Malignant Pleural Mesothelioma: Timeline and Analysis of 70 Cases

Malignant Pleural Mesothelioma: Timeline and Analysis of 70 Cases

ByHolly Zink

Malignant pleural mesothelioma is a severe cancer linked to asbestos exposure. It often appears decades after exposure. The disease’s early symptoms are unclear, making it hard to diagnose early. Despite being rare, this cancer is a major health concern. It has a poor prognosis and few treatment options. A new article details the study of 70 cases at Getafe University Hospital from 2008 to 2021. Study Overview The study aimed to detail key aspects of malignant pleural mesothelioma. It covered clinical, histological, radiological, and treatment features. The hospital’s Ethics and Research Committee approved it. The sample involved 70 patients, mainly elderly males with an average age of 71. Asbestos exposure was found in 61% of cases. Common symptoms were shortness…

Malignant Pleural Mesothelioma: Pleural Decortication and Multimodal Therapy

Malignant Pleural Mesothelioma: Pleural Decortication and Multimodal Therapy

ByHolly Zink

Malignant pleural mesothelioma is a severe cancer caused by asbestos exposure. It impacts the lungs’ lining. Treating it is tough, as it’s aggressive and often diagnosed late. However, new surgical and therapy methods are offering hope. A recent article looks at pleural decortication, a crucial surgery, and how multimodal therapy helps. What is Pleural Decortication? Pleural decortication is a surgery that removes tumors and tough lung and chest wall tissue. It’s crucial in EPD, which treats mesothelioma. First, the surgeon removes the tumor and pleura. This allows the lung to expand fully. The surgery is methodical and exact. It ensures full tumor removal with minimal damage. Skilled thoracic surgeons in specialized centers usually perform this complex surgery. Hyperthermic Intrathoracic Chemotherapy…

Understanding Pleural Mesothelioma: A Rare and Aggressive Cancer
|

Understanding Pleural Mesothelioma: A Rare and Aggressive Cancer

ByHolly Zink

Pleural mesothelioma is a type of cancer that develops in the lining of the lungs, caused by exposure to asbestos. Despite being rare, pleural mesothelioma is aggressive and challenging to treat. A new article provides an overview of pleural mesothelioma, including its causes, symptoms, diagnosis, and treatment options. Causes, Symptoms, Diagnosis, and Treatment Exposure to asbestos is the primary cause of pleural mesothelioma. Asbestos fibers, when inhaled, can become lodged in the lungs, leading to inflammation and scarring of the pleura. Other risk factors for pleural mesothelioma include genetic predisposition and certain infections. Asbestos exposure remains the most significant risk factor. Symptoms of pleural mesothelioma can be nonspecific and may include chest pain, shortness of breath, and coughing. But, these…

Understanding Malignant Pleural Mesothelioma: What You Need to Know
| |

Understanding Malignant Pleural Mesothelioma: What You Need to Know

ByHolly Zink

Malignant pleural mesothelioma is a rare cancer caused by asbestos. It starts in the lining of the lungs and can cause symptoms similar to tuberculosis. A new article published in Respiratory Medicine provides a modern, comprehensive clinical overview of malignant pleural mesothelioma. The article provides an in-depth summary of everything you need to know. Navigating Malignant Pleural Mesothelioma Malignant pleural mesothelioma is not very common. In fact, only around 30,000 new cases were reported worldwide in 2020. This kind of cancer tends to affect older patients more, especially those over 40, and is more common in men. Malignant pleural mesothelioma is caused by exposure to asbestos, a material used in old buildings. The way malignant pleural mesothelioma grows in the…

Uncovering the Secrets of Long-Term Survival in Pleural Mesothelioma: The DNA Repair Factor

Uncovering the Secrets of Long-Term Survival in Pleural Mesothelioma: The DNA Repair Factor

ByHolly Zink

DNA repair plays an important role in a type of cancer called malignant pleural mesothelioma. Scientists have found that mesothelioma patients who live for a very long time do not have active DNA repair function. Exploring Longevity in Malignant Pleural Mesothelioma Mesothelioma is a type of cancer that develops from the thin layer of tissue that covers many of the body’s internal organs. Pleural mesothelioma grows in the lining of the lungs. There are about 2,000 cases of pleural mesothelioma each year in the United States. Mesothelioma is caused by exposure to asbestos. This is a toxic material that has been used in construction, manufacturing, and many other applications. This type of cancer is hard to treat, and doctors often…

