Mesothelioma Cell Growth Slowed with New Gene Therapy
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Mesothelioma Cell Growth Slowed with New Gene Therapy

There’s new evidence that therapies that prevent cancer cells from forming new blood vessels may offer a better way to approach malignant pleural mesothelioma. Mesothelioma is the most deadly of several diseases caused by asbestos exposure, including lung cancer, asbestosis and pleural plaques. Most people who develop mesothelioma live less than a year after diagnosis. It is most common in people who have lived or worked around asbestos. Although the disease is resistant to most conventional cancer therapies, a new report published by doctors at the Hyogo College of Medicine in Japan and the University of Miami suggests that agents that prevent blood vessel growth, known as angiogenesis, may be more effective. To test the theory, they introduced angiostatin, endostatin…

Spice May Trigger Mesothelioma Cell Breakdown
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Spice May Trigger Mesothelioma Cell Breakdown

There’s more evidence that cancer researchers might do well to spice up their mesothelioma clinical trials. A team of researchers at Keio University in Tokyo report that curcumin, the primary component in the spice turmeric, can effectively reduce the viability of human mesothelioma cells in the laboratory. This, despite the fact that mesothelioma is notoriously resistant to many types of conventional cancer therapies. “Curcumin, which has a long history as a dietary spice, is known to suppress the growth of multiple cancer lines, but the effects on mesothelioma cells are not well-defined,” observed principal investigator Y. Yamauchi in Phytotherapy Research. Mesothelioma is an aggressive cancer of internal membranes, triggered by asbestos exposure. Citing mesothelioma’s well-known treatment resistance, Yamauchi says alternative…