A new study is shedding light on the psychological effects of mesothelioma on patients and their caregivers. Researchers at the University of Sheffield in the UK reviewed more than 35 years worth of medical literature to find relevant studies. They say the psychological effects of mesothelioma revolve around timelines, emotions, and communication. They also suggest that more should be done to understand the unique burdens of mesothelioma caregivers. Rarity of Mesothelioma May Impact the Psychological Effects Malignant mesothelioma is an aggressive cancer of internal membranes. It can be a lonely disease for caregivers and patients. Only about 2,500 Americans receive a mesothelioma diagnosis each year making it one of the rarest types of cancer. In many cases, a family may … Continue reading Understanding the Psychological Effects of Mesothelioma
A combination of ramucirumab (CYRAMZA) and gemcitabine creates a promising second-line mesothelioma treatment. New research shows the combination nearly doubled survival in a group of patients whose tumors kept growing with standard therapy. Italian researchers shared their findings at the virtual annual meeting of ASCO. ASCO is one of the largest gatherings of cancer doctors in the US. First-Line Mesothelioma Treatment Failure For most mesothelioma patients, chemotherapy with Alimta is the first-line treatment. This does keep the cancer in check for some patients. But after a while, mesothelioma tumors almost always come back. Chemotherapy only extends survival by about four months. Doctors have tested many different approaches to second-line mesothelioma treatment. Some of the therapies tested are: Additional rounds of … Continue reading Second-Line Mesothelioma Treatment with Ramucirumab
A newly published Croatian case illustrates how challenging it can sometimes be to distinguish between breast cancer and mesothelioma. The case involves a 61-year-old woman with what appeared to be breast cancer. Further study revealed that what the woman actually had was pleural mesothelioma. The mesothelioma had spread to her breast. Breast cancer and mesothelioma cells look similar under the microscope. But they are very different. The authors of the new report caution doctors against the “pitfall” of mistaking one for the other. Breast Metastasis is Rare Pleural mesothelioma occurs on the membrane that surrounds the lungs. It is rare for mesothelioma to spread to the breast. The most common place for mesothelioma cells to spread is the lungs. Women … Continue reading Breast Cancer and Mesothelioma: Case Study Illustrates Diagnostic Challenge
A new first-line mesothelioma treatment has moved a step closer to becoming reality. New data show that the immunotherapy drug ONCOS-102 continues to look promising, nine months into a Phase I/II clinical trial. The drug was especially helpful to mesothelioma patients who had not yet had any treatment. Norweigian drug maker Targovax made the announcement earlier this month. ONCOS-102 is an experimental drug based on a modified virus. The virus helps it target mesothelioma cells while leaving healthy cells alone. The latest results show ONCOS-102 helps standard mesothelioma chemotherapy work better. Targovax says the next step will be a larger test of the combination as a first-line mesothelioma treatment. Clinical Trial of ONCOS-102 The power of ONCOS-102 comes from the … Continue reading Could ONCOS-102 Be a New First-Line Mesothelioma Treatment?
Europe’s top mesothelioma experts have released new best practices for pleural mesothelioma. They include the latest recommendations on diagnosis, staging, monitoring, and treatment. The task force was made up of members from: European Respiratory Society (ERS) European Society of Thoracic Surgeons (ESTS) European Association for Cardio-Thoracic Surgery (EACTS) European Society for Radiotherapy and Oncology (ESTRO) This is the first time the best practices for pleural mesothelioma were updated since 2009. The group based the new recommendations on mesothelioma data gathered in the last decade. Mesothelioma Remains a Global Challenge Malignant mesothelioma is one of the world’s most challenging cancers. Doctors know that asbestos exposure causes mesothelioma. But many other things about this disease are a mystery. Some people with a … Continue reading Best Practices for Pleural Mesothelioma: Updated Recommendations from Europe’s Top Doctors
It may be harder this year for patients who need it to get surgery for peritoneal mesothelioma. An international group called RENAPE keeps track of peritoneal cancers like mesothelioma. The group advises doctors on the best treatment practices. The group is advising hospitals to tighten the criteria for who can get surgery for peritoneal mesothelioma during the pandemic. “The Covid-19 pandemic is profoundly changing the organization of healthcare access,” say French doctors writing about the RENAPE recommendations. “This is particularly so for peritoneal neoplastic diseases, for which curative treatment mobilizes substantial personnel, operating room and intensive care resources.” Mesothelioma Treatment Options Mesothelioma is a rare cancer associated with asbestos exposure. About a fifth of all mesothelioma cases are the peritoneal … Continue reading Surgery for Peritoneal Mesothelioma Could Be Limited During Pandemic
There is new evidence to support the idea that infections can help fight mesothelioma. Researchers at a Belgium University say mice with mesothelioma had slower-growing tumors and lived longer when they were injected with a virus. The research team used a mouse virus called lactate dehydrogenase-elevating virus. The new study suggests that infections can help fight mesothelioma by activating cancer-killing immune system cells. The study could help doctors understand how to use the immune system to combat malignant mesothelioma in human patients. The Immune System and Mesothelioma The immune system is constantly on the lookout for cells that could turn into cancer. When natural killer cells recognize a potential mesothelioma cell, they destroy it. But mesothelioma cells produce proteins that … Continue reading Infections Can Help Fight Mesothelioma, Study Suggests
After a mysterious cluster of mesothelioma cases cropped up among Italian textile workers, researchers found an unusual way of tracking asbestos exposure. Asbestos is the main cause of malignant mesothelioma. Many mesothelioma patients came in contact with asbestos at work. But it is not always clear how it happened. Mesothelioma legal cases often hinge on tracking asbestos exposure at a negligent company. But in the case of the Italian textile workers, the exposure was not obvious. The workers produced sewing threads. They did not work directly with asbestos. It was not until an abatement company started removing asbestos from the plant, that researchers got a clearer picture of why the workers got sick. The Challenge of Tracking Asbestos Exposure Asbestos … Continue reading Italian Case Illustrates Unusual Way of Tracking Asbestos Exposure
Swiss doctors have used a combination of photodynamic therapy and immunotherapy to dramatically shrink mesothelioma tumors in mice. More than a third of mice treated with an immune checkpoint inhibitor and low-dose light therapy experienced complete regression of their cancer. The new study explores how photodynamic therapy and immunotherapy can work together. The answers could have important implications for tens of thousands of people suffering from asbestos cancer. Two Different Approaches to Mesothelioma Mesothelioma is a rare but deadly cancer caused by asbestos exposure. Pleural mesothelioma occurs on the membrane around the lungs. It is the most common type of mesothelioma. Around 2,500 Americans receive a mesothelioma diagnosis each year. There is no cure. Photodynamic therapy and immunotherapy both show … Continue reading Photodynamic Therapy and Immunotherapy: A Powerful Mesothelioma Combo?
Italian cancer researchers have released new data on how patient location impacts mesothelioma therapy in the country. Pleural mesothelioma is a rare cancer. Most doctors see very few cases in the course of their careers. This lack of expertise may explain why the preferred treatments vary from one region to the next. Italy’s Scientific Institute for Research, Hospitalization and Healthcare led the new research. They analyzed pleural mesothelioma outcomes across the country. The conclusion is that location impacts mesothelioma therapy in Italy because there is not enough sharing of information. Choosing a Mesothelioma Treatment Approach Pleural mesothelioma is challenging to diagnose and even more difficult to treat. Even experienced mesothelioma doctors often struggle to know the best way to approach … Continue reading Research Shows Location Impacts Mesothelioma Therapy in Italy