Dentists Exposed to Asbestos Could Trigger Malignant Mesothelioma

Dentists Exposed to Asbestos Could Trigger Malignant Mesothelioma

Experts have recommended a new plan to warn dentists exposed to asbestos. Asbestos is a naturally occurring mineral that has been found throughout the world. Asbestos is toxic and cancer-causing for human beings. Dentists used asbestos in the manufacture of dental prostheses from the 1960s to 1970s. Generally, those who develop asbestos-related diseases show no signs of illness for a long time after their exposure. It can take from 10 to 40 years or more for symptoms of an asbestos-related condition to appear. Experts have recommended a new plan to prevent asbestos exposure in dentistry. This recommendation was created under the EuropeAid Assessment Guidelines. Experts also request the inclusion of the dental sector in the lists of professions with asbestos exposure. … Continue reading Dentists Exposed to Asbestos Could Trigger Malignant Mesothelioma »

New Drug Targeting Fibrosis may Help Mesothelioma Patients

Targeting Fibrosis in Mesothelioma has Therapeutic Benefits

Targeting fibrosis has therapeutic benefits in mesothelioma. Most drugs have limited effects in difficult-to-treat cancers such as mesothelioma. Often this is because not enough of the drug can get into the tumor to generate an anti-tumor effect. Fibrosis is a common element of mesothelioma. It causes the area around the cancer to stiffen. Fibrosis acts as a barrier, stopping drugs from getting into the cancer tumor. This limits the immune system’s ability to detect and access the tumor to kill it. A new study is looking at how a family of proteins called lysyl oxidases can help solve this problem. These proteins are associated with fibrosis in many cancers, including mesothelioma. Oncologists targeting fibrosis and this protein family may improve … Continue reading New Drug Targeting Fibrosis may Help Mesothelioma Patients »

Precision Medicine Treatment: Gene-Targeting Mesothelioma

Precision Medicine Treatment: Gene-Targeting Mesothelioma

A new precision medicine treatment for mesothelioma comes from scientists in Italy. This form of mesothelioma occurs after asbestos exposure in people with a genetic mutation. The mutation is represented by patients with an inherited cancer syndrome. These patients typically have an even worse prognosis than other mesothelioma patients. But the Italian team came up with a way to target the mutated gene. This form of treatment is called precision medicine. Precision medicine treatment looks at the genetics of a patient to select a treatment that will work best for them. Discovery of a DNA Gene Mutation Malignant pleural mesothelioma is a rare and aggressive cancer caused by exposure to asbestos. Malignant mesothelioma is one of the most aggressive kinds … Continue reading Precision Medicine Treatment: Gene-Targeting Mesothelioma »

Asbestos Exposure in Construction Workers Leads to Mesothelioma

Asbestos Exposure in Construction Workers Leads to Mesothelioma

Asbestos exposure in construction workers remains a particular concern. Malignant mesothelioma is a rare cancer with a global incidence. Italy is among the countries with the highest values of mesothelioma. Mesothelioma is associated with exposures to asbestos fibers and other asbestiform fibers. Asbestos exposure in construction workers remains a particular concern. A new study describes the characteristics of Italian malignant mesothelioma cases among construction workers. Scientists analyzed 31,572 cases with definite asbestos exposure in the period from 1993 to 2018. Connecting Asbestos Exposure and Mesothelioma in Construction Workers The relation between asbestos use and the historical trend of mesothelioma is clear. Italian scientists assessed asbestos exposure in 78.2% of the mesothelioma cases. This accounts for 24,864 of the patients studied. … Continue reading Asbestos Exposure in Construction Workers Leads to Mesothelioma »

Top Three Factors Predicting Mesothelioma Survival are Age, Histological Type, and Surgery Status

Top Three Factors Predicting Mesothelioma Survival

Malignant pleural mesothelioma is a rare and aggressive malignancy with a dismal prognosis. A new study is predicting mesothelioma survival among male and female patients in the United States. Identifying factors “associated with mesothelioma mortality is important research given the poor prognosis” according to Dr. Bian Liu from the a Icahn School of Medicine at Mount Sinai in New York. A new study applied a machine-learning algorithm to 12,210 patients to predict survival. The top three factors were age, histological type, and cancer-directed surgery status. Analyzing Over 12,000 Mesothelioma Patients Scientists from the New York State Department of Health included 12,210 mesothelioma patients. They involved only malignant pleural mesothelioma patients. They excluded cases with unknown diagnostic confirmation and unknown survival … Continue reading Top Three Factors Predicting Mesothelioma Survival are Age, Histological Type, and Surgery Status »

