CRS/HIPEC Treatment Helps Double Survival Among Swedish Mesothelioma Patients

CRS/HIPEC Treatment

A new report suggests that CRS/HIPEC treatment has helped to double the odds of surviving peritoneal mesothelioma in Sweden.  Researchers collected data from the Swedish National Cancer Registry. A total of 102 peritoneal mesothelioma cases were included from two separate 5-year time periods. The report shows that, since CRS/HIPEC treatment was introduced in Sweden, overall survival of peritoneal mesothelioma increased from 7 to 15 months. At 5 years, twice as many peritoneal mesothelioma patients were still alive. The researchers conclude that this is likely due, at least in part, to CRS/HIPEC treatment.  Surviving Peritoneal Mesothelioma Peritoneal mesothelioma is an aggressive cancer that starts on the membrane lining the abdomen. It is almost always caused by accidental swallowing of microscopic asbestos … Continue reading CRS/HIPEC Treatment Helps Double Survival Among Swedish Mesothelioma Patients »

Effect of Chemotherapy on Immunotherapy for Mesothelioma

effect of chemotherapy on immunotherapy

Belgian scientists say they are still not sure about the effect of chemotherapy on immunotherapy for mesothelioma. They reached that conclusion after testing several different chemotherapy drugs on mesothelioma cells in the lab. The combination of chemotherapy and immunotherapy is “chemoimmunotherapy”. It aims to harness the unique powers of each treatment approach. A meta-analysis last May called chemoimmunotherapy the “next frontier” in mesothelioma treatment.  But the new Belgian study on the effect of chemotherapy on immunotherapy highlights how much doctors still do not know about the combo. Immune Checkpoints Are the Key When it is working properly, the immune system is supposed to find and kill cancer cells before they become mesothelioma tumors. But mesothelioma cells can hide from the … Continue reading Effect of Chemotherapy on Immunotherapy for Mesothelioma »

Curcumin Supplement Delays Mesothelioma Tumor Growth in Mice

curcumin supplement

Italian researchers say a curcumin supplement containing a compound found in black pepper slowed the growth of mesothelioma tumors in mice. The commercially available supplement is called Curcumin-C3complex/Bioperine. This is the first time this formulation has been studied for malignant mesothelioma.  Lab-grown human mesothelioma cells stopped growing when scientists treated them with the curcumin supplement. The treatment did the same in live mice.  The researchers suggest that the curcumin supplement may work synergistically with standard treatments.  What is in Curcumin-C3complex/Bioperine? Curcumin is the most bioactive compound in turmeric. Turmeric is the spice that gives curry its bright yellow color.  Several scientific studies suggest that curcumin and other curcuminoid compounds in turmeric have powerful health benefits. These compounds are anti-inflammatory and … Continue reading Curcumin Supplement Delays Mesothelioma Tumor Growth in Mice »

Isolated Thoracic Perfusion for Mesothelioma Symptom Relief

isolated thoracic perfusion for mesothelioma

A new study suggests that a treatment called isolated thoracic perfusion could help alleviate some of the worst symptoms of malignant pleural mesothelioma. Isolated thoracic perfusion is a method for circulating medicine in just one area of the body. When doctors circulated chemotherapy drugs in the chests of people with pleural mesothelioma, their symptoms went away for several months.  Now, the team says it is time to test the technique in a bigger pool of mesothelioma patients.  The Theory Behind ITP Pleural mesothelioma is a membrane cancer that occurs in the chest. Chemotherapy drugs like Alimta can be powerful weapons against pleural mesothelioma. But they can also damage healthy tissues.  When healthy tissues are damaged by chemotherapy, mesothelioma patients can … Continue reading Isolated Thoracic Perfusion for Mesothelioma Symptom Relief »

Risk for Peritoneal Mesothelioma Keeps Rising Decades After Exposure

risk for peritoneal mesothelioma

Pleural mesothelioma risk may level off over several decades, but the risk for peritoneal mesothelioma never goes down. That is the conclusion of researchers at Italy’s University of Eastern Piedmont. It is based on data from more than 50,000 asbestos-exposed Italian workers.   More than 40 years after asbestos exposure, the workers’ risk for peritoneal mesothelioma continued to rise. Calculating Mesothelioma Rates Over Time Asbestos is the primary cause of all types of malignant mesothelioma. Even short-term asbestos exposure raises the risk for peritoneal mesothelioma and pleural mesothelioma. Peritoneal mesothelioma occurs in the lining of the abdomen. Pleural mesothelioma tumors start on the lining around the lungs.  If asbestos fibers are inhaled or swallowed, they embed themselves in these linings. This … Continue reading Risk for Peritoneal Mesothelioma Keeps Rising Decades After Exposure »

