Immunotherapy – St. Bartholomew’s Hospital – Treatment Details

Survival: 9.0 months
Toxicity Grade: 2
Treatments: Immunotherapy
Drugs: Proleukin
Country: United Kingdom
City/State/Province: London
Hospital: St. Bartholomew’s Hospital
Journal: Link
Date: 1/2001


Patients: This Phase II study involved 29 patients with malignant pleural mesothelioma. None of these patients had been administered previous chemotherapy or immunotherapy.

Treatment: The treatment consisted of the administration of human recombinant Interleukin-2.

Toxicity: Toxicities included fever (grade 2), cutaneous toxicity, nausea and vomiting (grade 1), and chest pains.

Results: Overall median survival was 9 months from the date of first treatment.

Support: The cost of the interleukin-2 was subsidized by Chiron UK Limited. Chiron manufactures interleukin-2 (Proleukin).

Correspondence: R.M. Rudd, MD

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