New Biomarker for Early Mesothelioma Diagnosis
Early treatment for mesothelioma is critical for overall survival. Researchers from Italy may have found a biomarker that can identify malignant pleural mesothelioma up to five years before a clinical diagnosis. This is an important area of research for mesothelioma because it is hard for doctors to diagnose this disease until it has become too difficult to treat. The sooner that doctors can diagnose a patient with mesothelioma, the sooner they can begin life-saving treatment. In addition, the current diagnosis methods involve surgically removing cancerous tissue for testing. This type of procedure can be hard even for healthy patients. Because of this, patients who are already too sick from mesothelioma might not be able to get a proper diagnosis. MicroRNA … Continue reading New Biomarker for Early Mesothelioma Diagnosis
New Set of Biomarkers for Mesothelioma
A new set of biomarkers to diagnose mesothelioma has been identified by researchers in Italy. Mesothelioma is a rare type of cancer that is caused by exposure to asbestos. It takes decades for symptoms to appear after being around asbestos. It is also a deadly cancer with an average survival time of 13 months. Diagnosing mesothelioma as early as possible is critical to successful treatment. Doctors diagnose mesothelioma with a few different procedures. They might perform a scan on a patient first. This is usually an x-ray or a CT scan. Once they find a potential cancer site, the doctor needs to remove part of the tissue to take a closer look. The doctor will perform a biopsy to get … Continue reading New Set of Biomarkers for Mesothelioma
KRAS Gene Shows Promise for Malignant Pleural Mesothelioma Treatments
A new KRAS gene pathway may contribute to future precision medicine treatment for mesothelioma. Malignant pleural mesothelioma is caused by asbestos inhalation. It is a rare, incurable cancer of the mesothelial cells lining the lungs and the chest wall. This form of mesothelioma occurs after asbestos exposure in people with a genetic mutation. The mutation is represented by patients with an inherited cancer syndrome. These patients typically have an even worse prognosis than other mesothelioma patients. A mutation of the KRAS gene may play a role in mesothelioma. A more complex genetic picture may also help explain why some asbestos-exposed workers get the disease and some do not. Discovery of a DNA Gene Mutation Malignant pleural mesothelioma is a rare … Continue reading KRAS Gene Shows Promise for Malignant Pleural Mesothelioma Treatments
Mesothelioma and the Promising New Hippo Biomarker
A new review in Targeted Oncology looks at a promising new Hippo biomarker in malignant pleural mesothelioma. The new biomarker is rooted in the mesothelioma molecular pathway. A molecular pathway is how molecules work together inside your body. These pathways control cell function. And they are important in developing mesothelioma treatments. Think of molecular pathways as the airport tower controller. These pathways tell mesothelioma treatments where to go and what to do in the body. If doctors can understand how pathways work, they can develop better treatments. The goal is to develop more, and more effective, mesothelioma treatments. Promising Hippo Pathway in Malignant Pleural Mesothelioma While several drugs have been approved for treating mesothelioma, there aren’t a lot. This is … Continue reading Mesothelioma and the Promising New Hippo Biomarker
Serum IgG4: A New Biomarker for Mesothelioma Pleural Effusion
Egyptian scientists say a new biomarker is very good at identifying mesothelioma. Pleural effusions are pockets of excess fluid. They collect around the lungs of people with certain kinds of cancer and other conditions. Biomarkers in pleural effusions are proteins and other substances found in mesothelioma patients. The new study suggests that using this biomarker the right way can lead to more accurate diagnoses. The Importance of Biomarkers in Pleural Effusions Pleural mesothelioma is a rare cancer of the lung lining. It is a challenge to diagnose. The early symptoms can be as vague as cough and fatigue. But an accurate diagnosis is often the difference between life and death. As tumors grow, mesothelioma patients produce pleural effusions or ‘water … Continue reading Serum IgG4: A New Biomarker for Mesothelioma Pleural Effusion
Identifying New MicroRNA Tumor Biomarkers for Mesothelioma
