Advanced Computer Program Might Pinpoint Mesothelioma Sooner

Scientists at New York University School of Medicine have successfully used a sophisticated computer program to distinguish between different types of lung cancer and identify the mutated genes behind them. The developers say the technology could open the door to faster diagnosis of other types of cancer, including malignant mesothelioma. Malignant Mesothelioma, the Asbestos Cancer Malignant pleural mesothelioma is a form of lung cancer caused by asbestos exposure. Instead of starting in the lung tissue like other types of lung cancer, it grows on the membrane that surrounds the lungs and can then spread to the lungs and other organs. There is no cure and the prognosis for mesothelioma is usually poor. As with most types of cancer, earlier diagnosis … Continue reading Advanced Computer Program Might Pinpoint Mesothelioma Sooner »

Telomere Length May Be Key to Earlier Detection of Pleural Mesothelioma

Japanese pathologists have a new theory that may lead to earlier detection and better outcomes for people with malignant pleural mesothelioma. Researchers led by the International University of Health and Welfare in Tokyo say exposure to asbestos appears to shorten the telomeres that protect the ends of DNA strands. The discovery could give doctors another way to diagnose malignant mesothelioma in time to implement more effective treatments. What are Telomeres? Telomeres are the caps on the end of each strand of DNA. According to Telomere Activation Sciences, telomeres function like the plastic tips on the ends of shoelaces. Like those tips, telomeres help protect chromosomes from becoming frayed and damaged. When DNA is damaged, normal cellular processes are disrupted and … Continue reading Telomere Length May Be Key to Earlier Detection of Pleural Mesothelioma »

Penn Surgeons “Light Up” Tumors to Boost Mesothelioma Survival

University of Pennsylvania surgeons are experimenting with a new technology that could vastly improve survival for patients with malignant pleural mesothelioma by ensuring that more of their cancer can be  removed. Complete resection of mesothelioma tumors can be the difference between life and death; even a few cancer cells left behind can quickly grow into new tumors. But macroscopic complete resection, as it is called, is not easy. Not only are mesothelioma tumors irregularly-shaped and located close to critical organs like the lungs and heart, but surgeons say it is often hard to distinguish tiny metastatic tumors from inflammation or scar tissue. In addition, traditional scanning techniques like PET can’t usually show nodules smaller than a centimeter and can’t distinguish … Continue reading Penn Surgeons “Light Up” Tumors to Boost Mesothelioma Survival »

CT Discovery May Lead to Earlier Mesothelioma Diagnosis

Detecting Mesothelioma with New CT Algorithm

Researchers in Western Australia believe they may have found a way to overcome one of the biggest challenges in the management of malignant pleural mesothelioma—making the diagnosis earlier. Malignant mesothelioma is a fast-growing cancer that starts on the membrane, or pleura, that surrounds the lungs. Because the seeds for this disease can exist for decades before symptoms develop, and because the early symptoms of mesothelioma tend to be vague and similar to those of other conditions, the so-called “asbestos cancer” often goes undetected until it is in an advanced stage. As a result, the survivability of this disease is typically very low. But scientists at the University of Western Australia in Perth say there may be a simple way to … Continue reading CT Discovery May Lead to Earlier Mesothelioma Diagnosis »

New Pill Could Make Mesothelioma Diagnosis Easier, More Accurate

A pill that makes cancer cells glow under infrared light may have the capacity to improve the diagnosis of malignant mesothelioma. So far, the pill, being developed by researchers at the University of MIchigan with funding from the NIH, has only been tested on breast cancer tumors in mice. But it was so effective at exposing hidden clusters of cancer cells, that the research team expects it to be useful in the diagnosis of other cancers, too. That could eventually include mesothelioma. The Urgent Need for Earlier Mesothelioma Diagnosis Mesothelioma, a fast-growing cancer caused by asbestos exposure, is diagnosed in about 2,500 new patients in the US each year. About 2,000 of them have pleural mesothelioma, the most common type. … Continue reading New Pill Could Make Mesothelioma Diagnosis Easier, More Accurate »

