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Chemotherapy – University of Chicago Medical Center – USA
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Description: |
Patients: This Phase II study involved 17 patients with malignant mesothelioma.
Treatment: The treatment consisted of the chemotherapy drug, gemcitabine. Toxicity: Two patients died without documentation of progressive disease and at least one of these deaths was considered related to drug toxicity and disease progression. In addition, grade 3-4 toxicities included hematologic, infection, dyspnea, edema, malaise/fatigue, cerebellar, cardiac dysrhythmia, and hyponatremia. Results: There were no complete or partial responses and the median survival time was 4.7 months. Correspondence: Hedy L. Kindler, MD |