Treatment Details – 14.8 months

Survival: 14.8 months
Toxicity Grade: 4
Treatments: Chemotherapy
Drugs: Paraplatin
Country: United Kingdom
City/State/Province: Newcastle Upon Tyne
Hospital: Newcastle General Hospital
Journal: Link
Date: 8/2002

Patients: This Phase I study involved 27 patients with malignant pleural mesothelioma. None of these patients had received prior chemotherapy.

Treatment: The treatment consisted of two chemotherapy drugs, pemetrexed and carboplatin (paraplatin).

Toxicity: Toxicities included hematologic (grade 3-4), and grade 1-3 nausea, vomiting, diarrhea, and stomatitis.

Results: Median survival time was 451 days (14.8 months).

Correspondence: Andy Hughes, MD, PhD