An exciting new use for an old drug is shining a spotlight on the potential for repurposing previously approved drugs to treat malignant mesothelioma faster and more effectively. Malignant mesothelioma is the cancer most closely associated with the mineral asbestos. Although it’s incidence is slowly declining in some parts of the world, mesothelioma continues to rise in many poor countries where asbestos regulation is lax … Continue reading Could Drug “Repurposing” Be the Cure for Mesothelioma?
New evidence suggests that a pulmonary rehabilitation program that comes to them might help patients recover after pleural mesothelioma treatment. Experts in pulmonary cancers at several French institutions recently published what they called a “real-life feasibility study” of home-based rehab in patients who had received chemotherapy for either lung cancer or malignant pleural mesothelioma. Previous research has shown that these patients are typically less physically … Continue reading Home-Based Rehab Helps Mesothelioma Patients Bounce Back After Chemotherapy
A new report suggests that too many mesothelioma patients and their families may not be coping as well as they could be with the implications of their diagnosis. Italian researchers in environmental health, occupational disease, and psychology conducted extensive interviews with 10 mesothelioma patients and 9 of their caregivers. In a report in the journal Frontiers in Psychology, the team concluded that families with malignant … Continue reading Measuring the Emotional Toll of Mesothelioma
A new study is asking the question, is it possible to remove a malignant mesothelioma tumor with pleurectomy-decortication (P/D) without risking the spread of new tumors? P/D, the lung-sparing pleural mesothelioma surgery, has become the preferred approach in many cases where mesothelioma has not spread to the lung tissue. Most studies have found that P/D has a lower complication rate, produces less pain, and allows for faster … Continue reading New Surgical Technique May Improve Mesothelioma Survival
Researchers at one of the nation’s top cancer institutes are betting on a combination of radiation and immunotherapy in the continued pursuit of better treatments for malignant mesothelioma. Memorial Sloan Kettering in New York is now recruiting relapsed mesothelioma patients into a safety and efficacy study of stereotactic body radiation therapy (SBRT) and the immunotherapy drug avelumab. The new trial is based on the idea … Continue reading New Mesothelioma Treatment Combines Immunotherapy and Targeted Radiation
A new Japanese study is calling into question the value of a common prognostic test for people with malignant pleural mesothelioma. The test is called the neutrophil-to-lymphocyte ratio or NLR and it is used in many types of diseases, including mesothelioma, as a marker for inflammation. But in a new report published in the journal In Vivo, researchers with the Hyogo Prefectural Amagasaki General Medical … Continue reading Blood Test May Not Predict Mesothelioma Survival as Well as Hoped
Doctors at Wake Forest University are using miniature lab-grown three dimensional tumors to test personalized mesothelioma treatments. The mini-tumors are known as organoids and are grown from biopsy tissue taken from patients diagnosed with mesothelioma. Researchers say they can serve as models to try out new mesothelioma therapies before using them on patients. “There is a need for model systems to help predict personalized responses … Continue reading Mini-Tumors May Help Doctors Develop Personalized Mesothelioma Treatments
A new stem cell vaccine that has proven effective against malignant mesothelioma and several other cancers in mice might offer a promising new way to treat the asbestos cancer. Although rare, malignant mesothelioma is one of the most treatment-resistant malignancies. Even with aggressive therapies, most people diagnosed with mesothelioma do not survive longer than about 18 months. But research conducted at Stanford University and published in … Continue reading Could Stem Cell Vaccine Lead to Mesothelioma Cure?
New evidence shows there is wide disparity in global rates of malignant mesothelioma, the aggressive disease also known as “asbestos cancer”. The study compared cross sectional mortality rates over a four-year period, as well as trends over almost 20 years (1994 – 2013). The data was compiled by Egyptian oncologist Omar Abdel-Rahman of Ain Shams University in Cairo and reveals almost a 10-fold variation in … Continue reading Study Finds Wide Disparity in Global Mesothelioma Rates
The news this week that a compound found in asparagus and other foods may contribute to the spread of breast cancer has some wondering if patients with other types of cancer – such as malignant pleural mesothelioma – should stop eating asparagus. The study appears in the journal Nature and suggests that asparagine may fuel the mechanism that helps certain kinds of breast cancer cells … Continue reading Should Mesothelioma Patients Give Up Asparagus to Boost Survival?