Two New Diagnostic Tissue Biomarkers Discovered for Mesothelioma

Identifying Two New Diagnostic Tissue Biomarkers for Mesothelioma

Scientists have now identified two new diagnostic tissue biomarkers for malignant pleural mesothelioma. Doctors identify mesothelioma using diagnostic tissue biomarkers. This is called immunohistochemistry. The use of immunohistochemistry improves the accuracy of mesothelioma diagnosis in clinical practice. Yet, new methods for discovering diagnostic markers are still needed. Following a Reverse Approach in a Rare Case Mesothelioma is usually diagnosed after a person experiencing symptoms goes to a doctor. One thing a doctor may do is perform a tissue biopsy. The doctor will remove a part of the tissue (suspected mesothelioma) for examination. Most tissue biopsies are done with a needle and then examined in a laboratory. The lab will look for specific biomarkers to find out if the tissue contains … Continue reading Two New Diagnostic Tissue Biomarkers Discovered for Mesothelioma »

New Artificial Intelligence Tool Measures Mesothelioma Tumors

New Artificial Intelligence Tool Measures Mesothelioma Tumors

A new artificial intelligence tool can measure mesothelioma tumors without any human input. Automated mesothelioma tumor measurement is now possible. The artificial intelligence algorithm performed well. There were 266 malignant pleural mesothelioma tumors analyzed. This is the largest study of its kind performed in mesothelioma. And this is the first description of an automated artificial intelligence tool. Inconsistent Mesothelioma Measurement During Clinical Assessment In malignant pleural mesothelioma, complex tumors result in inconsistent clinical assessment. Promising new methods need practical computer automation methods. A new publication showed an automated tool for this purpose. This study compared a new artificial intelligence tool with human standard clinical assessment. This study looked at mesothelioma patients treated with chemotherapy. Evaluating How Well the New Tool … Continue reading New Artificial Intelligence Tool Measures Mesothelioma Tumors »

Mesothelioma Patients with Coronavirus: Artificial Intelligence to Provide Best Treatment Plan

Mesothelioma Patients with Coronavirus and Artificial Intelligence

Mesothelioma patients are vulnerable to the coronavirus due to their poor immune response. Artificial intelligence can provide information used to treat cancer patients diagnosed with coronavirus. Hospitals have access to real-time data from cancer patients. Artificial intelligence uses this data to predict the severity of the patient’s risk. And, it can help physicians alter or change their treatment plans. A mix of treatment therapies can heal mesothelioma patients with coronavirus. Artificial intelligence can predict a patient’s treatment plan to increase survival rates. Coronavirus Disrupts Normal Treatment Plans The coronavirus pandemic has caused chaos throughout the world. The key threat of the coronavirus is in immune-compromised mesothelioma patients. Their weakened immune response makes them weak and at risk. Oncologists and their … Continue reading Mesothelioma Patients with Coronavirus: Artificial Intelligence to Provide Best Treatment Plan »

Mesothelioma Mimics Ovarian Cancer: Lessons from a Case Report

Mesothelioma Mimics Ovarian Cancer: Lessons from a Recent Case Report

Mesothelioma mimics ovarian cancer in a new report by Radiology Case Reports. Mesothelioma is a rare and very aggressive tumor of the peritoneum. Similar clinical and imaging presentations mean mesothelioma mimics ovarian cancer at times. Yet, a history of asbestosis exposure is key as the main risk factor for mesothelioma. Imaging plays a key role in getting the diagnosis correct. It narrows down the diagnosis possibilities. Ultrasound-guided biopsy with histological study can confirm a mesothelioma diagnosis. Case Report Misdiagnosis The Bangladesh National Institute of Oncology recently published a case report. A 42-year-old woman reported pelvic pain and progressive abdominal distension. An abdominal ultrasound revealed a high volume anechoic peritoneal effusion. Further investigation showed extensive peritoneal disease and bilateral ovarian tissue … Continue reading Mesothelioma Mimics Ovarian Cancer: Lessons from a Case Report »

Research Advancements Audit by Asbestos Diseases Research Institute

Research Advancements Audit by Asbestos Diseases Research Institute

Research advancements provide a brighter future for malignant pleural mesothelioma patients. Pleural mesothelioma is an aggressive cancer of the lung lining. Mesothelioma is associated with asbestos exposure. Australian researchers from the Asbestos Diseases Research Institute and the University of Sydney have reviewed the basic research advancements. Their new publication covers mesothelioma biomarkers and treatment strategies. There is a long latency period from asbestos exposure to cancer development. A lack of genetic biomarkers makes early diagnosis difficult. The prognosis of pleural mesothelioma is poor. There is an average survival of eight to fourteen months following diagnosis. Diagnostic Biomarkers Biomarkers are limited in the clinic to diagnose pleural mesothelioma. A biomarker is a biological molecule found in blood or other body fluids … Continue reading Research Advancements Audit by Asbestos Diseases Research Institute »

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