Understanding Mesothelioma Diagnosis Through Fluid Samples

Understanding Mesothelioma Diagnosis Through Fluid Samples

Diagnosing mesothelioma, a cancer caused by asbestos exposure, can be challenging. One method used is serous fluid cytology (SFC). SFC involves examining fluid samples for cancer cells. But, distinguishing between reactive cells and cancerous cells can be difficult. Ancillary Tests for Better Diagnosis To improve accuracy, doctors may use ancillary tests. These include BAP1 immunohistochemistry (IHC) and fluorescence in-situ hybridization (FISH) for CDKN2A deletion. These tests help identify specific markers that show the presence of cancer cells, making the diagnosis more reliable. A new article reviewed cases of SFC samples taken from patients suspected of having mesothelioma since 2012. Researchers found that out of 110 cases, 61 were confirmed to have mesothelioma based on SFC results. Most patients were male,…