Identifying New MicroRNA Tumor Biomarkers for Mesothelioma Italian researchers have taken an important step forwards in what amounts to a microRNA tumor biomarker for mesothelioma. Exposure to asbestos fibers causes malignant pleural mesothelioma. An early diagnosis and comprehensive health monitoring is vital for patients exposed to asbestos fibers. Researchers at the University of Catania in Italy say these two clinical issues “may be solved by the identification of specific biomarkers.” A new article in Nature Scientific Reports identifies RNA molecules could serve as a microRNA signature for mesothelioma. This “signature” could help doctors distinguish mesothelioma from other types of cancer. The Challenge of Mesothelioma Diagnosis Pleural mesothelioma is particularly hard to diagnose. The early symptoms of mesothelioma are similar to the … Continue reading Identifying New MicroRNA Tumor Biomarkers for Mesothelioma
Genomic Experts Report Most Complete Picture of Mesothelioma to Date
Australian and American genomic experts have completed a key step in improving the treatment of pleural mesothelioma. A new study gives results from a large study of malignant pleural mesothelioma Pleural mesothelioma is a type of cancer that develops on the thin layer of tissue that covers the lungs and chest wall. Asbestos causes mesothelioma and other asbestos-related diseases. Asbestos was used in thousands of industrial, commercial, construction, automotive, and consumer products. Pleural mesothelioma occurs in about 2,000 people in the United States every year. Scientists at the National Centre for Asbestos-Related Disease have taken a dramatic leap forward in the understanding of pleural mesothelioma. DNA Genes Impact Personalized Treatment Plans Previous genomic studies of malignant pleural mesothelioma were limited. … Continue reading Genomic Experts Report Most Complete Picture of Mesothelioma to Date
New Tips for Diagnosing Malignant Peritoneal Mesothelioma
Malignant peritoneal mesothelioma is an aggressive cancer that often mimics other conditions. This can make it difficult to get a definitive diagnosis. But a new report in Pathology Case Reviews provides tips for identifying peritoneal mesothelioma. Diagnosing Malignant Peritoneal Mesothelioma Mesothelioma is usually diagnosed after a person experiencing symptoms goes to a doctor. Patients often complain of vague abdominal symptoms, such as pain, nausea, bloating, weight loss. Distinguishing peritoneal mesothelioma from other cancers is important to ensure appropriate treatment. One thing a doctor may do is perform a tissue biopsy. The doctor will remove a part of the tissue (suspected mesothelioma) for examination. A biopsy is the “gold standard” and the single most important procedure for an accurate diagnosis. Doctors … Continue reading New Tips for Diagnosing Malignant Peritoneal Mesothelioma
New Advancements in Personalized Medicine for Mesothelioma
Genomics is a new branch of medicine that involves using a patient’s genetic information to create personalized treatment. New research has begun looking at genetic personalized medicine for mesothelioma. Students from the University of Montana are developing personalized medicine for mesothelioma. Personalized Medicine and Mesothelioma Treatment Mesothelioma is a rare rare and aggressive cancer often caused by asbestos exposure. Environmental exposure to asbestos often causes a higher incidence of malignant mesothelioma. There are approximately 2,000 cases of mesothelioma diagnosed in the U.S. every year. Current standard of care involves a multi-targeted drug combination of Pemetrexid and Cisplatin. This is the only FDA approved chemotherapy for mesothelioma. Chemotherapy is a group of toxic drugs that kill mesothelioma cells by damaging their … Continue reading New Advancements in Personalized Medicine for Mesothelioma
New Anti-Mesothelioma Antibody and Biomarker Discovered
Dr. Tsuji is working on discovering specific cancer antigens for malignant mesothelioma. A new study from the Gunma University of Health and Welfare shows a new anti-mesothelioma antibody for the diagnosis and treatment of mesothelioma. The use of antibody drugs is becoming more popular in the treatment of mesothelioma. Antibody drugs are immunotherapy treatments. They recruit your body’s germ-fighting immune system to fight against mesothelioma. One the of biggest problems with mesothelioma immunotherapy is a lack of biomarkers. Mesothelioma is Difficult to Diagnose and Treat with Biomarkers Mesothelioma is a rare and aggressive cancer often caused by asbestos exposure. Malignant mesothelioma is characterized by poor prognosis and short survival. Malignant mesothelioma is considered a treatment-resistant (intractable) cancer. Clinicians and researchers … Continue reading New Anti-Mesothelioma Antibody and Biomarker Discovered
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