Treatment Details – 14.8 months

Survival: 14.8 months
   
Toxicity Grade: 4
   
Treatments: Chemotherapy
   
Drugs: Paraplatin
Pemetrexed
Country: United Kingdom
   
City/State/Province: Newcastle Upon Tyne
   
Hospital: Newcastle General Hospital
   
Journal: Link
   
Date: 8/2002

Description:
Patients: This Phase I study involved 27 patients with malignant pleural mesothelioma. None of these patients had received prior chemotherapy.

Treatment: The treatment consisted of two chemotherapy drugs, pemetrexed and carboplatin (paraplatin).

Toxicity: Toxicities included hematologic (grade 3-4), and grade 1-3 nausea, vomiting, diarrhea, and stomatitis.

Results: Median survival time was 451 days (14.8 months).

Correspondence: Andy Hughes, MD, PhD
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