Second-Line Treatment for Mesothelioma with Lurbinectedin

second-line treatment for mesothelioma

Swiss researchers may have finally found an effective second-line treatment for mesothelioma.  Scientists with the Swiss Group for Clinical Cancer Research presented their findings at the recent European Society for Medical Oncology conference in Barcelona.  Mesothelioma patients who fail after first-line therapy have few options. The new study focused on lurbinectedin, a drug that impacts cancer cells at the DNA level. Early studies suggest lurbinectedin might make a good second-line treatment for small cell lung cancer.  According to the Swiss team, more than half of patients in their study responded to lurbinectedin as a second-line treatment for mesothelioma.  In Search of a Second-Line Mesothelioma Treatment Malignant mesothelioma is notoriously difficult to diagnose and even harder to treat. It is usually … Continue reading Second-Line Treatment for Mesothelioma with Lurbinectedin »

Peritoneal Mesothelioma Surgery with HIPEC Can Trigger Blood Cell Problems

peritoneal mesothelioma surgery with HIPEC

More than half of patients who have peritoneal mesothelioma surgery with HIPEC develop problems with their blood cells afterward. That’s the finding of a team of cancer researchers from Singapore.  The group analyzed 15 years worth of data on peritoneal mesothelioma surgery outcomes. They found that, even though the procedure saves lives, it can be risky.  Older patients and those who had prior chemotherapy were most likely to develop hematological toxicities after peritoneal mesothelioma surgery.  Hematological Toxicities and Mesothelioma Treatment Hematological toxicities are problems with the cells that make up the blood. This can include white blood cells, red blood cells, platelets, and proteins involved in bleeding and clotting.  Several drugs that kill mesothelioma cells can cause blood cell problems. … Continue reading Peritoneal Mesothelioma Surgery with HIPEC Can Trigger Blood Cell Problems »

CRISPR Gene Editing Technique and the Future of Mesothelioma Treatment

CRISPR gene editing tehcnique

The powerful CRISPR gene editing technique might have a role to play in the future of mesothelioma treatment. CRISPR is a method for altering certain genes to help fight disease. This week, scientists at the University of Pennsylvania released data from the first study of CRISPR in US cancer patients.  It was only a safety study, but the results are promising. They could have wide-ranging implications for patients fighting aggressive cancers like malignant mesothelioma.  Modifying Genes To Help Fight Cancer The CRISPR gene editing technique is a simplified version of the method bacteria cells use to defend themselves against viruses. This antiviral defense system is called CRISPR-Cas9. The new Penn Medicine study involved just three cancer patients. Two of the … Continue reading CRISPR Gene Editing Technique and the Future of Mesothelioma Treatment »

Mesothelioma Linked to Shipbuilding Finally Falling in the UK

mesothelioma linked to shipbuilding

After decades of higher-than-normal rates of mesothelioma near dockyards, cases of mesothelioma linked to shipbuilding appear to be falling in the UK. The UK has one of the highest per capita rates of malignant mesothelioma in the world. A big part of that comes from the shipbuilding industry where asbestos was used extensively. Now, a new report suggests the scourge of mesothelioma linked to shipbuilding is finally beginning to taper off, even though deaths from mesothelioma have not.  Why is Mesothelioma Linked to Shipbuilding? Asbestos is a naturally-occurring mineral that is strong and impervious to heat and corrosion. That made it a good insulator and a choice building material for many decades. Unfortunately, asbestos is also highly toxic.  Before scientists … Continue reading Mesothelioma Linked to Shipbuilding Finally Falling in the UK »

History of Asbestos Mining Blamed for Mesothelioma Epidemic

history of asbestos mining

Residents of Western Australia are still paying the price for the history of asbestos mining in the region. A new report from the University of Western Australia focuses on people in the region of the now-closed Wittenoom asbestos mine.  The report blames the mine and its products for an “ongoing epidemic of mortality from lung cancer and malignant mesothelioma”.  Australia’s Sad History of Asbestos Mining Asbestos is a mineral once prized for its strength and abundance. It was used around the world in thousands of products, including many construction materials.  Australia has a long history of asbestos mining and exportation. The country was once one of the world’s top producers of asbestos. The Australian Blue Asbestos Company in Wittenoom was … Continue reading History of Asbestos Mining Blamed for Mesothelioma Epidemic »

