Stronger Mesothelioma Clinical Trials for Better Results
A commentary by an international team of researchers raises some concerns about how clinical cancer trials are conducted. The authors of the commentary hail from Israel, Italy, Ireland, and the United States. They claim that there is a need for better balance between the cost of new cancer drugs and their actual benefit to patients. The authors came to this conclusion after analyzing clinical trials for treatments for pleural mesothelioma. Gold Standard for Mesothelioma Treatments Mesothelioma is a rare form of cancer. It most often appears in older adults and is caused by exposure to asbestos. Asbestos is a toxic material that can be found in industrial and consumer products. Malignant pleural mesothelioma is a specific type of mesothelioma. It … Continue reading Stronger Mesothelioma Clinical Trials for Better Results
Mesothelioma Breakthrough Can Spare the Diaphragm
A new study shows that surgery for malignant pleural mesothelioma can spare the diaphragm without reducing overall survival. This study was conducted by medical researchers from St. Bartholomew’s Hospital in the United Kingdom. Surgery for Malignant Pleural Mesothlioma Mesothelioma is a type of cancer caused by exposure to asbestos. It can take decades after asbestos exposure for the cancer to develop. It is an aggressive cancer and can be hard to treat. When the cancer grows in your lungs, it is called malignant pleural mesothelioma (MPM). Conventional treatment for MPM may include surgery, radiation therapy, and chemotherapy. Surgery is the most invasive treatment option and not every patient is eligible for surgery. If the patient is too ill or if … Continue reading Mesothelioma Breakthrough Can Spare the Diaphragm
Surgery for Mesothelioma: Goals and Side Effects
Residual thoracic spaces occur in one-third of patients who receive surgery for mesothelioma. This is the space left after mesothelioma disease is removed from the lung. A new study by researchers in Japan details the results of an analysis of this side effect. Pleural Mesothelioma Mesothelioma is a rare form of cancer caused by exposure to asbestos. Treatment often combines surgery, chemotherapy, and radiation. Pleural mesothelioma is a type of cancer that develops from the thin layer of tissue that covers the lungs and chest wall. Symptoms may include shortness of breath due to fluid around the lung, chest pain, cough, and fatigue. This cancer is caused by exposure to asbestos. It can often take around 40 years for pleural … Continue reading Surgery for Mesothelioma: Goals and Side Effects
Neoadjuvant Chemotherapy Offers Safe Treatment for Mesothelioma
Neoadjuvant chemotherapy is a safe treatment option for patients with mesothelioma. That is the finding of a study from a team of researchers from the University of Pennsylvania. The researchers analyzed the records of 47 patients between 2009 and 2019. All patients were treated at the University of Pennsylvania Health System Diffuse Malignant Peritoneal Mesothelioma Malignant mesothelioma is a cancer that affects an estimated 2,500 Americans each year. All forms of mesothelioma have been linked to asbestos exposure. Diffuse malignant peritoneal mesothelioma (DMPM) is a rare form of malignant mesothelioma. Up to 15% of malignant mesothelioma cases are DMPM. DMPM is usually treated with surgery and chemotherapy. This study looked at the role and timing of chemotherapy for patients with … Continue reading Neoadjuvant Chemotherapy Offers Safe Treatment for Mesothelioma
The Link Between Surgery and Radiotherapy for Mesothelioma
A study from the Journal of Clinical Oncology has reviewed the link between radiotherapy and surgery. This is exciting new research in mesothelioma treatment. The study was conducted by mesothelioma experts in Australia. Malignant mesothelioma is a rare and aggressive cancer that rarely responds to a single cancer therapy. Malignant mesothelioma is almost always caused by exposure to asbestos. Usually, that happens in the workplace. Exciting New Research There is ongoing research exploring surgical options for mesothelioma. There are two common surgical procedures for mesothelioma: extrapleural pneumonectomy and pleurectomy decortication. Extrapleural pneumonectomy involves removing the lung affected by mesothelioma. Part of the diaphragm and the linings of the lung and heart are also removed. Pleurectomy decortication is a two-part surgical … Continue reading The Link Between Surgery and Radiotherapy for Mesothelioma
KRAS Gene Shows Promise for Malignant Pleural Mesothelioma Treatments
