Tag Archives: chromosome 3p21

Genetic Mutation Improves Mesothelioma Survival Odds

Another new study has been released that supports the idea that mesothelioma patients who are missing the tumor suppressor called BAP1 are more likely to survive longer than those who have intact BAP1 genes. The BRCA-1-associated protein 1 (BAP1) gene is located on the chromosome 3p21. Because the job of BAP1 is to help suppress cancer, a mutation that causes this gene to be inactive raises the risk that a person could get mesothelioma or another cancer. BAP1 loss has also been associated with increased risk of skin cancer, renal cell cancer and some lung and breast cancers. But there appears to be an upside to BAP1 loss. Data published in the journal Pathology suggests that mesothelioma patients with BAP1 … Continue reading Genetic Mutation Improves Mesothelioma Survival Odds »