Supplement May Boost the Effectiveness of Mesothelioma Treatment

boost the effectiveness of mesothelioma treatment

A supplement that claims to increase oxygen in the tissues might boost the effectiveness of mesothelioma treatment.  That is the conclusion of researchers at Italy’s National Cancer Institute in Rome.  The group tested the supplement Cellfood (CF) on several types of cancer cells in the lab. They also gave the supplement to mice with implanted human mesothelioma tumors.  CF appeared to boost the effectiveness of mesothelioma treatment with radiation or chemoradiation.  What is Cellfood? Cellfood (Deutrosultazyme) is a nutraceutical produced by NuScience Corporation. A nutraceutical is a nutritional supplement that may function like a drug in some ways. According to NuScience, Cellfood contains colloidal minerals, amino acids, enzymes, and dissolved oxygen. Lab studies show that it has antioxidant effects and … Continue reading Supplement May Boost the Effectiveness of Mesothelioma Treatment »

Accurate Diagnosis of Pleural Mesothelioma with History and Imaging Only

accurate diagnosis of mesothelioma

Medical history and CT imaging may be enough to make an accurate diagnosis of pleural mesothelioma, even without a biopsy. That finding comes from a team of French and Canadian researchers led by Universite Laval in Quebec.  Biopsy is usually considered critical for accurate diagnosis of pleural mesothelioma. But the French and Canadian team says imaging studies may provide enough information to make a diagnosis.  This could be especially good news for people who are not healthy enough to undergo thoracoscopy. Pleural Mesothelioma Diagnostic Procedure: First Steps Pleural mesothelioma is the most common type of mesothelioma. Mesothelioma is an aggressive cancer that grows on the membranes around internal organs.  This cancer is rare and notoriously difficult to diagnose, especially in … Continue reading Accurate Diagnosis of Pleural Mesothelioma with History and Imaging Only »

Repeated Mesothelioma Surgeries Credited with Japanese Man’s Survival

repeated mesothelioma surgeries

Can repeated mesothelioma surgeries extend peritoneal mesothelioma survival? A new case report out of Japan suggests the answer may be yes.  The article recounts the case of a patient with peritoneal mesothelioma. Each time surgeons removed a mesothelioma tumor, a new one would occur in a different location.  The man had four separate mesothelioma surgeries over the course of five years.  Repeated mesothelioma surgeries are not the norm. But this treatment approach may be the reason for the man’s unusually long mesothelioma survival.  Surgical Treatment of Peritoneal Mesothelioma Peritoneal mesothelioma accounts for about 20 percent of mesothelioma cases in the US each year. It occurs on the membrane that surrounds the abdominal organs. Because it sits so close to these … Continue reading Repeated Mesothelioma Surgeries Credited with Japanese Man’s Survival »

Can Yogurt and Fiber Reduce Mesothelioma Risk?

reduce mesothelioma risk

The findings of a new lung cancer study suggest that eating yogurt and fiber might help reduce mesothelioma risk.  The study in JAMA Oncology involved more than 1.4 lung cancer patients from around the world.  Researchers assessed the results of 10 dietary studies between 2017 and 2019. They found a “synergistic association” between eating fiber and yogurt and a lower risk of lung cancer.  Pleural mesothelioma is a lung-related cancer with many of the same characteristics as lung cancer. It is possible that the same dietary habits might reduce mesothelioma risk, too.  The Yin and Yang of an Anti-Cancer Diet The lung cancer researchers did not choose to study yogurt and fiber randomly. Dietary fiber is the main source of … Continue reading Can Yogurt and Fiber Reduce Mesothelioma Risk? »

Pleural Mesothelioma Staging: These Overlooked Lymph Nodes Might Help

pleural mesothelioma staging

An often-ignored set of lymph nodes behind the ribs could help make pleural mesothelioma staging more accurate and valuable.  Staging is the process of determining how advanced a patient’s cancer is. It involves looking at various different factors and assigning a rating between 0 and 4. A higher stage indicates more extensive cancer. A new report suggests that the posterior intercostal lymph nodes behind the ribs play a more important role in pleural mesothelioma staging than previously thought. Mesothelioma patients with cancer in these nodes lived half as long as other mesothelioma patients.  Researchers in Maryland and Pennsylvania say removing and examining these nodes may lead to more accurate staging, more informed treatment decisions, and better outcomes.   How Lymph Nodes … Continue reading Pleural Mesothelioma Staging: These Overlooked Lymph Nodes Might Help »

Get your free copy of
“Surviving Mesothelioma” Today!