Early Detection of Mesothelioma with MicroRNAs

Testing for Early Detection of Mesothelioma

A new study appears to contradict some of what scientists thought they knew about early detection of mesothelioma. Malignant mesothelioma is a rare but highly aggressive cancer. It usually happens because of past asbestos exposure. Early detection of mesothelioma is key to improving survival. But it is notoriously hard to make a mesothelioma diagnosis. Many patients who have mesothelioma do not even know it until the cancer is in its advanced stage. As a result, most do not live more than a year. Some studies have suggested that tiny, non-coding bits of RNA could help doctors detect mesothelioma earlier. But new research in Germany brings that idea into question. Biomarkers for Early Detection of Mesothelioma MicroRNAs (miRNAs) play an important … Continue reading Early Detection of Mesothelioma with MicroRNAs »

Asbestos in Mesothelioma Development: No Amount is Safe

asbestos in mesothelioma development

A new study contains some sobering news about the role of asbestos in mesothelioma development. Public health officials in Italy analyzed the medical records of people who died of pleural mesothelioma in the Broni, Italy area. Broni was the site of an asbestos cement plant from 1932 until 1993. They discovered that even some people who did not work with asbestos had a high risk of dying from this rare cancer. In fact, their risk for mesothelioma was higher even though their asbestos exposure was smaller. It suggests that no amount of asbestos exposure is “safe” — especially for people who are extra sensitive because of their genetics. Small Amounts of Asbestos in Mesothelioma Development Scientists began to suspect the … Continue reading Asbestos in Mesothelioma Development: No Amount is Safe »

Palliative Care for Mesothelioma: Earlier is Not Necessarily Better

palliative care for mesothelioma

New research suggests that palliative care for mesothelioma may be most helpful in later stages of the disease. Scientists in the UK and Australia say there is no reason for most mesothelioma patients to be referred to a palliative care specialist when they are diagnosed. As long as patients have access to palliative care when they need it, early referral does not seem to make much difference in quality of life. What is Palliative Care for Mesothelioma? Palliative care for mesothelioma aims to manage the symptoms of the disease and the treatment. Chest pain and shortness of breath are common symptoms of mesothelioma. Mesothelioma treatment can cause fatigue, nausea, and weight loss. Physical symptoms can cause depression or anxiety, which … Continue reading Palliative Care for Mesothelioma: Earlier is Not Necessarily Better »

BAP1 Can Distinguish Mesothelioma from Other Conditions

Scientist looking at mesothelioma cells

German scientists say a protein could help doctors distinguish mesothelioma from other conditions. Malignant mesothelioma is a cancer that grows on the membranes around organs. These membranes are called mesothelial membranes. But other conditions can also grow on mesothelial membranes. One of those conditions is adenomatoid tumors. Adenomatoid tumors are benign but, even under the microscope, their cells can look a lot like malignant mesothelioma. Now, a group of pathologists in Germany say the BAP1 protein can tell these two conditions apart. If doctors can distinguish mesothelioma from other conditions early enough, mesothelioma patients may have better outcomes. BAP1 Loss and Mesothelioma BAP1 is a protein encoded by the BAP1 gene. BAP1 is one of the proteins that helps keep … Continue reading BAP1 Can Distinguish Mesothelioma from Other Conditions »

Scientists Say Machine Learning Could Help Diagnose Mesothelioma Earlier

machine leaning might help diagnose mesothelioma earlier

Researchers in Toronto say machine learning could help doctors diagnose mesothelioma earlier. Molecular geneticists at the University of Toronto teamed up with cancer and heart doctors to conduct the new research. The team collected data from hundreds of suspected mesothelioma cases and ran it through different statistical analysis programs. The goal was to see which one was best at determining who had pleural mesothelioma and who did not. The results revealed some important information – both about the machine learning tools and about how doctors might diagnose mesothelioma earlier, even without them. Why Doctors Need to Diagnose Mesothelioma Earlier Mesothelioma is almost always caused by asbestos exposure. In the first few years of the disease, there may be no mesothelioma … Continue reading Scientists Say Machine Learning Could Help Diagnose Mesothelioma Earlier »

