This Subset of Mesothelioma Patients May Live Longer

A group of mesothelioma experts from around the world has identified a set of criteria linked with longer mesothelioma survival. They are hopeful that their research will help doctors identify mesothelioma patients who fall into this longer-living group and direct them to the special care they may need to stay healthier, longer. In a new article in the Journal of Clinical Oncology, some of the world’s leading mesothelioma researchers, including scientists from Stanford University, New York University Langone Medical Center, The University of Hawaii, the Hyogo College of Medicine in Japan, and the Mesothelioma Applied Research Foundation, say mesothelioma patients who meet these criteria should consider genetic counseling and cancer screening. Criteria for Improved Mesothelioma Outcomes The report was based … Continue reading This Subset of Mesothelioma Patients May Live Longer »

New Data Suggest a Mesothelioma Blood Test is Possible

A new technology that looks for genetic material from cancer cells in the blood could open the door to the fastest, easiest way yet to diagnose early malignant pleural mesothelioma. The test, which has already shown potential for early detection of lung cancer, was developed by a California-based life sciences company called GRAIL. GRAIL-funded researchers shared the data on the test at the American Society of Clinical Oncology annual meeting this summer in Chicago. The results are part of the preliminary data from the company’s ongoing Circulating Cell-Free Genome Atlas study, a huge study on cancer diagnosis that aims to enroll 15,000 people (70 percent with cancer and 30 percent without) from 141 sites in the US and Canada. “We’re … Continue reading New Data Suggest a Mesothelioma Blood Test is Possible »

Mesothelioma Genetic “Fingerprint” Could Impact Compensation

A new report suggests that it may be possible to verify that a case of lung cancer or malignant mesothelioma was caused by exposure to asbestos. The key may lie in tiny cellular structures called  microRNAs. If the microRNA asbestos profile can be verified, it could have a significant impact on work-related compensation for pleural mesothelioma and asbestos-related lung cancer. The Molecular “Fingerprint” of Mesothelioma? MicroRNAs (miRNAs) are small non-coding molecules of RNA that play a key role in the regulation of gene expression in cells. When these miRNAs are out of balance or “overexpressed”, the result can be cancer. By examining the miRNAs of mesothelioma patients, lung cancer patients, and healthy subjects, researchers at Marche Polytechnic University in Ancona, Italy … Continue reading Mesothelioma Genetic “Fingerprint” Could Impact Compensation »

Mesothelioma Surgery and the Threat of Opioid Addiction

A new study of opioid addiction among lung cancer patients may have implications for pleural mesothelioma patients who are considering surgery. The study, published this month in JAMA Oncology, finds that patients treated with more invasive surgical techniques are more likely to become chronic opioid users than those who have less invasive surgery. Opioids Are ‘Standard of Care’ for Lung Surgery Patients Researchers at Mount Sinai Medical Center in New York studied the cases of nearly 4,000  people from the SEER Medicare database who had some type of surgery for non-small cell lung cancer, a type of cancer that shares many commonalities with the lung-related asbestos cancer, pleural mesothelioma. Some of the lung cancer patients studied underwent open thoracic surgery while others … Continue reading Mesothelioma Surgery and the Threat of Opioid Addiction »

Advanced Computer Program Might Pinpoint Mesothelioma Sooner

Scientists at New York University School of Medicine have successfully used a sophisticated computer program to distinguish between different types of lung cancer and identify the mutated genes behind them. The developers say the technology could open the door to faster diagnosis of other types of cancer, including malignant mesothelioma. Malignant Mesothelioma, the Asbestos Cancer Malignant pleural mesothelioma is a form of lung cancer caused by asbestos exposure. Instead of starting in the lung tissue like other types of lung cancer, it grows on the membrane that surrounds the lungs and can then spread to the lungs and other organs. There is no cure and the prognosis for mesothelioma is usually poor. As with most types of cancer, earlier diagnosis … Continue reading Advanced Computer Program Might Pinpoint Mesothelioma Sooner »

