Telomere Length May Be Key to Earlier Detection of Pleural Mesothelioma

Japanese pathologists have a new theory that may lead to earlier detection and better outcomes for people with malignant pleural mesothelioma. Researchers led by the International University of Health and Welfare in Tokyo say exposure to asbestos appears to shorten the telomeres that protect the ends of DNA strands. The discovery could give doctors another way to diagnose malignant mesothelioma in time to implement more effective treatments. What are Telomeres? Telomeres are the caps on the end of each strand of DNA. According to Telomere Activation Sciences, telomeres function like the plastic tips on the ends of shoelaces. Like those tips, telomeres help protect chromosomes from becoming frayed and damaged. When DNA is damaged, normal cellular processes are disrupted and … Continue reading Telomere Length May Be Key to Earlier Detection of Pleural Mesothelioma »

Opdivo for Malignant Mesothelioma: Could a Lower Dose Work?

There is new evidence that low doses of the drug Opdivo (nivolumab) may extend lung cancer survival as well as the standard dose—at a much lower cost. The news may have implications for people with the lung-related asbestos cancer, malignant mesothelioma, who are also sometimes treated with Opdivo. Pleural mesothelioma is a hard-to-treat cancer that grows on the lining around the lungs and causes many of the same symptoms as lung cancer. Some evidence has suggested that Opdivo, an immunotherapy drug already approved for the treatment of recurrent lung cancer, may soon become the first drug approved for recurrent mesothelioma, too. Now, a newly-published Korean study finds that patients may not need as much of the drug as originally thought … Continue reading Opdivo for Malignant Mesothelioma: Could a Lower Dose Work? »

Hundreds of Mesothelioma Deaths Predicted for Taiwan

Taiwanese cancer researchers say a total asbestos ban is “urgently needed” to help stem the tide of pleural mesothelioma cases predicted in the next 30 years. While the incidence of malignant mesothelioma has finally begun to level off in some countries, its incidence worldwide continues to grow. Taiwan is just one example of a country where mesothelioma rates, as well as the rates of other asbestos-related diseases (ARDs), are expected to keep climbing for at least another couple of years. Even after 2020, the authors of a new mesothelioma study say the disease will continue to be a problem for decades, highlighting the need for Taiwan to implement a total asbestos ban and devote more resources to mesothelioma screening, diagnosis, … Continue reading Hundreds of Mesothelioma Deaths Predicted for Taiwan »

Unravelling the Mystery Behind Mesothelioma Tumors

In what could be a step closer to a mesothelioma cure, French cancer researchers say they have identified two of the key genetic pathways responsible for triggering mesothelioma in asbestos-exposed people. Led by Inserm (The French National Institute of Health and Medical Research), the study focused on mice that had been genetically engineered with mutations on certain tumor-suppressor genes known to play a role in malignant mesothelioma in people. Learning About Human Mesothelioma from Mice In the experiment, published in the International Journal of Molecular Sciences, some of the genetically engineered mice, as well as some normal (wild type) mice, were exposed to asbestos while others were not. The goal was to understand exactly what is happening at the molecular … Continue reading Unravelling the Mystery Behind Mesothelioma Tumors »

Nurse Compassion May Improve Mesothelioma Outcomes

counseling

Recent research suggests that how people with lung cancers like pleural mesothelioma are treated by their oncology nurses can have a direct bearing on their treatment outcomes. The news is based on a groundbreaking study conducted at two Chinese universities and published in Psychology Research and Behavior Management. Empathy and Lung Cancer Survival The study focused on 365 lung cancer patients who were cared for by 30 different nurses at a Beijing hospital between October 2016 and May 2017. Researchers used a test called flow cytometry to measure the activity of cancer fighting immune system cells including T-cells, B-cells and natural killer (NK) cells. These cells are also activated in patients battling malignant mesothelioma and other cancers. This “cellular immunity” … Continue reading Nurse Compassion May Improve Mesothelioma Outcomes »

