Eating to Beat Mesothelioma: New Study Sheds Light on Diet/Cancer Link
A new study on the link between diet and cancer contains important information for patients trying to beat mesothelioma. The study was conducted by researchers at Tufts University and published this week in JNCI Cancer Spectrum. It compares American diets and rates of several kinds of cancer in 2015. The goal was to determine how many cancer cases might be blamed on poor diet. Although the study did not focus on mesothelioma cancer, patients determined to beat mesothelioma would be wise to take note of the findings. Poor Nutrition Can Lead to Cancer The Tufts researchers estimated that more than 80,000 cases of cancer diagnosed in 2015 happened because of suboptimal diet. That is more than 5 percent of all … Continue reading Eating to Beat Mesothelioma: New Study Sheds Light on Diet/Cancer Link
Ofev Shelved as a Treatment for Pleural Mesothelioma
It is official – the VEGF inhibitor Ofev is out of the running as a treatment for pleural mesothelioma. Hopes had been high for this drug after initial results showed a survival advantage. For the last two years, Ofev (nintedanib) was the subject of a large, international clinical trial. But now the leaders of that trial have published their Phase III trial results in The Lancet: Respiratory Medicine. They show that Ofev did not extend survival and is not an effective treatment for pleural mesothelioma. Why Hopes Were High for Ofev Ofev is an oral medication that stops cancer cells from producing a protein called VEGF. VEGF promotes the growth of blood vessels that help mesothelioma tumors grow. VEGF may … Continue reading Ofev Shelved as a Treatment for Pleural Mesothelioma
Machine Learning Could Lead to Earlier Mesothelioma Diagnosis
A machine learning tool being developed by Google could lead to earlier mesothelioma diagnosis and better survival rates. That word comes from Google artificial intelligence experts who recently presented their research at a developer conference in California. Machine learning specialist Lily Peng told the gathering that advanced A.I. can detect lung cancers like mesothelioma before doctors can even see them. Earlier mesothelioma diagnosis would allow for earlier intervention which could mean longer survival for victims of one of the world’s deadliest cancers. Diagnosis Often Comes Too Late Mesothelioma is a form of lung cancer caused by asbestos exposure. It can take decades to develop, but It is usually fatal within 18 months of diagnosis. One reason is that earlier mesothelioma … Continue reading Machine Learning Could Lead to Earlier Mesothelioma Diagnosis
Mesothelioma Quality of Life Improves After Surgery
New research confirms that surgery followed by HIPEC improves mesothelioma quality of life for people with peritoneal disease. Every mesothelioma surgery carries risks and can cause serious side effects. These problems often have a negative impact on mesothelioma quality of life in the short term. But researchers at Wake Forest University say cytoreductive surgery followed by intraperitoneal chemotherapy (HIPEC) boosts life quality for most mesothelioma patients over time. Evolving Management of Peritoneal Mesothelioma Malignant mesothelioma is a fast-growing cancer with a very low cure rate. Peritoneal mesothelioma accounts for about a fifth of all mesothelioma cases. With peritoneal mesothelioma, tumors start on the membrane that surrounds the abdominal organs and can spread to other parts of the body. Fatigue, pain, … Continue reading Mesothelioma Quality of Life Improves After Surgery
Palliative Radiotherapy for Mesothelioma Produces “Substantial Treatment Response”
Doctors in Pennsylvania may have found a way to boost the effectiveness of palliative radiotherapy for pleural mesothelioma. Palliative radiotherapy is used to help with mesothelioma symptoms. It uses lower doses of radiation. Doctors do not expect to treat mesothelioma with palliative radiotherapy. But researchers at the University of Pennsylvania think it could also be a treatment. They combined palliative radiotherapy with a special kind of gene therapy. The gene therapy affects the immune system. They say the combination produced a “substantial treatment response” in a man with mesothelioma. Immuno-gene Therapy and Palliative Radiotherapy Immuno-gene therapy uses genes to stimulate the immune system against cancer. In the new Pennsylvania case study, a 67-year-old man with mesothelioma received immuno-gene therapy. Doctors … Continue reading Palliative Radiotherapy for Mesothelioma Produces “Substantial Treatment Response”
Chemoimmunotherapy Called “Next Frontier” for Mesothelioma Cancer
