Diagnosing Pleural Mesothelioma with Lung Fluid: The Battle of the Biomarkers

Biologist Holding Flasks

A biomarker called soluble mesothelin related peptide (SMRP) may be a more reliable way to diagnose malignant pleural mesothelioma from lung fluid than the protein fibulin-3. That is the finding of Italian researchers who tested the diagnostic performance of the two markers in 120 patients, including 33 mesothelioma patients, in an effort to resolve what they call “conflicting data” on the two methods. SMRP and … Continue reading Diagnosing Pleural Mesothelioma with Lung Fluid: The Battle of the Biomarkers »

Mesothelioma Tumor Thickness May Help Predict Treatment Outcomes

New research out of Canada suggests that mesothelioma tumor thickness could be used to help predict mesothelioma survival and select the best treatments.  Doctors at the University of Toronto compared the thickness of pleural mesothelioma tumors in 65 patients who had not yet received any treatment with their eventual outcomes and found a definite correlation. Summarizing their research in The European Respiratory Journal, the team … Continue reading Mesothelioma Tumor Thickness May Help Predict Treatment Outcomes »

Mesothelioma Patients May Need Special Help After Surgery

Pleural mesothelioma patients who undergo pleurectomy/decortication (P/D) surgery may need customized rehabilitation strategies to help restore their quality of life. That is the finding of a Japanese study conducted by rehabilitation experts at the Hyogo College of Medicine. In a study of malignant pleural mesothelioma patients, the team found that, after P/D, many measures of physical strength and vitality decreased, along with their health-related quality … Continue reading Mesothelioma Patients May Need Special Help After Surgery »

The Impact of Nutritional Status on Mesothelioma Survival

There is new evidence that a mesothelioma patient’s nutritional status could have an impact on their treatment outcomes. A group of Japanese surgeons, oncologists and pathologists compared the treatment responses of 83 patients with pleural mesothelioma and found that patients with the poorest nutritional status tended to have the poorest mesothelioma prognosis. Controlling Nutritional Status Score To reach their conclusion, the researchers used a tool … Continue reading The Impact of Nutritional Status on Mesothelioma Survival »

Radical Mesothelioma Surgery Deemed Not “Clinically Effective”

The heads of a European working group charged with advising cardio-thoracic surgeons on the best ways to treat malignant pleural mesothelioma say the most radical and risky type of surgery is not clinically effective. Dr. Giuseppe Cardillo of Carlo Forlanini Hospital in Rome and Dr. Tom Treasure with University College London (author of the MARS mesothelioma surgery study) detail their conclusion in a Letter to … Continue reading Radical Mesothelioma Surgery Deemed Not “Clinically Effective” »

Mesothelioma Risk in Older School Buildings

A new government report has some sobering news for teachers and students in England: Nearly 20 percent of schools may be failing to adequately protect them from asbestos, the primary cause of malignant pleural mesothelioma. The asbestos management report, issued by the Education Funding Agency, is based on data collected online from more than 5,500 schools in 2016. It offers a disturbing view of mesothelioma risk … Continue reading Mesothelioma Risk in Older School Buildings »

Immunotherapy for Pleural Mesothelioma: Does it Work?

Immunotherapy is an important emerging therapeutic strategy for several types of cancer, but the jury is still out on whether it will eventually be a viable approach for malignant pleural mesothelioma. In a newly-published special report on the immune checkpoint inhibitor tremelimumab, researchers at the University of Salford in the UK call the use of such drugs “largely questionable” for pleural mesothelioma treatment. Their concerns, … Continue reading Immunotherapy for Pleural Mesothelioma: Does it Work? »

Novel Technique Controls Pleural Effusion in Mesothelioma Patients

Japanese researchers have come up with a new method of controlling one of the most bothersome and life-limiting symptoms of late stage malignant mesothelioma – a buildup of fluid around the lungs called malignant pleural effusion. When fluid collects in the space between the layers of the pleural membrane around the lungs, it becomes more difficult for the lungs to expand properly. At this stage, … Continue reading Novel Technique Controls Pleural Effusion in Mesothelioma Patients »

Spice Compound Extends Mesothelioma Survival in Mice

The compound that gives the spice turmeric its yellow color and pungent flavor is once again attracting the attention of mesothelioma researchers. Curcumin has been the subject of numerous mesothelioma studies. The latest one, conducted by scientists at the Department of Experimental Medicine at the University of Rome, finds that the compound has the power to not only kill mesothelioma cells in the lab, but … Continue reading Spice Compound Extends Mesothelioma Survival in Mice »

Scoring Tool Helps Doctors Select Mesothelioma Patients for Clinical Trials

Researchers in London have developed a new way of categorizing patients with advanced malignant mesothelioma that allows them to predict who will benefit the most from participation in a Phase I clinical trial. The Drug Development Unit at the Royal Marsden Hospital already uses a prognostic scoring system for cancer patients to determine which patients would be good candidates for Phase 1 clinical trials of … Continue reading Scoring Tool Helps Doctors Select Mesothelioma Patients for Clinical Trials »