Identifying Mesothelioma: How Extracellular Vesicles Could Be the Key
|

Identifying Mesothelioma: How Extracellular Vesicles Could Be the Key

ByHolly Zink

Scientists believe that particles called extracellular vesicles could be used as biomarkers to identify malignant pleural mesothelioma (MPM). Malignant pleural mesothelioma is an aggressive and deadly cancer that affects the lining of the lungs and chest cavity. It is caused by exposure to asbestos, usually at work. It has a low survival rate, so it is important to find ways to diagnose it early. It is also important for doctors to be able to predict how it will develop in patients. How Mesothelioma is Diagnosed Mesothelioma is usually diagnosed after a person goes to a doctor because they are experiencing symptoms. For MPM, a person might feel shortness of breath due to fluid around the lung, chest pain, cough, and…

Predicting Outcomes for People with Malignant Pleural Mesothelioma
| |

Predicting Outcomes for People with Malignant Pleural Mesothelioma

ByHolly Zink

A new study has found that a prognostic score based on the activity of just two genes could be useful in predicting outcomes for people with malignant pleural mesothelioma (MPM). The study was published the journal Diagnostics and was conducted by scientists from Bulgaria. Early Detection is Key for Better Outcomes Malignant pleural mesothelioma is a rare type of cancer that affects the lining of the lungs and chest called the pleura. It usually happens when a person has been exposed to asbestos. This is a harmful mineral that can be used in buildings and other materials. When asbestos fibers are inhaled, they can get trapped in the pleura and over time, cause cancer to develop. The cancer cells in…

Treating Relapsed Malignant Pleural Mesothelioma
| |

Treating Relapsed Malignant Pleural Mesothelioma

ByHolly Zink

Researchers from China explored whether immunotherapy or chemotherapy was a better option as a second-line treatment for relapsed malignant pleural mesothelioma (MPM). There is currently no standard of care for malignant pleural mesothelioma (MPM) that comes back after initial treatment. Because of this, it can be hard for doctors to make good care decisions for MPM patients who relapse. Malignant Pleural Mesothelioma MPM is a rare but serious cancer that grows on the lining of the lungs. It is caused by exposure to a toxic substance called asbestos. A healthy pleura is thin and flexible and expands to accommodate the lungs during respiration. In a person with mesothelioma, this membrane becomes thick and stiff, constricting the lungs and causing shortness…

Rare Mesothelioma Disease Combination
| |

Rare Mesothelioma Disease Combination

ByHolly Zink

Doctors in Italy treated a patient who was diagnosed with both primary gastric Burkitt lymphoma (PGBL) and malignant pleural mesothelioma (MPM). This is a rare disease combination. The doctors in this case had a hard time reaching the correct diagnosis because the symptoms of these two cancers are very similar. The patient also did not have the usual risk factors for these cancers. For instance, the patient did not have any exposure to asbestos that might cause MPM. Two Rare Diseases MPM is a rare type of cancer that develops from the thin layer of tissue that covers the lungs and chest wall. Signs and symptoms may include shortness of breath due to fluid around the lung, chest pain, cough,…

Improving Survival in Malignant Pleural Mesothelioma
|

Improving Survival in Malignant Pleural Mesothelioma

ByHolly Zink

Surgery to remove cancer tissue can lead to improved survival for epithelioid malignant pleural mesothelioma (MPM). Patients with sarcomatoid or biphasic malignant pleural mesothelioma did not have the same results. This is the finding of a study that looked at patient data from the National Cancer Database. Worst Prognosis with Standard Therapies MPM is an aggressive cancer that develops in the lining of the lungs. It is caused by exposure to asbestos and is difficult to treat. There are three cell types for this type of cancer: epithelioid, sarcomatoid, and biphasic. About half of malignant mesotheliomas are epithelioid. This type tends to have better treatment outcomes. About 10% of mesotheliomas are sarcomatoid. This type generally has the worst prognosis with…