Mesothelioma researchers in Australia are calling the combination of chemotherapy and immunotherapy the “next frontier” in the treatment of mesothelioma cancer. In a study published in the journal Expert Opinions in Biological Therapy, the researchers reviewed past clinical trials on mesothelioma immunotherapy. They focused on studies published between 2016 and 2018. Their goal was to get a clearer picture of just how effective these drugs are and how they might be used in combination with other treatments. Chemotherapy for Mesothelioma Cancer Currently, immunotherapy is not the primary treatment for mesothelioma cancer. Instead, most patients have chemotherapy, which is considered the gold standard treatment. For the past 15 years, Alimta has been the main chemotherapy drug for people with malignant mesothelioma. … Continue reading Chemoimmunotherapy Called “Next Frontier” for Mesothelioma Cancer
Flaxseed Compound May Help Prevent Malignant Mesothelioma and Asbestosis
There is new evidence that a compound found in flaxseeds may help prevent malignant mesothelioma and other asbestos-related diseases. The compound is an anti-inflammatory which appears to calm down the overactive immune system after asbestos exposure in mice. Inflammation has long been considered a key factor in the development of mesothelioma. Scientists are hopeful that preventing it may also prevent malignant mesothelioma. Inflammatory Response to Asbestos Exposure Asbestos is a group of naturally-occuring minerals that cause cancer in people and animals. When a person accidentally breathes in or swallows asbestos fibers, they trigger an inflammatory response that can last for years. White blood cells flock to the area and damaging free radicals are produced. Over time, some cells may become … Continue reading Flaxseed Compound May Help Prevent Malignant Mesothelioma and Asbestosis
Many Elderly Mesothelioma Patients Get No Treatment
The majority of elderly mesothelioma patients are observed rather than treated and this can have a negative impact on their survival. That is the finding of a new study published in the Annals of Surgical Oncology. The study included more than 4,500 mesothelioma patients. Less than a quarter of these patients received any treatment for their mesothelioma. As a result, most of these patients lived less than six months. Treatment Options for Elderly Mesothelioma Patients Exposure to asbestos causes pleural mesothelioma. It can take decades after exposure for mesothelioma symptoms to occur. The median age for a malignant pleural mesothelioma diagnosis is 72. The older a patient is at diagnosis, the more likely they are to have other health problems. … Continue reading Many Elderly Mesothelioma Patients Get No Treatment
Lower-Volume Centers Less Likely to Follow Mesothelioma Treatment Guidelines
Mesothelioma patients need to beware of low-volume centers that are less likely to follow mesothelioma treatment guidelines. That is the message from a new study based on data from the National Cancer Institute. The study was run by doctors at Cedars-Sinai Medical Center in Los Angeles. It shows that treatment centers that do not see a lot of mesothelioma cases are less likely to follow the life-saving mesothelioma treatment guidelines. As a result, patients treated in these lower-volume facilities tend to have shorter mesothelioma survival. What are the Mesothelioma Treatment Guidelines? Malignant pleural mesothelioma is a cancer that occurs on the membrane that surrounds the lungs. It is extremely rare and difficult to treat. Many hospitals and doctors never see … Continue reading Lower-Volume Centers Less Likely to Follow Mesothelioma Treatment Guidelines
Study Highlights How Genes Impact Mesothelioma Survival
A new National Cancer Institute study shines a light on some of the ways genes impact mesothelioma survival. It could have important implications for mesothelioma treatment. The study was led by prominent mesothelioma researcher Raffit Hassan, MD. It focused on genetic mutations that may make certain mesothelioma patients more sensitive to chemotherapy. Genes, Genotype, and Mesothelioma Treatment A mesothelioma patient’s unique collection of genes, including genetic mutations, is known as their genotype. Genes impact mesothelioma survival in a variety of ways. Tumor suppressor genes are supposed to help keep tumors from forming. People with mutations on these genes may be more likely to get malignant mesothelioma. Other genes influence the cancer’s ability to “hide” from detection by the immune system. … Continue reading Study Highlights How Genes Impact Mesothelioma Survival
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