Experimental Mesothelioma Treatment Targets Tumor Growth Compounds

Experimental mesothelioma treatment

Hong Kong researchers have released the first results of an experimental mesothelioma treatment they are working on. The treatment targets organic compounds believed to contribute to mesothelioma growth. The trial took place at the University of Hong Kong. Mice with mesothelioma received doses of an enzyme inhibitor called DFMO. The drug appears to stop the production of organic compounds called polyamines. In tests, mice with lower polyamine levels lived longer with pleural mesothelioma. Enzymes Contribute to Tumor Growth The growth and spread of pleural mesothelioma is a complex process. It involves many different proteins and enzymes working together. Scientists have not yet identified all of the compounds that contribute to cancer growth. But the experimental mesothelioma treatment in Hong Kong … Continue reading Experimental Mesothelioma Treatment Targets Tumor Growth Compounds »

PIPAC May Make More Patients Candidates for Mesothelioma Surgery

candidates for mesothelioma surgery

Researchers in France have come up with a way to turn some people with inoperable peritoneal mesothelioma into good candidates for mesothelioma surgery.  They are using a new technique to spray chemotherapy drugs directly onto peritoneal tumors in order to shrink them.  In some cases, the technique shrunk mesothelioma tumors enough that they could be surgically removed with the CRS/HIPEC procedure.  What Makes a Good Candidate for Mesothelioma Surgery A number of factors influence whether patients are good candidates for mesothelioma surgery. Patients have to be in otherwise reasonably good health so that their body can handle the surgery. It is also critical that their mesothelioma not be so widespread in their abdomen that it would be impossible for surgeons … Continue reading PIPAC May Make More Patients Candidates for Mesothelioma Surgery »

New Study Suggests Music May Offer Relief from Mesothelioma Pain

relief from mesothelioma pain with music

There is new evidence that listening to music might offer some relief from mesothelioma pain and fatigue. A new study in the European Journal of Cancer Care details a 6-month experiment on the effects of music on cancer pain, anxiety, and fatigue.  Cancer patients listened to music at home five times a week. The results show that many of them started to feel better after just six weeks. Finding Relief from Mesothelioma Pain Pain is a common symptom of malignant mesothelioma, especially as the disease progresses. Patients with pleural mesothelioma have cancer on the lining around their lungs. These patients may experience symptoms such as shortness of breath, coughing, and chest pain. Patients with peritoneal mesothelioma have cancer on the … Continue reading New Study Suggests Music May Offer Relief from Mesothelioma Pain »

Antioxidant Supplements for Mesothelioma Patients Might be Dangerous

antioxidant supplements for mesothelioma patients

Two separate lung cancer studies suggest that antioxidant supplements for mesothelioma patients may not be advisable.  The studies appear in the most recent issue of the medical journal Cell.  Both focus on the role of antioxidants in the growth and spread of lung cancer. Although mesothelioma is not the same as lung cancer, it affects the same area of the body and shares many of the same characteristics.  The new research suggests that, instead of fighting cancer, antioxidant supplements for mesothelioma patients, might actually help it grow.  Supplements for Cancer Patients Antioxidant vitamins like A, C, and E are plentiful in fruits and vegetables. Many people take antioxidant supplements to make up for a poor diet. These vitamins can help … Continue reading Antioxidant Supplements for Mesothelioma Patients Might be Dangerous »

Breath Testing for Mesothelioma: Not Yet Ready for Widespread Use?

breath testing for mesothelioma

Breath testing for mesothelioma may be a promising new way to catch asbestos cancer early. But Italian researchers are warning that there is not yet enough research to recommend widespread use of the technique. Malignant pleural mesothelioma is a virulent and hard-to-treat cancer. Researchers around the world continue to search for faster, easier ways to diagnose and treat it. Breath testing for mesothelioma is one proposed method. Special machines measure volatile organic compounds (VOCs) in patients’ exhaled breath. VOCs can give doctors important information about cellular metabolism and can indicate the presence of cancer. But researchers at Italy’s University of Bari analyzed all of the studies on breath testing for mesothelioma since 2000. They say none of the studies are … Continue reading Breath Testing for Mesothelioma: Not Yet Ready for Widespread Use? »