Unresectable Peritoneal Mesothelioma Becomes Operable After Bi-Directional Chemotherapy

French researchers have successfully operated on a man with unresectable peritoneal mesothelioma after treating him with bi-directional chemotherapy. Chemotherapy is the most common treatment for unresectable peritoneal mesothelioma. Most mesothelioma patients have chemotherapy by IV infusion. But some cancer centers now offer another chemotherapy delivery method. Intraperitoneal chemotherapy bypasses the bloodstream. It lets doctors put higher doses of cancer-killing medicine at the site of a tumor. The French team combined the two types of chemotherapy in one patient. It shrunk the patient’s unresectable peritoneal mesothelioma tumor enough to perform surgery.  Two Types of Mesothelioma Chemotherapy With IV chemotherapy, medicine travels to the tumor through the bloodstream. It is one way of treating unresectable peritoneal mesothelioma. One drawback of IV chemotherapy … Continue reading Unresectable Peritoneal Mesothelioma Becomes Operable After Bi-Directional Chemotherapy »

Mesothelioma Risk From Home Renovation in The Spotlight

mesothelioma risk from home renovation

The case of an Australian man is highlighting the mesothelioma risk from home renovation when asbestos is present.  Forty-two year old Matthew Werfel recently won a lawsuit against Amaca, the asbestos producer previously known as James Hardie. The company manufactured the asbestos-containing cement sheets that led to Werfel’s pleural mesothelioma. The record $3 million payout is an expensive warning to other DIY homeowners about the potential mesothelioma risk from home renovation. Asbestos in Construction Products Asbestos is a mineral that has to be mined from the ground. As early as the 1930’s, companies like James Hardie recognized its potential value as a construction material. Asbestos is strong, plentiful and resistant to heat and corrosion. It was used for decades to … Continue reading Mesothelioma Risk From Home Renovation in The Spotlight »

Minimally Invasive Lymph Node Staging May Prevent Unnecessary Mesothelioma Surgery

lymph node staging for mesothelioma

A minimally invasive procedure for lymph node staging may help some pleural mesothelioma patients avoid the pain and risk of surgery. That is the conclusion of a recent study on endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA).  EBUS-TBNA is a minimally invasive method for testing the lymph nodes deep in the chest (mediastinal lymph nodes). If lymph node staging shows evidence of pleural mesothelioma, surgery is less likely to be effective.  Mediastinal Lymph Node Staging and Mesothelioma Pleural mesothelioma is a rare cancer that starts on the membrane around the lungs. It can spread to the lungs and other organs and is usually fatal.  The mediastinal lymph nodes are located in the area between the lungs. When the body is fighting … Continue reading Minimally Invasive Lymph Node Staging May Prevent Unnecessary Mesothelioma Surgery »

Dendritic Cell Therapy for Mesothelioma: Can it Help Other Treatments Work Better?

dendritic cell therapy for mesothelioma

A new kind of mesothelioma treatment called dendritic cell therapy might make other types of treatments even more effective.  Right now, chemotherapy with Alimta (pemetrexed) is the only approved therapy for malignant mesothelioma. Many others are in the works. But so far, none of them extend the lives of mesothelioma patients by more than a few months.  Dendritic cell therapy for mesothelioma may be different. This novel treatment uses the patient’s own cells to jumpstart the immune system.  A Dutch company developed and is testing the new treatment. The data so far suggests that it could boost chemotherapy and help new drugs like Keytruda work better.  How Dendritic Cell Therapy Works Dendritic cells are immune system cells that function as … Continue reading Dendritic Cell Therapy for Mesothelioma: Can it Help Other Treatments Work Better? »

New Cancer Blood Test Could Identify Early Mesothelioma

cancer blood test

Israeli researchers hope that a new kind of cancer blood test could help detect mesothelioma and other malignancies earlier. Earlier diagnosis could lead to longer mesothelioma survival. The blood test is based on the idea that immune system cells undergo metabolic changes when they fight a cancer like pleural mesothelioma. Different kinds of changes are associated with different kinds of cancers. The new cancer blood test detects these changes. Immune System Cells and Metabolism The immune system is the body’s primary way of defending itself against diseases like malignant mesothelioma. Metabolism refers to the way immune system cells expend energy to fight cancer.  An Israeli company is developing the new cancer blood test. It focuses on the metabolism of immune … Continue reading New Cancer Blood Test Could Identify Early Mesothelioma »

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