New Drugs | Surviving Mesothelioma

VEGF-Inhibitor Looks Promising for Malignant Mesothelioma

There is more encouraging news about the monoclonal antibody bevacizumab (Avastin) and its potential to boost the effectiveness of chemotherapy for people with malignant pleural mesothelioma. A pair of oncology researchers from Texas have just released their summary of the the most recent published studies on bevacizumab. They conclude that, for the right patients, bevacizumab may improve mesothelioma outcomes and extend survival by blocking tumor blood … Continue reading VEGF-Inhibitor Looks Promising for Malignant Mesothelioma »

New Prospects for Treating Malignant Mesothelioma with Curcumin

There is more evidence that the active ingredient in turmeric may have the power to help combat malignant mesothelioma. A new French study on curcumin finds that the compound not only slowed the growth of one of the rarest types of mesothelioma tumor cells in the laboratory but also reduced total tumor mass in lab rats in just two weeks. Evaluating Curcumin’s Effect on Mesothelioma … Continue reading New Prospects for Treating Malignant Mesothelioma with Curcumin »

New Combination Treatment for Rare Mesothelioma Subtypes

woman mesothelioma doctor holds syringe

An enzyme shown to help fight melanoma and liver cancer may offer new hope to patients with some of the most treatment-resistant mesothelioma tumors. Malignant mesothelioma is a rare, asbestos-linked cancer of internal membranes. Although all forms are highly resistant to standard cancer therapies, the sarcomatoid and biphasic subtypes – which are the rarest forms of mesothelioma – typically carry the worst prognosis. But a … Continue reading New Combination Treatment for Rare Mesothelioma Subtypes »

MS Drug May Help Treat Malignant Mesothelioma, Too

Preliminary tests of a potential new mesothelioma treatment have yielded some exciting results at the University of Hawaii Cancer Center. Mesothelioma researchers there are evaluating an immune system modulator called FTY720 or fingolimod. Derived from a fungus called Iscaria sinclairii, FTY720 has been used to treat the relapsing form of multiple sclerosis. Although FTY720 has shown what the research team calls “therapeutic potential” in some … Continue reading MS Drug May Help Treat Malignant Mesothelioma, Too »

Spice Compound Extends Mesothelioma Survival in Mice

The compound that gives the spice turmeric its yellow color and pungent flavor is once again attracting the attention of mesothelioma researchers. Curcumin has been the subject of numerous mesothelioma studies. The latest one, conducted by scientists at the Department of Experimental Medicine at the University of Rome, finds that the compound has the power to not only kill mesothelioma cells in the lab, but … Continue reading Spice Compound Extends Mesothelioma Survival in Mice »

Scoring Tool Helps Doctors Select Mesothelioma Patients for Clinical Trials

Researchers in London have developed a new way of categorizing patients with advanced malignant mesothelioma that allows them to predict who will benefit the most from participation in a Phase I clinical trial. The Drug Development Unit at the Royal Marsden Hospital already uses a prognostic scoring system for cancer patients to determine which patients would be good candidates for Phase 1 clinical trials of … Continue reading Scoring Tool Helps Doctors Select Mesothelioma Patients for Clinical Trials »

Compound in Pacific Sea Squirt Kills Mesothelioma Cells

There is new evidence that compounds isolated from a sea squirt found in the waters off of the Indonesian coast may hold the key to fighting mesothelioma and several other malignancies. The potential anticancer and antimicrobial properties are found in polysulfur aromatic alkaloids found in a Pacific sea squirt whose scientific name is Lissoclinum badium. In a new article in the Journal of Natural Products, … Continue reading Compound in Pacific Sea Squirt Kills Mesothelioma Cells »

New Drug Delivery System Doubles Mesothelioma Survival

A new method for delivering cancer-fighting drugs directly into mesothelioma tumors has been shown to more that double mesothelioma survival in a new animal study. Surgeons, pathologists, biomedical engineers and chemists from Boston University and Harvard Medical School used specially-formulated expanding nanoparticles to deliver high doses of the drug paclitaxel into mice with malignant mesothelioma. By loading the drug into nanoparticles that expand in the … Continue reading New Drug Delivery System Doubles Mesothelioma Survival »

African Plants May Offer New Ways to Treat Mesothelioma

Could compounds found in African plants hold the key to fighting intractable malignant mesothelioma? That is the suggestion of a new study conducted by an international team of researchers including scientists in Cameroon and Kenya. The study published in a recent issue of BMC Pharmacology and Toxicology, focused on naturally occurring quinones, organic compounds found in bacteria, certain fungi, and in various plants, including some … Continue reading African Plants May Offer New Ways to Treat Mesothelioma »

Immunotherapy Drug May Be New Option for Recurrent Mesothelioma

There may be new hope for malignant mesothelioma patients whose cancer recurs after treatment. A presentation at the recent World Lung Cancer conference in Vienna earlier this month suggests that the immunotherapy drug nivolumab (brand name Opdivo) could help people with pleural mesothelioma who have run out of treatment options. The author of the new study says his Amsterdam-based team has recorded mesothelioma survival of … Continue reading Immunotherapy Drug May Be New Option for Recurrent Mesothelioma »

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