Survival:6.6 months
Toxicity Grade:4
Treatments:Chemotherapy
Drugs:Leucovorin
Country:United States
City/State/Province:Chicago, Illinois
Hospital:University of Chicago Medical Center
Journal:Link
Date:11/1999
Description
Patients: This Phase II study involved 20 patients with malignant mesothelioma who could not be treated by surgery or radiation alone.

Treatment: The treatment consisted of administration of the drug edatrexate with leucovorin.

Toxicity: Grade 3-4 toxicities included hematologic, infection, muscositis, esophagitis/dysphagia, dermatologic, anorexia, malaise/fatigue, cardiac, pulmonary, hepatic, and neurologic.

Results: The median survival duration was 6.6 months.