Exposed to Asbestos? Lung Fluid Test May Waste Valuable Time

exposed to asbestos worker

If you have been exposed to asbestos and your doctor sees a mesothelioma tumor on your CT scan, it may be a waste of time to do a lung fluid test, too. Many different types of cancer cause excess lung fluid or pleural effusions. Looking for cancer cells in pleural effusions is one of the ways doctors test for cancers like pleural mesothelioma. This is called effusion cytology. But a new study says this test may not be very reliable for people with malignant mesothelioma. If other factors point to mesothelioma, they say it makes more sense to skip effusion cytology and go straight to a biopsy. Mesothelioma Develops in People Exposed to Asbestos Pleural mesothelioma is a type of … Continue reading Exposed to Asbestos? Lung Fluid Test May Waste Valuable Time »

Mesothelioma Chemotherapy with Avastin Helps Pain, Neuropathy

mesothelioma chemotherapy with Avastin

New evidence suggests that supplementing standard mesothelioma chemotherapy with Avastin (bevacizumab) may lead to less pain. It may also reduce the risk of another mesothelioma complication called peripheral neuropathy. That word comes from a newly-published study involving several French hospitals. The study is a follow-up to the French-led MAPS study from 2016. The MAPS study showed that performing mesothelioma chemotherapy with Avastin – in addition to the standard chemotherapy drugs – improved mesothelioma survival by 23 percent. Now it looks like the three-drug combination can also help mesothelioma patients live longer with fewer side effects. Mesothelioma Complications and Side Effects Avastin is a VEGF inhibitor. It works by preventing the formation of blood vessels that feed a growing tumor. The … Continue reading Mesothelioma Chemotherapy with Avastin Helps Pain, Neuropathy »

Minimally Invasive Mesothelioma Diagnosis from Lung Fluid

minimally invasive mesothelioma diagnosis

Minimally invasive mesothelioma diagnosis with lung fluid may be just as effective as a tissue biopsy. That’s according to Australian mesothelioma researchers. Australia was once one of the biggest producers of asbestos and now has some of the highest mesothelioma rates in the world. It is also home to high-level mesothelioma research. In the latest study, scientists ran a meta-analysis comparing surgical biopsy with a minimally invasive mesothelioma diagnosis tool called cytology. Their conclusion is that surgery may not always be necessary to diagnose malignant mesothelioma. Tissue Versus Lung Fluid Malignant mesothelioma is a fatal cancer caused by exposure to asbestos. It is challenging to diagnose because the symptoms are often vague and similar to other less serious conditions. Doctors … Continue reading Minimally Invasive Mesothelioma Diagnosis from Lung Fluid »

Case Shows Swallowing Difficulty May Be Among Early Signs of Mesothelioma

early signs of mesothelioma

The case of a Spanish mesothelioma patient suggests that difficulty swallowing can be one of the rarest early signs of mesothelioma. Mesothelioma is a cancer that starts on the membrane lining the chest or abdomen. A swallowing problem – also called dysphagia – is not typically associated with mesothelioma. But a recent article in a Spanish medical journal signals that it might be time to consider this symptom as one of the early signs of mesothelioma.   Knowing the Symptoms of Mesothelioma The two major types of malignant mesothelioma are pleural and peritoneal. Pleural mesothelioma grows on the lining around the lungs. Peritoneal mesothelioma grows on the lining around the abdomen. In people with pleural mesothelioma, chest pain and breathing … Continue reading Case Shows Swallowing Difficulty May Be Among Early Signs of Mesothelioma »

Gel-Based Mesothelioma Treatment: A Novel Approach to Pleural Mesothelioma

gel-based mesothelioma treatment

Swiss scientists are developing a novel gel-based mesothelioma treatment for people with pleural disease. Early studies suggest it may be a safer way to deliver cancer-fighting drugs with fewer side effects. The gel-based mesothelioma treatment combines the chemotherapy drug cisplatin with a natural “glue” called fibrin. When the gel is applied during surgery, it can keep fighting tumors for months. Why Develop a Gel-Based Treatment? Cisplatin is a platinum-based drug. Together with pemetrexed (Alimta), it is one of the most common chemotherapy drugs for mesothelioma. In the past decade, doctors came up with a way to increase the effectiveness of cisplatin in people with peritoneal mesothelioma. These patients get chemotherapy the usual way. But they also get a rinse of … Continue reading Gel-Based Mesothelioma Treatment: A Novel Approach to Pleural Mesothelioma »

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