Tri-Modality Treatment Extends Mesothelioma Survival

radiologist

New research suggests that a combination of lung-sparing surgery, highly targeted radiotherapy, and chemotherapy may bolster survival in people with malignant pleural mesothelioma. Researchers at Memorial Sloan Kettering Cancer Center in New York have just published some promising findings on trimodality mesothelioma treatment with hemithoracic intensity-modulated pleural radiotherapy (IMPRINT). Conventional RT vs IMPRINT The team analyzed the cases of 209 mesothelioma patients who underwent the … Continue reading Tri-Modality Treatment Extends Mesothelioma Survival »

Platelet Count Linked to Peritoneal Mesothelioma Survival After Surgery

Peritoneal mesothelioma patients whose bodies produce too many blood platelets may not be good candidates for the treatment combination known as CRS with HIPEC. Cytoreductive surgery (CRS) followed by hyperthermic intraperitoneal chemotherapy (HIPEC) is a process for removing as much peritoneal mesothelioma from the abdomen as possible and killing any cancer cells left behind with a wash of heated medication. It has become the preferred … Continue reading Platelet Count Linked to Peritoneal Mesothelioma Survival After Surgery »

Diagnosing Pleural Mesothelioma with Lung Fluid: The Battle of the Biomarkers

Biologist Holding Flasks

A biomarker called soluble mesothelin related peptide (SMRP) may be a more reliable way to diagnose malignant pleural mesothelioma from lung fluid than the protein fibulin-3. That is the finding of Italian researchers who tested the diagnostic performance of the two markers in 120 patients, including 33 mesothelioma patients, in an effort to resolve what they call “conflicting data” on the two methods. SMRP and … Continue reading Diagnosing Pleural Mesothelioma with Lung Fluid: The Battle of the Biomarkers »

Mesothelioma Tumor Thickness May Help Predict Treatment Outcomes

New research out of Canada suggests that mesothelioma tumor thickness could be used to help predict mesothelioma survival and select the best treatments.  Doctors at the University of Toronto compared the thickness of pleural mesothelioma tumors in 65 patients who had not yet received any treatment with their eventual outcomes and found a definite correlation. Summarizing their research in The European Respiratory Journal, the team … Continue reading Mesothelioma Tumor Thickness May Help Predict Treatment Outcomes »

Mesothelioma Patients May Need Special Help After Surgery

Pleural mesothelioma patients who undergo pleurectomy/decortication (P/D) surgery may need customized rehabilitation strategies to help restore their quality of life. That is the finding of a Japanese study conducted by rehabilitation experts at the Hyogo College of Medicine. In a study of malignant pleural mesothelioma patients, the team found that, after P/D, many measures of physical strength and vitality decreased, along with their health-related quality … Continue reading Mesothelioma Patients May Need Special Help After Surgery »

Radical Mesothelioma Surgery Deemed Not “Clinically Effective”

The heads of a European working group charged with advising cardio-thoracic surgeons on the best ways to treat malignant pleural mesothelioma say the most radical and risky type of surgery is not clinically effective. Dr. Giuseppe Cardillo of Carlo Forlanini Hospital in Rome and Dr. Tom Treasure with University College London (author of the MARS mesothelioma surgery study) detail their conclusion in a Letter to … Continue reading Radical Mesothelioma Surgery Deemed Not “Clinically Effective” »

Maintenance Work Can Carry a High Mesothelioma Risk

A CDC report out this week on the incidence of malignant mesothelioma in the US suggests that people who renovate or do repairs and maintenance work on older asbestos-containing buildings may have the highest risk for mesothelioma in the coming years. The report, entitled “Malignant Mesothelioma Mortality – United States, 1999 – 2015” shows that mesothelioma diagnoses are still on the rise, despite regulations put … Continue reading Maintenance Work Can Carry a High Mesothelioma Risk »

Novel Technique Controls Pleural Effusion in Mesothelioma Patients

Japanese researchers have come up with a new method of controlling one of the most bothersome and life-limiting symptoms of late stage malignant mesothelioma – a buildup of fluid around the lungs called malignant pleural effusion. When fluid collects in the space between the layers of the pleural membrane around the lungs, it becomes more difficult for the lungs to expand properly. At this stage, … Continue reading Novel Technique Controls Pleural Effusion in Mesothelioma Patients »

Scoring Tool Helps Doctors Select Mesothelioma Patients for Clinical Trials

Researchers in London have developed a new way of categorizing patients with advanced malignant mesothelioma that allows them to predict who will benefit the most from participation in a Phase I clinical trial. The Drug Development Unit at the Royal Marsden Hospital already uses a prognostic scoring system for cancer patients to determine which patients would be good candidates for Phase 1 clinical trials of … Continue reading Scoring Tool Helps Doctors Select Mesothelioma Patients for Clinical Trials »

Mesothelioma Diagnosis: Fluid Cytology Versus Biopsy

A mesothelioma diagnosis using pleural fluid is just as reliable at predicting survival as a diagnosis based on a tissue sample. That conclusion, published in a recent issue of the British Journal of Cancer, is based on an analysis of more than 2,000 cases of malignant mesothelioma over 42 years. Researchers from the University of Western Australia and Curtin University in Perth compared the survival … Continue reading Mesothelioma Diagnosis: Fluid Cytology Versus Biopsy »