy drug already approved for the treatment of recurrent lung cancer, may soon become the first drug approved for recurrent mesothelioma, too. Now, a newly-published Korean study finds that patients may not need as much of the drug as originally thought … Continue reading Opdivo for Malignant Mesothelioma: Could a Lower Dose Work?
Taiwanese cancer researchers say a total asbestos ban is “urgently needed” to help stem the tide of pleural mesothelioma cases predicted in the next 30 years. While the incidence of malignant mesothelioma has finally begun to level off in some countries, its incidence worldwide continues to grow. Taiwan is just one example of a country where mesothelioma rates, as well as the rates of other asbestos-related diseases (ARDs), are expected to keep climbing for at least another couple of years. Even after 2020, the authors of a new mesothelioma study say the disease will continue to be a problem for decades, highlighting the need for Taiwan to implement a total asbestos ban and devote more resources to mesothelioma screening, diagnosis, … Continue reading Hundreds of Mesothelioma Deaths Predicted for Taiwan
Recent research suggests that how people with lung cancers like pleural mesothelioma are treated by their oncology nurses can have a direct bearing on their treatment outcomes. The news is based on a groundbreaking study conducted at two Chinese universities and published in Psychology Research and Behavior Management. Empathy and Lung Cancer Survival The study focused on 365 lung cancer patients who were cared for by 30 different nurses at a Beijing hospital between October 2016 and May 2017. Researchers used a test called flow cytometry to measure the activity of cancer fighting immune system cells including T-cells, B-cells and natural killer (NK) cells. These cells are also activated in patients battling malignant mesothelioma and other cancers. This “cellular immunity” … Continue reading Nurse Compassion May Improve Mesothelioma Outcomes
There is some good news and some bad news this week for patients with malignant peritoneal mesothelioma, an aggressive form of cancer that occurs on the lining of the abdomen. Both come from a new article on peritoneal cancer published in the International Journal of Clinical Oncology. The good news is that most patients with peritoneal mesothelioma and other forms of cancer on the peritoneal membrane respond well to the multi-modal treatment regimen that has become the standard-of-care for this form of the asbestos cancer. A combination of cytoreductive surgery (CRS) and heated intraperitoneal chemotherapy (HIPEC) allows most peritoneal cancer patients to “achieve long-term disease-free survival”, according to the study from the National Cancer Centre Singapore. But the more disturbing … Continue reading New Study Examines Early Recurrence of Peritoneal Mesothelioma After Surgery
A new Japanese study has some sobering news for people hoping to survive malignant mesothelioma: Life after mesothelioma can still be challenging. The study was conducted by multiple centers across Japan. A total of 133 mesothelioma patients who had been free of disease for at least five years completed questionnaires about their experiences and their quality of life. Assessing the Lives of Mesothelioma Survivors To get a picture of what life is like for mesothelioma survivors, the study group sent a 64-question survey to hospitals and patient advocacy groups. Patients completed the questionnaire themselves and then returned it to the researchers by mail. The questions specifically about quality-of-life came from the European Organization for Research and Treatment of Cancer and the … Continue reading Life After Mesothelioma Can Still Be a Challenge
Carbon ion therapy—a cancer treatment developed in California but currently only available outside the US—may have the ability to significantly slow down the growth and spread of pleural mesothelioma tumors. Researchers at one of the world’s most experienced carbon ion therapy centers in Chiba, Japan shared that conclusion in a new article in the journal Oncotarget. According to the new research, carbon ion beams directed at two lines of malignant mesothelioma cells in the lab “suppressed cell viability”. The addition of cisplatin, one of two primary chemotherapy drugs used in the treatment of mesothelioma around the world, “significantly enhanced its action.” The news is likely to be both exciting and frustrating for American mesothelioma patients who do not yet have … Continue reading Hard-to-Find Therapy Fights Mesothelioma Tumors with Carbon Ions