Mesothelioma Mimics Ovarian Cancer: Lessons from a Case Report
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Mesothelioma Mimics Ovarian Cancer: Lessons from a Case Report

Mesothelioma mimics ovarian cancer in a new report by Radiology Case Reports. Mesothelioma is a rare and very aggressive tumor of the peritoneum. Similar clinical and imaging presentations mean mesothelioma mimics ovarian cancer at times. Yet, a history of asbestosis exposure is key as the main risk factor for mesothelioma. Imaging plays a key role in getting the diagnosis correct. It narrows down the diagnosis possibilities. Ultrasound-guided biopsy with histological study can confirm a mesothelioma diagnosis. Case Report Misdiagnosis The Bangladesh National Institute of Oncology recently published a case report. A 42-year-old woman reported pelvic pain and progressive abdominal distension. An abdominal ultrasound revealed a high volume anechoic peritoneal effusion. Further investigation showed extensive peritoneal disease and bilateral ovarian tissue…

Bevacizumab: An Immune Therapy in Mesothelioma Treatment
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Bevacizumab: An Immune Therapy in Mesothelioma Treatment

Bevacizumab, an immune therapy, enhances the immune system to target cancer cells. Historically, chemotherapy drugs were considered the standard treatment. But, a new study highlights bevacizumab, an immune therapy. It can now be considered in combination with mesothelioma treatments where accessible. Chemotherapy has been a popular treatment therapy. Cytotoxic chemotherapy uses anti-cancer (cytotoxic) drugs to destroy cancer cells. It results in a modest improvement in patient survival. But toxicity limits the eligible patient population. Targeted Chemotherapy Agents Immunotherapies are now playing a greater role in the treatment of many cancers. The last decade has presented a paradigm shift. There has been a change in the way we understand the relationship between the immune system and cancer progression. Several targeted agents…

Mesothelioma Surveillance Protocols, Quality of Life, and Patient Hope
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Mesothelioma Surveillance Protocols, Quality of Life, and Patient Hope

Mesothelioma surveillance protocols are a series of medical tests. Surveillance is designed to detect and track cancer progression. Surveillance protocols also check treatment effectiveness. And they provide patients with reassurance and hope. A new study identified the effectiveness of mesothelioma surveillance protocols. This study focused on patients who have noncurative treatment intent. Importance of Reassurance and Hope Findings from nine different studies identified the need for reassurance and hope as part of surveillance. They also highlighted the importance of trust and relationships. Follow-up and surveillance models provide patients with continuity, reassurance, and updates on condition. Continuity ensured patients knew who to contact if they had a new symptom or concern. Patient hopes for follow-up were for management of pain and…

Research Advancements Audit by Asbestos Diseases Research Institute
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Research Advancements Audit by Asbestos Diseases Research Institute

Research advancements provide a brighter future for malignant pleural mesothelioma patients. Pleural mesothelioma is an aggressive cancer of the lung lining. Mesothelioma is associated with asbestos exposure. Australian researchers from the Asbestos Diseases Research Institute and the University of Sydney have reviewed the basic research advancements. Their new publication covers mesothelioma biomarkers and treatment strategies. There is a long latency period from asbestos exposure to cancer development. A lack of genetic biomarkers makes early diagnosis difficult. The prognosis of pleural mesothelioma is poor. There is an average survival of eight to fourteen months following diagnosis. Diagnostic Biomarkers Biomarkers are limited in the clinic to diagnose pleural mesothelioma. A biomarker is a biological molecule found in blood or other body fluids…

A Multimodality Treatment Plan may be Best for Pleural Mesothelioma
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A Multimodality Treatment Plan may be Best for Pleural Mesothelioma

A multimodality treatment plan may improve mesothelioma patient outcomes. Malignant pleural mesothelioma is an invasive, locally aggressive tumor related to asbestos exposure. A new study shows that the best treatment plan for pleural mesothelioma may be when different types of therapy work together. The ideal combination of treatment therapies is still unknown. But a recent study encourages further studies on a multimodality treatment plan. This may include chemotherapy, surgery, and adjuvant radiotherapy. Current Clinical Guidelines: A History of Single or Multimodality Treatment Plans Despite a long history of clinical research, there is still no cure or any evidence of the best treatment. Many single-treatment plans, single-modality plans, have had disappointing results. Researchers have begun to evaluate different multi-modal treatment approaches….

Cells Talking in the Tumor Microenvironment: Cracking the Code
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Cells Talking in the Tumor Microenvironment: Cracking the Code

The tumor microenvironment and stroma cells affect the progression and treatment of malignant pleural mesothelioma. A new study shows how cells support the malignancy of mesothelioma and potential therapies. Malignant pleural mesothelioma has a unique and complex tumor microenvironment. A new study recently showed that the tumor microenvironment plays a key role in cancer initiation and progression. Scientists are seeking to understand how cancer and non-cancer cells communicate. Cancer and Non-Cancer Cells Talk to Each Other When white blood cells do not filter out asbestos fibers, other cells in the body are able to begin growing cancerous mesothelial cells. Scientists are seeking to understand how cancer and non-cancer cells communicate in the body. Non-cancer cells include immune cells and stromal…

Detecting Mesothelioma by Smell: A Promising Future
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Detecting Mesothelioma by Smell: A Promising Future

Early cancer detection can be difficult, but there is a promising history of research on detecting mesothelioma by smell. A new study suggests that a change in a patient’s body odor may be used for early malignant pleural mesothelioma detection. This holds tremendous hope for early treatment. Right now, pleural mesothelioma detection relies heavily on various clinical tests. These tests often include radiography, CT, MRI, ultrasound, and biopsy. All of these technologies and methods are effective. However, several are invasive, expensive, time-consuming, or limited to large hospital settings. In an article in BBA – Reviews on Cancer, researchers explore how body odor can detect malignant pleural mesothelioma. The team says the research on detecting mesothelioma by smell is promising. Nevertheless,…