Pleural Mesothelioma Patients Feel Better with This Symptom Management Regimen

For mesothelioma patients with indwelling pleural catheters, new research suggests that draining them daily can improve their quality of life and may even resolve the problem faster than waiting until symptoms arise. Pleural effusions, a buildup of fluid between the layers of the pleural membrane surrounding the lungs, is a fact of life for patients with several types of cancer, including pleural mesothelioma. If not addressed, this fluid accumulation often leads to life-limiting side effects like chest pain, coughing, and breathlessness.   Managing Pleural Effusions from Malignant Mesothelioma There are surgical procedures aimed at preventing pleural effusions in mesothelioma patients and resolving symptoms by physically closing the spaces where fluid accumulates. Closing up the pleural space is known as pleurodesis. … Continue reading Pleural Mesothelioma Patients Feel Better with This Symptom Management Regimen »

Lung Fluid Tests May Lead to Earlier Mesothelioma Diagnosis

Using the free-floating cancer cells present in lung-fluid to diagnose malignant mesothelioma may lead to earlier detection and better outcomes. That is the conclusion of cancer researchers at Stockholm’s Karolinska University Hospital. The team’s goal was to evaluate the established criteria for cytopathological diagnosis of mesothelioma, i.e. diagnosis using cells found in fluid (effusions) instead of cells from a tissue biopsy. In a newly published article in the Archives of Pathological and Laboratory Medicine, the researchers observe, “Despite the difficulties in recognizing malignant cells present in those early effusions, they are often the first available biologic material for diagnosis.” Diagnosing Pleural  Mesothelioma Malignant pleural mesothelioma, a rare but fast-growing cancer associated with asbestos exposure, is notoriously difficult to diagnose. Diagnosis … Continue reading Lung Fluid Tests May Lead to Earlier Mesothelioma Diagnosis »

Drug-Coated Film May Prevent Mesothelioma Recurrence

Mesothelioma researchers in Italy have developed a new surgical technique with the potential to dramatically increase the odds of surviving malignant pleural mesothelioma. Pleural mesothelioma is a rare and aggressive cancer that grows on the membranous tissue (pleura) surrounding the lungs. It is most common in people who have ever lived or worked in the presence of deadly asbestos dust.                       The new technique involves placing a drug-coated polymer film directly on the mesothelial surface after tumor-removal surgery as a way to prevent recurrent pleural mesothelioma. In a new article in the European Journal of Pharmaceutical Science, researchers at the University of Parma say the film “almost completely prevented tumor recurrence” in treated mice. Battling Recurrent Mesothelioma The typical treatment … Continue reading Drug-Coated Film May Prevent Mesothelioma Recurrence »

Study Confirms Feasibility and Safety of Minimally Invasive Mesothelioma Surgery

New research suggests that the future of surgery for peritoneal mesothelioma could be much less invasive than it is now—at least for select patients. The study focused on patients with tumors that had spread to the peritoneal membrane that lines the abdomen. This is the place where malignant mesothelioma starts. In a report published in the journal Surgical Endoscopy, an international team of experts concludes that minimally invasive surgery for peritoneal cancers like malignant mesothelioma is both feasible and safe and should be considered for certain patients. CRS/HIPEC Standard of Care for Malignant Mesothelioma Currently, the standard of care for peritoneal mesothelioma is cytoreductive surgery to remove as much of the tumor as possible followed by a rinse of heated … Continue reading Study Confirms Feasibility and Safety of Minimally Invasive Mesothelioma Surgery »

Asbestos Ban Not Enough to Wipe Out Mesothelioma in Italy

Twenty-six years after Italy instituted a ban on cancer-causing asbestos, the number of people dying of malignant mesothelioma is still rising. Researchers with the Istituto Superiore di Sanità in Rome computed the mortality rates from mesothelioma between 2003 and 2014 in each of the country’s 8,047 municipalities and found that more than 16,000 people had died from malignant mesothelioma. Most of those deaths were from pleural mesothelioma and most occurred in areas near industrial asbestos sources. Malignant Mesothelioma and Asbestos Bans An estimated 80 percent of people diagnosed with mesothelioma have some type of known exposure to asbestos, a naturally-occurring fibrous mineral that embeds itself in body tissues. Even though scientists were exploring the connection between asbestos exposure and diseases … Continue reading Asbestos Ban Not Enough to Wipe Out Mesothelioma in Italy »

Get your free copy of
“Surviving Mesothelioma” Today!