A new KRAS gene pathway may contribute to future precision medicine treatment for mesothelioma. Malignant pleural mesothelioma is caused by asbestos inhalation. It is a rare, incurable cancer of the mesothelial cells lining the lungs and the chest wall. This form of mesothelioma occurs after asbestos exposure in people with a genetic mutation. The mutation is represented by patients with an inherited cancer syndrome. These patients typically have an even worse prognosis than other mesothelioma patients. A mutation of the KRAS gene may play a role in mesothelioma. A more complex genetic picture may also help explain why some asbestos-exposed workers get the disease and some do not. Discovery of a DNA Gene Mutation Malignant pleural mesothelioma is a rare … Continue reading KRAS Gene Shows Promise for Malignant Pleural Mesothelioma Treatments
New ‘Drug Factory’ Implant Eliminates Mesothelioma in Mice
A new ‘drug factory’ implant has eliminated advanced-stage mesothelioma tumors in mice. The treatment is effective in just a few days. It works by combining a “drug factory” implant with a checkpoint inhibitor drug. The news comes from researchers at Rice University and Baylor College of Medicine. The treatment worked in 100% of the animals treated. And it shows amazing hope for the future of mesothelioma. How the Treatment Works The treatment uses tiny drug-producing beads no larger than the tip of a needle. The beads go to work next to the mesothelioma tumor. Here, they work to produce continuous, high doses of interleukin-2 (IL-2). IL-2 is a natural compound that triggers white blood cells to fight cancer. The study … Continue reading New ‘Drug Factory’ Implant Eliminates Mesothelioma in Mice
The RARECARE Project: An International Network Includes Mesothelioma
The RARECARE Project is a network of international clinicians who support rare tumor patients. This includes malignant mesothelioma, the asbestos-caused cancer. RARECARE wants to ensure access to clinical trials. And to the second opinion of cancer specialists. They are working towards guaranteeing equal health care access and better care management. Humble Beginnings In 2008, the European Commission started the RARECARE project. It is a cancer registry with patient data. They are trying to define the incidence, prevalence, and outcome of rare cancers. Soon, the RARECARE registry led to a second project, RARECAREnet. This updated and enlarged the available information on rare cancers in Europe. Mesothelioma remains one of the rarest of rare cancers. It is more common in the UK … Continue reading The RARECARE Project: An International Network Includes Mesothelioma
Localized Mesothelioma Successfully Treated with Chemotherapy and Surgery
A patient with a rare, localized malignant pleural mesothelioma has been successfully treated. The patient received chemotherapy and surgery and has been disease-free for 12 months. Many believe that a localized form of pleural mesothelioma might have a better survival outlook. This is compared with patients who have the more common, diffuse variety. This latest report comes from a Japanese team of thoracic surgeons. Local vs. Diffuse Mesothelioma Malignant mesothelioma is a rare cancer affecting an estimated 2,500 Americans annually. All forms of mesothelioma have been linked to asbestos exposure. Malignant pleural mesothelioma is the most common form of malignant mesothelioma. Most pleural mesothelioma patients have a type of cancer that tends to spread quickly. It spreds across the thin membrane … Continue reading Localized Mesothelioma Successfully Treated with Chemotherapy and Surgery
Mesothelioma Multidisciplinary Team Improves Patient Outcomes
Oxford University Hospital found that a multidisciplinary team is best in mesothelioma care. This treatment approach includes many doctors who are experts in different specialties. Together, they offer the best clinical decision-making team, and they improve patient outcomes. There are many factors that impact clinical decision-making. But this new report focuses on which factors improve mesothelioma patient care. And which factors support informed decisions about follow-up care. Results showed that the most important factor is a strong team of doctors. Two Heads are Better than One Malignant pleural mesothelioma is a rare, incurable cancer coming from asbestos exposure. Patients have a poor prognosis and a median survival rate of 8 to 14 months. Differences in mesothelioma clinical decision-making are common. … Continue reading Mesothelioma Multidisciplinary Team Improves Patient Outcomes
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