Treatment Details – 9.6 months

Survival: 9.6 months
  
Toxicity Grade:5
  
Treatments: Chemotherapy
  
Drugs:
Country:United States
  
City/State/Province:Chicago, Illinois
  
Hospital:University of Chicago Medical Center
  
Journal:Link
  
Date: 11/1999

Description:
Patients: This Phase II study involved 20 patients with malignant mesothelioma who could not be treated by surgery or radiation alone.

Treatment: The treatment consisted of administration of the drug edatrexate.

Toxicity: Four patients died without documentation of progressive disease. These deaths involved neutropenic sepsis, cardiac arrest, and respiratory failure from progressive mesothelioma. Grade 3-4 toxicities included hematologic, infection, nausea, emesis, muscositis, esophagitis/dysphagia, dermatologic, anorexia, malaise/fatigue, cardiac, pulmonary, renal, hepatic, and neurologic.

Results: The median survival duration was 9.6 months.

Get your free copy of
“Surviving Mesothelioma” Today!