A mutation of the BAP1 gene may not be the only reason mesothelioma can sometimes run in families. A more complex genetic picture may also help explain why some asbestos-exposed workers get the disease and some do not. Exposure to asbestos is the number one cause of malignant mesothelioma, an aggressive cancer that starts on the membranes that surround internal organs. But only a tiny percentage of people exposed to asbestos – many of whom were construction workers, asbestos plant employees, or veterans – ever contract mesothelioma. Past studies have explained the disparity, in part, by showing that a mutation on the BAP1 gene appears to make some people more susceptible to the damaging effects of asbestos. But a new … Continue reading Could Other Gene Mutations Be Behind Mesothelioma?
Victims of mesothelioma and their families are being invited to make their voices and their stories heard on social media in advance of the 11th annual Mesothelioma Awareness Day on September 26th. The invitation is being extended by the Asbestos Disease Awareness Organization (ADAO), an organization committed to ending the scourge of asbestos diseases like mesothelioma through education, advocacy and community. Founded in 2004, ADAO protects the rights of mesothelioma victims and others with asbestos diseases and works with public health organizations to prevent asbestos exposure. They have long called for the US Congress to enact an asbestos ban. “Currently in the United States, we are witnessing one of the most crucial moments in Toxic Chemical reform and … Continue reading Mesothelioma Awareness Day Gets a Boost from Social Media
Some Italian workers are paying a high price for Italy’s former position as the top European producer of asbestos. According to a new study in the American Journal of Industrial Medicine, both men and women who lived and worked in areas of heavy asbestos production are far more likely than their peers elsewhere in the country to contract peritoneal mesothelioma. Peritoneal mesothelioma is the rarer form of a very rare cancer. While the more common pleural mesothelioma occurs in the membranes around the lungs, peritoneal mesothelioma starts on the membrane that surrounds abdominal organs. Like all forms of mesothelioma, it is asbestos-related, hard to treat, aggressive, and usually lethal. To get an idea how prevalent peritoneal mesothelioma is in Italy … Continue reading Peritoneal Mesothelioma Rates Higher in Italy’s Asbestos-Producing Regions
Scientists have long known that mesothelioma, an aggressive cancer that affects the membrane around organs, is not the only cancer linked to asbestos exposure. Numerous studies have also found a link between asbestos and lung cancer. Now, a new study conducted in France and published in Occupational and Environmental Medicine suggests that, in addition to mesothelioma, asbestos-exposed workers also face a significantly higher risk of digestive cancers, including cancers of the esophagus, liver, colon and rectum. The study focused on a group of 2024 workers who worked in an asbestos plant in France between 1978 and 2009. Not surprisingly, people in the study faced a higher incidence of mesothelioma, a cancer that is extremely rare in the general public. But … Continue reading Beyond Mesothelioma: Asbestos Linked to Digestive Cancers
Targeted therapies may be the future of mesothelioma treatment. That word comes from a team of some of the world’s top mesothelioma researchers at the University of Hawaii and New York University. The group has just published a review detailing what is known about how mesothelioma develops – also called “pathogenesis” – and how that growing knowledge may help scientists develop more effective treatments. “Novel treatments are needed, as current treatment modalities may improve the quality of life, but have shown modest effects in improving overall survival,” writes Dr. Michele Carbone, corresponding author on the review and a top name in mesothelioma research. Dr. Harvey Pass, chief of the division of thoracic surgery at New York University’s Langone Medical Center … Continue reading Emerging Therapies Target Mesothelioma in New Ways