MicroRNA Signature for Mesothelioma Could Lead to Earlier Diagnosis

microRNA signature for mesothelioma

Australian researchers believe they have identified what amounts to a microRNA signature for mesothelioma in pleural effusion.  Pleural effusion is the name for excess lung fluid. Up to 90 percent of pleural mesothelioma patients develop a pleural effusion. Researchers at the University of Western Australia say this fluid contains a wealth of information that could improve mesothelioma diagnosis. They have recently identified a trio of RNA molecules in fluid samples that could serve as a microRNA signature for mesothelioma. This “signature” could help doctors distinguish mesothelioma from other types of cancer. The Challenge of Mesothelioma Diagnosis Pleural mesothelioma is notoriously hard to diagnose. The early symptoms of mesothelioma are similar to the symptoms of many other lung conditions. They are … Continue reading MicroRNA Signature for Mesothelioma Could Lead to Earlier Diagnosis »

Minimally Invasive Lymph Node Staging May Prevent Unnecessary Mesothelioma Surgery

lymph node staging for mesothelioma

A minimally invasive procedure for lymph node staging may help some pleural mesothelioma patients avoid the pain and risk of surgery. That is the conclusion of a recent study on endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA).  EBUS-TBNA is a minimally invasive method for testing the lymph nodes deep in the chest (mediastinal lymph nodes). If lymph node staging shows evidence of pleural mesothelioma, surgery is less likely to be effective.  Mediastinal Lymph Node Staging and Mesothelioma Pleural mesothelioma is a rare cancer that starts on the membrane around the lungs. It can spread to the lungs and other organs and is usually fatal.  The mediastinal lymph nodes are located in the area between the lungs. When the body is fighting … Continue reading Minimally Invasive Lymph Node Staging May Prevent Unnecessary Mesothelioma Surgery »

Evaluating Mesothelioma Symptoms: New Tool Makes it Easier

evaluating mesothelioma symptoms

Evaluating mesothelioma symptoms is an important step in planning treatment for asbestos cancer. But researchers at a top US cancer center say it is hard to do a thorough job using current tools. That’s why doctors at MD Anderson have developed their own method for evaluating mesothelioma symptoms. They made some mesothelioma-specific additions to an existing cancer symptom evaluation system. Tests on more than 200 mesothelioma patients show the method works well and is easy to use. The developers hope doctors can use it to design better mesothelioma treatment plans. The Importance of Evaluating Mesothelioma Symptoms When a patient receives a mesothelioma diagnosis, the next step is evaluating mesothelioma symptoms. This process can help give the doctor valuable information about … Continue reading Evaluating Mesothelioma Symptoms: New Tool Makes it Easier »

Breath Testing for Mesothelioma: Not Yet Ready for Widespread Use?

breath testing for mesothelioma

Breath testing for mesothelioma may be a promising new way to catch asbestos cancer early. But Italian researchers are warning that there is not yet enough research to recommend widespread use of the technique. Malignant pleural mesothelioma is a virulent and hard-to-treat cancer. Researchers around the world continue to search for faster, easier ways to diagnose and treat it. Breath testing for mesothelioma is one proposed method. Special machines measure volatile organic compounds (VOCs) in patients’ exhaled breath. VOCs can give doctors important information about cellular metabolism and can indicate the presence of cancer. But researchers at Italy’s University of Bari analyzed all of the studies on breath testing for mesothelioma since 2000. They say none of the studies are … Continue reading Breath Testing for Mesothelioma: Not Yet Ready for Widespread Use? »

Machine Learning Could Lead to Earlier Mesothelioma Diagnosis

earlier mesothelioma diagnosis

A machine learning tool being developed by Google could lead to earlier mesothelioma diagnosis and better survival rates. That word comes from Google artificial intelligence experts who recently presented their research at a developer conference in California. Machine learning specialist Lily Peng told the gathering that advanced A.I. can detect lung cancers like mesothelioma before doctors can even see them. Earlier mesothelioma diagnosis would allow for earlier intervention which could mean longer survival for victims of one of the world’s deadliest cancers. Diagnosis Often Comes Too Late Mesothelioma is a form of lung cancer caused by asbestos exposure. It can take decades to develop, but It is usually fatal within 18 months of diagnosis. One reason is that earlier mesothelioma … Continue reading Machine Learning Could Lead to Earlier Mesothelioma Diagnosis »

