New Drugs | Surviving Mesothelioma

Boosting Mesothelioma Survival with VEGF-Inhibitor

The VEGF inhibitor cediranib may not yet be out of the running as a mesothelioma treatment. Although previous studies have found it to have dose-limiting side effects, a new study in the Journal of Thoracic Oncology finds that, at the right dose, it could boost the effectiveness of standard mesothelioma chemotherapy. What is Cediranib? Cediranib, an oral drug made by Astra Zeneca, is a powerful … Continue reading Boosting Mesothelioma Survival with VEGF-Inhibitor »

Cholesterol Drug May Protect Mesothelioma Patients from Radiation

A new study suggests that the cholesterol-lowering drug pravastatin could one-day be used to help protect mesothelioma patients from the damaging side effects of radiotherapy. According to Japanese researchers, mice with malignant mesothelioma who were given pravastatin (Pravachol) in drinking water prior to receiving radiation experienced less damage to healthy cells in their lungs and intestines. The results suggest that pravastatin might make radiotherapy safer … Continue reading Cholesterol Drug May Protect Mesothelioma Patients from Radiation »

Searching for New Mesothelioma Drugs Among African Plants

Doctors in Cameroon and Turkey say two types of African plants deserve more study as potential treatments for malignant mesothelioma and other intractable cancers. The plants, including Elephantopus mollis,, Kalanchoe crenata, and four other medicinal plants, contain compounds that triggered cell death when tested on mesothelioma cells in the laboratory. At present, there is no cure for mesothelioma and no drugs that consistently slow its … Continue reading Searching for New Mesothelioma Drugs Among African Plants »

VEGF-Inhibitor Looks Promising for Malignant Mesothelioma

There is more encouraging news about the monoclonal antibody bevacizumab (Avastin) and its potential to boost the effectiveness of chemotherapy for people with malignant pleural mesothelioma. A pair of oncology researchers from Texas have just released their summary of the the most recent published studies on bevacizumab. They conclude that, for the right patients, bevacizumab may improve mesothelioma outcomes and extend survival by blocking tumor blood … Continue reading VEGF-Inhibitor Looks Promising for Malignant Mesothelioma »

New Prospects for Treating Malignant Mesothelioma with Curcumin

There is more evidence that the active ingredient in turmeric may have the power to help combat malignant mesothelioma. A new French study on curcumin finds that the compound not only slowed the growth of one of the rarest types of mesothelioma tumor cells in the laboratory but also reduced total tumor mass in lab rats in just two weeks. Evaluating Curcumin’s Effect on Mesothelioma … Continue reading New Prospects for Treating Malignant Mesothelioma with Curcumin »

New Combination Treatment for Rare Mesothelioma Subtypes

woman mesothelioma doctor holds syringe

An enzyme shown to help fight melanoma and liver cancer may offer new hope to patients with some of the most treatment-resistant mesothelioma tumors. Malignant mesothelioma is a rare, asbestos-linked cancer of internal membranes. Although all forms are highly resistant to standard cancer therapies, the sarcomatoid and biphasic subtypes – which are the rarest forms of mesothelioma – typically carry the worst prognosis. But a … Continue reading New Combination Treatment for Rare Mesothelioma Subtypes »

MS Drug May Help Treat Malignant Mesothelioma, Too

Preliminary tests of a potential new mesothelioma treatment have yielded some exciting results at the University of Hawaii Cancer Center. Mesothelioma researchers there are evaluating an immune system modulator called FTY720 or fingolimod. Derived from a fungus called Iscaria sinclairii, FTY720 has been used to treat the relapsing form of multiple sclerosis. Although FTY720 has shown what the research team calls “therapeutic potential” in some … Continue reading MS Drug May Help Treat Malignant Mesothelioma, Too »

Spice Compound Extends Mesothelioma Survival in Mice

The compound that gives the spice turmeric its yellow color and pungent flavor is once again attracting the attention of mesothelioma researchers. Curcumin has been the subject of numerous mesothelioma studies. The latest one, conducted by scientists at the Department of Experimental Medicine at the University of Rome, finds that the compound has the power to not only kill mesothelioma cells in the lab, but … Continue reading Spice Compound Extends Mesothelioma Survival in Mice »

Scoring Tool Helps Doctors Select Mesothelioma Patients for Clinical Trials

Researchers in London have developed a new way of categorizing patients with advanced malignant mesothelioma that allows them to predict who will benefit the most from participation in a Phase I clinical trial. The Drug Development Unit at the Royal Marsden Hospital already uses a prognostic scoring system for cancer patients to determine which patients would be good candidates for Phase 1 clinical trials of … Continue reading Scoring Tool Helps Doctors Select Mesothelioma Patients for Clinical Trials »

Compound in Pacific Sea Squirt Kills Mesothelioma Cells

There is new evidence that compounds isolated from a sea squirt found in the waters off of the Indonesian coast may hold the key to fighting mesothelioma and several other malignancies. The potential anticancer and antimicrobial properties are found in polysulfur aromatic alkaloids found in a Pacific sea squirt whose scientific name is Lissoclinum badium. In a new article in the Journal of Natural Products, … Continue reading Compound in Pacific Sea Squirt Kills Mesothelioma Cells »

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