Mesothelioma Patients Recruited to Test Promising New Combo Drug

Patients with malignant mesothelioma who have not gotten better after chemotherapy are being invited to enroll in a clinical trial of a combination drug that could be the future of mesothelioma treatment. The drug is called SEL-403. Developed by Selecta Biosciences, the drug seeks to get around the problem of the body producing antibodies that decrease the effectiveness of certain mesothelioma drugs. What is SLE-403 … Continue reading Mesothelioma Patients Recruited to Test Promising New Combo Drug »

Could Drug “Repurposing” Be the Cure for Mesothelioma?

An exciting new use for an old drug is shining a spotlight on the potential for repurposing previously approved drugs to treat malignant mesothelioma faster and more effectively. Malignant mesothelioma is the cancer most closely associated with the mineral asbestos. Although it’s incidence is slowly declining in some parts of the world, mesothelioma continues to rise in many poor countries where asbestos regulation is lax … Continue reading Could Drug “Repurposing” Be the Cure for Mesothelioma? »

Experimental Mesothelioma Treatment Produces “Strong Antitumor Activity”

Italian scientists have released some potentially exciting news detailing their experiments with a new kind of treatment for malignant mesothelioma. The combination treatment uses elements of traditional Chinese medicine as well as a natural compound isolated from a marine sponge. Led by chemists from the University of Milan, the experiments involved giving the combination to mice carrying human mesothelioma tumors. While standard chemotherapy has only … Continue reading Experimental Mesothelioma Treatment Produces “Strong Antitumor Activity” »

Mesothelioma Treatment May Be More Effective Without This Enzyme

An international team of researchers has published data they believe could dramatically boost the effectiveness of chemotherapy for malignant mesothelioma. Malignant mesothelioma is a highly lethal, asbestos-linked cancer. One of the reasons it is so difficult to cure is that it is resistant to all of the standard cancer drugs. Now, scientists with the University of New Mexico, the University of Kansas, and Semmelweis University … Continue reading Mesothelioma Treatment May Be More Effective Without This Enzyme »

Long-Term Mesothelioma Survival with Mistletoe Extract

Mesothelioma researchers are calling for more study of compounds extracted from European mistletoe after a German pleural mesothelioma patient survived for more than four years with no other treatment. Pleural mesothelioma is an aggressive cancer caused by exposure to asbestos. Although many different types of new mesothelioma treatments are under investigation, there is no cure. An Alternative Mesothelioma Treatment? Most mesothelioma patients receive some combination … Continue reading Long-Term Mesothelioma Survival with Mistletoe Extract »

Bullfrog Eggs May Hold the Secret to Mesothelioma Survival

Researchers in Japan believe they may have discovered a new and more effective drug for the intractable asbestos cancer, malignant pleural mesothelioma – and it comes from an unlikely source. Sialic acid-binding lectin (cSBL) is a protein derived from the eggs of bullfrogs. It has the ability to bind to cell membranes and appears to exhibit antitumor activity through the degradation of RNA. Previous studies have … Continue reading Bullfrog Eggs May Hold the Secret to Mesothelioma Survival »

Blocking This Cellular Process Could Help Mesothelioma Chemotherapy Work Better

Researchers in California and Boston say blocking a process by which cells break down and recycle their components into new cells could make mesothelioma tumors more susceptible to chemotherapy. Although the process, known as autophagy, is a natural part of the lives of cells, it can also be induced by certain drugs. Emerging research suggests that the multi-stage process is not only more complex than … Continue reading Blocking This Cellular Process Could Help Mesothelioma Chemotherapy Work Better »

Three-Drug Combo is New Standard of Care for Pleural Mesothelioma in France

France has a new standard of care for people with unresectable malignant pleural mesothelioma. Along with the chemotherapy drugs cisplatin and pemetrexed (Alimta), French doctors are now regularly also using bevacizumab (Avastin) to boost the effectiveness of mesothelioma chemotherapy. The addition of Avastin to standard mesothelioma care came after the 2016 French-led mesothelioma avastin cisplatin pemetrexed study (MAPS) showed that the VEGF inhibitor improved mesothelioma … Continue reading Three-Drug Combo is New Standard of Care for Pleural Mesothelioma in France »

FGFR Inhibitors May Offer New Way to Treat Malignant Pleural Mesothelioma

Drugs that inhibit a particular cell signaling pathway might offer a new way to help treat the intractable asbestos cancer, malignant mesothelioma. Fibroblast growth factor receptor (FGFR) is a tyrosine kinase signaling pathway that plays a fundamental role in the development of embryos, tissue regeneration, and the growth of new blood vessels (angiogenesis). Recent evidence suggests that it may also impact the development of cancers … Continue reading FGFR Inhibitors May Offer New Way to Treat Malignant Pleural Mesothelioma »

New Biomarker Could Help Eradicate Mesothelioma Resistance to Chemotherapy

Researchers in the Netherlands have unveiled what may be a major breakthrough in the chemotherapeutic treatment of malignant mesothelioma. Malignant mesothelioma, a rare and virulent cancer caused by asbestos exposure, is notoriously resistant to standard cancer treatments, including chemotherapy. Even the only chemotherapy drug specifically approved for the treatment of mesothelioma, Alimta (pemetrexed), only works for some patients. Now, a new study published in the … Continue reading New Biomarker Could Help Eradicate Mesothelioma Resistance to Chemotherapy »

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