Scientists Say Machine Learning Could Help Diagnose Mesothelioma Earlier

machine leaning might help diagnose mesothelioma earlier

Researchers in Toronto say machine learning could help doctors diagnose mesothelioma earlier. Molecular geneticists at the University of Toronto teamed up with cancer and heart doctors to conduct the new research. The team collected data from hundreds of suspected mesothelioma cases and ran it through different statistical analysis programs. The goal was to see which one was best at determining who had pleural mesothelioma and who did not. The results revealed some important information – both about the machine learning tools and about how doctors might diagnose mesothelioma earlier, even without them. Why Doctors Need to Diagnose Mesothelioma Earlier Mesothelioma is almost always caused by asbestos exposure. In the first few years of the disease, there may be no mesothelioma … Continue reading Scientists Say Machine Learning Could Help Diagnose Mesothelioma Earlier »

New Study Could Lead to a Mesothelioma Breath Test

breath test for mesothelioma

A large new study now underway may eventually make it possible to create a mesothelioma breath test. Cancer Research UK has launched a two-year clinical trial of the Breath Biopsy. The Breath Biopsy is a device that detects molecules exhaled by people with cancer. The Need for Early Mesothelioma Detection Malignant mesothelioma is one of the deadliest types of cancer. Most people who get mesothelioma have been exposed to asbestos. By the time they receive a diagnosis, many mesothelioma patients have advanced disease. Late diagnosis is one of the main reasons people with mesothelioma often die within a year. When mesothelioma cancer is in an advanced stage, it is less likely to respond to treatment. Scientists around the world are … Continue reading New Study Could Lead to a Mesothelioma Breath Test »

Japanese Discovery Could Lead to New Mesothelioma Blood Test

mesothelioma blood test

A discovery in Japan could lead to a more effective mesothelioma blood test for mesothelioma diagnosis. Japanese scientists say they have found a better way to detect mesothelioma cells in the blood.  The scientists are experts in occupational health. Malignant mesothelioma is an occupational cancer because people can get it from working near asbestos. Mesothelioma diagnosis is challenging. But a powerful mesothelioma blood test could make it easier to find the asbestos cancer earlier. Treatment often works better when patients start it earlier. Circulating Tumor Cells in the Blood of Mesothelioma Patients No matter what kind of cancer a person has, their tumor releases some cells into the blood. Mesothelioma tumors are no exception. These circulating tumor cells (CTCs) are … Continue reading Japanese Discovery Could Lead to New Mesothelioma Blood Test »

This Subset of Mesothelioma Patients May Live Longer

A group of mesothelioma experts from around the world has identified a set of criteria linked with longer mesothelioma survival. They are hopeful that their research will help doctors identify mesothelioma patients who fall into this longer-living group and direct them to the special care they may need to stay healthier, longer. In a new article in the Journal of Clinical Oncology, some of the world’s leading mesothelioma researchers, including scientists from Stanford University, New York University Langone Medical Center, The University of Hawaii, the Hyogo College of Medicine in Japan, and the Mesothelioma Applied Research Foundation, say mesothelioma patients who meet these criteria should consider genetic counseling and cancer screening. Criteria for Improved Mesothelioma Outcomes The report was based … Continue reading This Subset of Mesothelioma Patients May Live Longer »

New Data Suggest a Mesothelioma Blood Test is Possible

A new technology that looks for genetic material from cancer cells in the blood could open the door to the fastest, easiest way yet to diagnose early malignant pleural mesothelioma. The test, which has already shown potential for early detection of lung cancer, was developed by a California-based life sciences company called GRAIL. GRAIL-funded researchers shared the data on the test at the American Society of Clinical Oncology annual meeting this summer in Chicago. The results are part of the preliminary data from the company’s ongoing Circulating Cell-Free Genome Atlas study, a huge study on cancer diagnosis that aims to enroll 15,000 people (70 percent with cancer and 30 percent without) from 141 sites in the US and Canada. “We’re … Continue reading New Data Suggest a Mesothelioma Blood Test is Possible »

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