Uncovering the Secrets of Long-Term Survival in Pleural Mesothelioma: The DNA Repair Factor

Uncovering the Secrets of Long-Term Survival in Pleural Mesothelioma: The DNA Repair Factor

ByHolly Zink

DNA repair plays an important role in a type of cancer called malignant pleural mesothelioma. Scientists have found that mesothelioma patients who live for a very long time do not have active DNA repair function. Exploring Longevity in Malignant Pleural Mesothelioma Mesothelioma is a type of cancer that develops from the thin layer of tissue that covers many of the body’s internal organs. Pleural mesothelioma grows in the lining of the lungs. There are about 2,000 cases of pleural mesothelioma each year in the United States. Mesothelioma is caused by exposure to asbestos. This is a toxic material that has been used in construction, manufacturing, and many other applications. This type of cancer is hard to treat, and doctors often…

HIPEC Treatment: Heating Up the Fight Against Mesothelioma
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HIPEC Treatment: Heating Up the Fight Against Mesothelioma

ByHolly Zink

An elderly woman with malignant mesothelioma had a positive response to HIPEC treatment. HIPEC  stands for hyperthermic intraperitoneal chemotherapy. The Journey of Diagnosing Malignant Peritoneal Mesothelioma Mesothelioma is a type of cancer that is caused by exposure to asbestos. It develops in the lining of organs in the body. When it grows in the abdominal cavity, it is called malignant peritoneal mesothelioma. This type of mesothelioma causes symptoms like abdominal pain, bloating, weight loss, and fluid build-up in the abdomen. It can take decades after asbestos exposure for mesothelioma symptoms to appear, and it can be hard for doctors to diagnose this cancer. Triumph Over Malignant Peritoneal Mesothelioma with HIPEC In this case, a 64-year-old woman went to the hospital…

Exploring a New Cell-Based Therapy to Treat Mesothelioma
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Exploring a New Cell-Based Therapy to Treat Mesothelioma

ByHolly Zink

Mesothelioma, an asbestos-related cancer, can be very difficult to treat. But researchers have a new model for a cell-based therapy with Paclitaxel. New results were recently published in Biochemical Pharmacology. Mesothelioma Treatment Malignant mesothelioma is a very aggressive cancer. Pleural mesothelioma is a type of cancer that develops from the thin layer of tissue that covers the lungs and chest wall. It can often take around 40 years for pleural mesothelioma to be diagnosed. Imaging studies such as X-rays or CT scans may help in the diagnosis, but a tissue biopsy usually confirms the disease. In this latest study, researchers used two tools. They used a group of human cells called mesenchymal stromal cells. And, they used Paclitaxel, a medicine…

Cracking the Code: Revolutionizing Mesothelioma Staging
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Cracking the Code: Revolutionizing Mesothelioma Staging

ByHolly Zink

A group of researchers from the International Association for the Study of Lung Cancer (IASLC) teamed up to help us understand this disease better. The IASLC developed a mesothelioma database to improve disease staging. Staging is important because it helps doctors plan the best treatment The Power of Data and International Collaboration Malignant pleural mesothelioma is a complex disease. Mesothelioma diagnosis and accurate staging are often difficult to pin down. And the diagnosis is further complicated by different disease subtypes. When doctors talk about mesothelioma, they often mention staging. Doctors use staging to give an idea of how big the cancer is and if it has spread to other parts. They might use numbers like 1, 2, 3, or 4 to…

Breakthrough in Mesothelioma Treatment: Cellectis’ Promising CAR-T Therapy
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Breakthrough in Mesothelioma Treatment: Cellectis’ Promising CAR-T Therapy

ByHolly Zink

Mesothelioma is a challenging cancer with limited treatment options. Yet, recent advancements in CAR-T therapy are bringing new hope to the table. There is a breakthrough that holds the potential for improving mesothelioma treatment outcomes. Data comes from Journal for ImmunoTherapy of Cancer. CAR-T Therapy: A New Frontier for Mesothelioma CART T-cell therapy for mesothelioma is a type of immunotherapy. It starts with T-cells from the patient’s blood. Scientists alter the cells to recognize certain antigens on the surface of cancer cells. Then they give them back to the patient. In the case of mesothelioma, the main targeted antigen is mesothelin. Mesothelioma patients tend to produce extra mesothelin. This protein helps drive the growth and spread of their cancer. People with high levels…