New Technology Could Change How Mesothelioma Treatment is Monitored

New technology could eventually make it easier, less painful, and less expensive to track the progress of patients undergoing treatment for malignant mesothelioma and other cancers. A research team led by University of Wisconsin-Madison pharmacy professor Seungpyo Hong has developed what they say is a more efficient method for capturing free-floating cancer cells in the blood. The developers say the system is far more effective than existing systems at capturing these hard-to-find circulating tumor cells (CTCs) and could be used to supplement other technologies for tracking cancer treatment. Mesothelioma Biopsy vs CTC Tracking Although mesothelioma therapies have advanced in recent years, there is still no cure for the asbestos-linked cancer. As scientists work to develop new kinds of treatments like … Continue reading New Technology Could Change How Mesothelioma Treatment is Monitored »

Breath​ ​Test​ ​May​ ​Finally​ ​Offer​ ​a​ ​Way​ ​to​ ​Screen​ ​for​ ​Pleural​ ​Mesothelioma

Earlier diagnosis of malignant pleural mesothelioma may be just a breath away. A new Belgian study shows that two kinds of breath-analyzing tests may finally offer an accurate way to screen for the deadly asbestos cancer. An accurate screening tool could lead to earlier mesothelioma diagnosis, earlier intervention, and, potentially, better treatment outcomes. Pleural mesothelioma is an extremely rare but aggressive cancer caused almost exclusively by exposure to asbestos fibers. Most people encounter these fibers in a work environment and most have no idea they are sick until mesothelioma is in an advanced stage and the odds of survival are slim. Although there are diagnostic tools that identify biomarkers in the blood or lung fluid of people with mesothelioma symptoms, … Continue reading Breath​ ​Test​ ​May​ ​Finally​ ​Offer​ ​a​ ​Way​ ​to​ ​Screen​ ​for​ ​Pleural​ ​Mesothelioma »

New Assessment Identifies People at High Risk for Malignant Mesothelioma

Black American Patient

Scottish researchers say they have come up with a better way to decide which asbestos-exposed people might benefit from mesothelioma screening or even mesothelioma prevention measures. They have developed an assessment tool to gather detailed information from workers about the time, duration, and nature of their asbestos exposure in order to better quantify their mesothelioma risk. “The assessment is based on the tasks carried out and includes parameters for substance emission potential, activity emission potential, the effectiveness of any local control measures, passive emission, the fractional time the asbestos source is active, and the efficiency of any respiratory protection worn,” writes lead author John W, Cherrie with the Institute of Occupational Medicine in Edinburgh. Measuring Asbestos Exposure Asbestos is the … Continue reading New Assessment Identifies People at High Risk for Malignant Mesothelioma »

A Breath Test for Mesothelioma?

Researchers in Belgium say a breath analysis tool could provide the next big breakthrough in the effort to diagnose malignant mesothelioma earlier. The team, made up of scientists from Ghent and Antwerp Universities, says the technique looks “very promising” and fits well within the aims of the “National Cancer Moonshot” research initiative established by President Obama. The Challenge of Mesothelioma Diagnosis Malignant pleural mesothelioma (MPM) is a rare, lung-related cancer linked to asbestos exposure. Although scientists have identified several compounds or “biomarkers” in blood or lung fluid that seem to be overproduced by mesothelioma tumors, these markers are not reliable enough to use as stand-alone diagnostic tools. Instead, they are currently used in conjunction with other diagnostic tools such as … Continue reading A Breath Test for Mesothelioma? »

Cellular Factors Predict Survival in Epithelioid Mesothelioma Patients

A team of French scientists believe they have found a way to predict survival and help plan a treatment course for people with the epithelioid form of malignant pleural mesothelioma. Until now, mesothelioma histological subtype has been the only way to reliably predict mesothelioma prognosis based on pathology (cellular characteristics that can be seen under a microscope). But mesothelioma researchers at the University Hospital of Saint Etienne have identified several  subtle differences between epithelioid mesothelioma cells from different patients that may have an impact on their treatment outcomes. Histopathology and Mesothelioma Prognosis Histopathology is the study of changes in tissue caused by disease. In the case of pleural mesothelioma, exposure to asbestos can cause the healthy cells in a person’s … Continue reading Cellular Factors Predict Survival in Epithelioid Mesothelioma Patients »

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