The Challenge of Diagnosing Malignant Mesothelioma

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The case of a Japanese man whose mesothelioma went undetected until it claimed his life seven months later highlights the need for better and earlier mesothelioma diagnosis. The man is the subject of a new article published in the medical journal Case Reports in Oncology. Although the patient complained of chest pain for months, his [...]

Second Surgery May Prolong Mesothelioma Survival


There is new evidence that surgery may be the most effective type of second-line treatment for malignant pleural mesothelioma. First-line therapies for malignant mesothelioma include surgery, chemotherapy, radiation and experimental approaches such as immunotherapy. However, the waters become murkier after mesothelioma recurrence. There is no widely-accepted second-line treatment protocol for mesothelioma. Facts About Mesothelioma Relapse [...]

Trimodal Mesothelioma Treatment May Not Be Worth the Risk


Japanese researchers say trimodality treatment for mesothelioma that includes chemotherapy, extrapleural pneumonectomy (EPP), and post-surgical radiation may not be beneficial enough to justify the risk. Pleural mesothelioma is one of the most difficult cancers to treat because it grows quickly and is resistant to most conventional therapies. Most mesothelioma patients have to have a combination of [...]

New Method Could Help Identify Best Candidates for Mesothelioma Surgery

Surgery for Peritoneal Mesothelioma

Peritoneal mesothelioma patients with high levels of a certain protein may not be good candidates for mesothelioma surgery. Italian researchers came to that conclusion after evaluating the medical records of 117 patients with peritoneal mesothelioma. The patients had all undergone the gold standard mesothelioma treatment of cytoreductive surgery (CRS) followed by heated intraperitoneal chemotherapy (HIPEC). [...]

Study Finds Molecular and Clinical Gender Differences in Mesothelioma

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Malignant pleural mesothelioma may act differently in men and women due to differences at the molecular level. Researchers in some of the nation’s top medical centers say understanding these gender-specific mesothelioma traits may lead to new and better treatments. “Insight into the survival advantage of female patients may advance the molecular understanding of malignant pleural [...]

Fighting Mesothelioma with Immunotherapy Drug Tremelimumab


A new study on the immunotherapy drug tremelimumab for the treatment of mesothelioma has some good news and some bad news for mesothelioma patients and families. According to the UK authors of the new report, a number of studies indicate that tremelimumab shows promise as a potential new therapy for mesothelioma. On the other hand, [...]

Enzyme Blockers May Offer Innovative New Mesothelioma Treatment


Cancer drugs that block an enzyme called EZH2 could be a “tremendous innovation” for mesothelioma patients, according to researchers at Memorial Sloan Kettering Cancer Center in New York. Recent research on mice at Memorial Sloan Kettering found that elevated levels of EZH2 allowed mesothelioma to grow out of control and that blocking the enzyme inhibited [...]

Radiation Treatment After Mesothelioma Surgery: Is it Worth It?


Radiotherapy after lung-removing mesothelioma surgery is not likely to improve mesothelioma survival or quality of life. European researchers reached that conclusion after the first Phase II randomized trial of postoperative hemithoracic (one-sided) radiotherapy in mesothelioma treatment. Multimodal Mesothelioma Treatment Because mesothelioma is both aggressive and highly resistant to conventional cancer therapies, most patients undergo several [...]

Mesothelioma Patients May Avoid Chemotherapy Rash with This Medicine

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Patients undergoing chemotherapy for mesothelioma may avoid the rash associated with the chemotherapy drug pemetrexed if they take a small amount of a corticosteroid drug for the first three days of treatment. Doctors at Tokushima University in Japan reviewed the cases of mesothelioma patients on chemotherapy who were treated with the corticosteroid dexamethasone with good [...]

What is the Best Approach to Surgery for Mesothelioma?

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What is the best way to approach surgery for malignant pleural mesothelioma? Do more and better research. That proclamation comes from a top researcher and cardiothoracic surgeon with University College London. Tom Treasure, MD, a professor in the Clinical Operational Research Unit, says current research is not sufficient to prove what type of mesothelioma surgery [...]