New Study Could Lead to a Mesothelioma Breath Test

breath test for mesothelioma

A large new study now underway may eventually make it possible to create a mesothelioma breath test. Cancer Research UK has launched a two-year clinical trial of the Breath Biopsy. The Breath Biopsy is a device that detects molecules exhaled by people with cancer. The Need for Early Mesothelioma Detection Malignant mesothelioma is one of the deadliest types of cancer. Most people who get mesothelioma have been exposed to asbestos. By the time they receive a diagnosis, many mesothelioma patients have advanced disease. Late diagnosis is one of the main reasons people with mesothelioma often die within a year. When mesothelioma cancer is in an advanced stage, it is less likely to respond to treatment. Scientists around the world are … Continue reading New Study Could Lead to a Mesothelioma Breath Test »

Chemotherapy for Mesothelioma May Work Better with TroVax

vaccine added to chemotherapy for mesothelioma

UK researchers say a cancer vaccine called Trovax has the potential to boost the power of chemotherapy for mesothelioma. Chemotherapy is the main treatment for malignant pleural mesothelioma. Mesothelioma is a cancer of the lung lining caused by asbestos exposure. It is very hard to treat. Even people who have chemotherapy for mesothelioma do not usually live more than two years after diagnosis. Mesothelioma researchers are always looking for ways to improve chemotherapy for mesothelioma. It is often combined with other treatments like surgery, radiation or immunotherapy. Now, scientists think adding TroVax to mesothelioma chemotherapy may be another good option. What is the TroVax Cancer Vaccine? The TroVax cancer vaccine is made by UK-based Oxford BioMedica. It contains an altered … Continue reading Chemotherapy for Mesothelioma May Work Better with TroVax »

Faster Mesothelioma Chemotherapy Deemed “Safe and Feasible”

faster mesothelioma chemotherapy

Researchers in The Netherlands say it may be possible to deliver faster mesothelioma chemotherapy without doing any additional damage to the kidneys. If they are right, it could make mesothelioma treatment more accessible and convenient for patients. Most malignant mesothelioma patients will have chemotherapy. The most common type of chemotherapy is by infusion. Each session takes several hours. Every mesothelioma patient undergoing chemotherapy faces the possibility of kidney damage. That possibility can even limit how much medicine doctors can use. But a new Dutch study finds that faster mesothelioma chemotherapy may be as safe for the kidneys as standard chemotherapy. Analyzing Faster Mesothelioma Chemotherapy The study included 230 lung cancer patients who had chemotherapy. Some of the study subjects had … Continue reading Faster Mesothelioma Chemotherapy Deemed “Safe and Feasible” »

Stress in Mesothelioma Patients During the Holidays

asbestos-exposed people stress

Every mesothelioma sufferer feels it, but there is very little data on emotional stress in mesothelioma patients and asbestos-exposed people. That is the conclusion of a group of Italian researchers earlier this year. The study is important to revisit during the holidays when mesothelioma patients may feel pressured to be cheerful. According to the Italian team, mesothelioma sufferers and asbestos-exposed people have some special emotional needs. The few studies that exist on the subject suggest that denying these problems may make people sicker. Studying the Studies The team found 12 studies published between 1980 and 2016 on stress in mesothelioma patients. The number of papers on the emotional needs of asbestos-exposed people was even lower. There were only nine of … Continue reading Stress in Mesothelioma Patients During the Holidays »

Combination Therapy with Mesothelioma Surgery Leads to Longer Survival

Mesothelioma surgery patient with nurse

A new study finds almost a quarter of people who had combination therapy with mesothelioma surgery were still alive five years later. The study was published in the European Journal of Cardio-Thoracic Surgery. Researchers at University Hospitals KU Leuven in Belgium studied nearly 200 mesothelioma patients from 2003 to 2014. Many people do not live beyond about 18 months after a mesothelioma diagnosis. But the Belgian team says, for the right patients, there is a way to improve the odds. They say combination therapy with radical mesothelioma surgery offers a 1 in 4 chance of surviving for 5 years or more. Two Types of Mesothelioma Surgery There are two major schools of thought about mesothelioma surgery. Some surgeons say it … Continue reading Combination Therapy with Mesothelioma Surgery Leads to Longer Survival »

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