Chemotherapy – Ohio State University Comprehensive Cancer Center

Survival: 4.9 months
Toxicity Grade: 5
Treatments: Chemotherapy
Drugs: Xeloda
Country: United States
City/State/Province: Columbus, Ohio
Hospital: Ohio State University Comprehensive Cancer Center
Journal: Link
Date: 5/2004


Patients: This Phase II study involved 27 patients with malignant mesothelioma.

Treatment: The treatment consisted of the administration of the chemotherapy drug, capecitabine (xeloda),

Toxicity: One patient died of treatment related diarrhea, dehydration, fever and neutropenia. Other grade 3-4 toxicities included hematologic, hypertension, fatigue, dermatological, anorexia, dehydration, diarrhea, nausea, stomatitis/pharyngitis, infection, and pain.

Results: Median survival was 4.9 months.

Correspondence: Gregory A. Otterson, MD

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