Lung Cancer or Mesothelioma? BAP1 May be Key

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A team of top mesothelioma researchers say there may be a better way to distinguish malignant mesothelioma from lung cancer (carcinoma). While lung carcinoma and pleural mesothelioma are both malignancies, mesothelioma can grow and spread differently and may respond better to different types of treatment than lung carcinoma. Unfortunately, the two cancers can be difficult to differentiate […]

Novel Mesothelioma Treatment is Based on Marine-Derived Compound

Lab Tech

A new drug based on a compound derived from sea creatures may make an effective second-line treatment for patients with malignant pleural mesothelioma. Most people who are diagnosed with mesothelioma will be treated with a chemotherapy combination that includes pemetrexed (Alimta) and the platinum-based drug cisplatin. But, although pemetrexed/cisplatin is the gold standard for treating the asbestos […]

Investigational Mesothelioma Drug to be Tested in Human Patients

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Researchers in Japan say they are about to start the first clinical trial of an investigational mesothelioma drug that has shown promise in animals. The drug is a monoclonal antibody called YS110 that targets a protein called CD26. CD26 is believed to play a role in mesothelioma tumor growth and invasion and in the process […]

Online Support for Mesothelioma Survivors: What’s Working Now


Remote support groups, including phone and Internet components, offer a unique way to help mesothelioma patients and caregivers – even when they’re not in session. That’s the finding of a new study conducted by researchers at Columbia University, the Mesothelioma Applied Research Foundation, and Maimonides Medical Center in New York. The researchers found that online […]

Three-Drug Combo May Be New Standard-of-Care for Mesothelioma Treatment


The standard of care for people with malignant pleural mesothelioma may be changing for the first time since pemetrexed (Alimta) was approved more than a decade ago. The 27 member cancer centers of National Comprehensive Cancer Network have amended their mesothelioma treatment guidelines to include the monoclonal antibody bevacizumab (Avastin) as part of first-line therapy […]

Tests Reveal Potential New Gene Target for Mesothelioma Therapy

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A gene known as P2X7R (or P2RX7) and the protein that it encodes may offer a novel target for a new kind of mesothelioma therapy. A recent study of P2X7R at the University of Ferrara in Ferrara, Italy found that the protein was overexpressed in three different mesothelioma cell lines. Just as importantly, P2X7R was […]

Mesothelioma Chemotherapy May Get a Boost from Leukemia Drug

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There is new evidence that a drug designed to treat leukemia may help boost the effectiveness of the most popular chemotherapy drug for malignant mesothelioma. Pemetrexed (Alimta) was approved by the FDA in 2004 and remains the only drug specifically approved for the treatment of mesothelioma, a virulent cancer closely linked to asbestos exposure. Although […]

Mesothelioma Symptoms: Best Management for Pleural Effusion

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An international team of scientists is hoping to finally be able to answer the question of how often mesothelioma patients with pleural effusion should have their indwelling pleural catheters drained. Indwelling pleural catheters (IPCs) are a novel way to treat the bothersome mesothelioma symptoms caused by a buildup of excess fluid in the space around the […]

Australian Aboriginals Have World’s Highest Mesothelioma Rate


The Aboriginal people of Western Australia have the highest per capita incidence of malignant mesothelioma in the world according to a new article in the Australian and New Zealand Journal of Health. A now-closed asbestos mine may be to blame. Malignant mesothelioma is a lethal and fast-growing cancer of the membranes around the heart, lungs […]

Influences on Survival After Radical Mesothelioma Surgery

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Yet another new study is raising questions about the advisability of radical surgery for people with malignant pleural mesothelioma. Reporting in the European Journal of Cardiothoracic Surgery, a group of Italian doctors say preexisting conditions, as well as an infection called pleural sepsis, may be the biggest limiters to mesothelioma survival after extrapleural pneumonectomy. The Mesothelioma […]