How Inflammation, Stress, and Signaling Shape Mesothelioma’s Growth
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How Inflammation, Stress, and Signaling Shape Mesothelioma’s Growth

ByHolly Zink

Scientists are looking at how long-term inflammation, cell stress, and messed-up cell signaling help mesothelioma cancer cells grow and spread. By looking at these processes in mesothelioma patients, the scientists can learn more about new ways to treat this aggressive cancer. Revolutionizing Mesothelioma Treatment Malignant mesothelioma is a type of cancer that develops from the thin layer of tissue that covers many of the body’s internal organs. When it grows in the lining of the lungs, it is called pleural mesothelioma. There are about 2,000 cases of pleural mesothelioma in the United States each year. Mesothelioma is linked to exposure to a toxic mineral called asbestos. It can take decades for symptoms of mesothelioma to appear after a person is…

Mesothelioma Treatment Roadmap: Connecting Chemotherapy Response and Surgical Outcomes
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Mesothelioma Treatment Roadmap: Connecting Chemotherapy Response and Surgical Outcomes

ByHolly Zink

Mesothelioma patients who do not respond well to chemotherapy before surgery are likely to have poor outcomes after the procedure. This is the finding of a group of researchers from the University of Texas MD Anderson Cancer Center. How Chemotherapy Response Shapes Mesothelioma Surgery Outcomes Mesothelioma is a rare type of cancer that is hard to diagnose and treat. It develops from the thin layer of tissue that covers many of the body’s internal organs. Mesothelioma is caused by exposure to a toxic mineral called asbestos. In most cases, doctors will use more than one type of treatment to remove as many cancer cells as possible from a patient’s body. The standard therapies include chemotherapy, radiation, and surgery. Of all…

Unveiling the Mesothelioma Risk Posed by Exposure to Asbestos
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Unveiling the Mesothelioma Risk Posed by Exposure to Asbestos

ByHolly Zink

Asbestos is a toxic mineral found naturally throughout the world. Exposure to asbestos can cause people to develop mesothelioma, which is a rare and aggressive cancer. A new study looked how the risk for developing mesothelioma and lung cancer for people who live around asbestos in Tehran, Iran. Asbestos: A Fireproof, Deadly Fiber Even though asbestos is toxic to humans, people have used it in many industries because of its special qualities. It is almost impossible to set it on fire, it is nearly impossible to corrode, and it is composed of fibers so that it can be woven into other materials. It is also cheap because it can be taken out of the ground and does not have to…

Empowering Mesothelioma Patients with Patient-Reported Symptom Monitoring
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Empowering Mesothelioma Patients with Patient-Reported Symptom Monitoring

ByHolly Zink

New data shows that patient-reported symptom monitoring improves the quality of life in lung cancer patients. The study was published in the Journal of the National Cancer Institute. Enhancing Life Quality for Lung Cancer Patients Pleural mesothelioma is an asbestos-related cancer that affects the lungs. Mesothelioma patients have many of the same symptoms as lung cancer patients. Among other things, they tend to suffer from breathing problems, chest pain, cough, weakness, and fatigue. One recent study focused on how patients’ lives can be improved during and after lung cancer treatment. Researchers were interested in using “patient-reported outcomes measures.” Or PROMs for short. PROMS can monitor how patients are feeling. These PROMs would help keep track of symptoms and make sure that…

New Hope for Mesothelioma Patients in Intensive Care
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New Hope for Mesothelioma Patients in Intensive Care

ByHolly Zink

In the fight against mesothelioma, there’s new and hopeful data that might help patients who end up in the intensive care unit (ICU). A recent study gives us important details about how some patients are getting better, and this is good news for people around the world. ICU Success for Mesothelioma Patients Mesothelioma is a rare kind of cancer caused by asbestos. It mostly affects the lining of the lungs and chest. This can lead to problems like trouble breathing, chest pain, coughing, and feeling tired a lot. But what happens when mesothelioma patients have a very serious health issue and need to go to the ICU? We know that 5% of cancer patients have to go to the ICU…