Telomere Length May Be Key to Earlier Detection of Pleural Mesothelioma

Japanese pathologists have a new theory that may lead to earlier detection and better outcomes for people with malignant pleural mesothelioma. Researchers led by the International University of Health and Welfare in Tokyo say exposure to asbestos appears to shorten the telomeres that protect the ends of DNA strands. The discovery could give doctors another way to diagnose malignant mesothelioma in time to implement more effective treatments. What are Telomeres? Telomeres are the caps on the end of each strand of DNA. According to Telomere Activation Sciences, telomeres function like the plastic tips on the ends of shoelaces. Like those tips, telomeres help protect chromosomes from becoming frayed and damaged. When DNA is damaged, normal cellular processes are disrupted and … Continue reading Telomere Length May Be Key to Earlier Detection of Pleural Mesothelioma »

Penn Surgeons “Light Up” Tumors to Boost Mesothelioma Survival

University of Pennsylvania surgeons are experimenting with a new technology that could vastly improve survival for patients with malignant pleural mesothelioma by ensuring that more of their cancer can be  removed. Complete resection of mesothelioma tumors can be the difference between life and death; even a few cancer cells left behind can quickly grow into new tumors. But macroscopic complete resection, as it is called, is not easy. Not only are mesothelioma tumors irregularly-shaped and located close to critical organs like the lungs and heart, but surgeons say it is often hard to distinguish tiny metastatic tumors from inflammation or scar tissue. In addition, traditional scanning techniques like PET can’t usually show nodules smaller than a centimeter and can’t distinguish … Continue reading Penn Surgeons “Light Up” Tumors to Boost Mesothelioma Survival »

CT Discovery May Lead to Earlier Mesothelioma Diagnosis

Detecting Mesothelioma with New CT Algorithm

Researchers in Western Australia believe they may have found a way to overcome one of the biggest challenges in the management of malignant pleural mesothelioma—making the diagnosis earlier. Malignant mesothelioma is a fast-growing cancer that starts on the membrane, or pleura, that surrounds the lungs. Because the seeds for this disease can exist for decades before symptoms develop, and because the early symptoms of mesothelioma tend to be vague and similar to those of other conditions, the so-called “asbestos cancer” often goes undetected until it is in an advanced stage. As a result, the survivability of this disease is typically very low. But scientists at the University of Western Australia in Perth say there may be a simple way to … Continue reading CT Discovery May Lead to Earlier Mesothelioma Diagnosis »

New Pill Could Make Mesothelioma Diagnosis Easier, More Accurate

A pill that makes cancer cells glow under infrared light may have the capacity to improve the diagnosis of malignant mesothelioma. So far, the pill, being developed by researchers at the University of MIchigan with funding from the NIH, has only been tested on breast cancer tumors in mice. But it was so effective at exposing hidden clusters of cancer cells, that the research team expects it to be useful in the diagnosis of other cancers, too. That could eventually include mesothelioma. The Urgent Need for Earlier Mesothelioma Diagnosis Mesothelioma, a fast-growing cancer caused by asbestos exposure, is diagnosed in about 2,500 new patients in the US each year. About 2,000 of them have pleural mesothelioma, the most common type. … Continue reading New Pill Could Make Mesothelioma Diagnosis Easier, More Accurate »

New Technology Could Change How Mesothelioma Treatment is Monitored

New technology could eventually make it easier, less painful, and less expensive to track the progress of patients undergoing treatment for malignant mesothelioma and other cancers. A research team led by University of Wisconsin-Madison pharmacy professor Seungpyo Hong has developed what they say is a more efficient method for capturing free-floating cancer cells in the blood. The developers say the system is far more effective than existing systems at capturing these hard-to-find circulating tumor cells (CTCs) and could be used to supplement other technologies for tracking cancer treatment. Mesothelioma Biopsy vs CTC Tracking Although mesothelioma therapies have advanced in recent years, there is still no cure for the asbestos-linked cancer. As scientists work to develop new kinds of treatments like … Continue reading New Technology Could Change How Mesothelioma Treatment is Monitored »

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