Tag Archives: fibulin-3

Mesothelioma Management: Different Biomarkers Serve Different Functions

Australian researchers have attempted to settle the debate about the value of the newly proposed mesothelioma biomarker fibulin-3 compared with the gold standard biomarker mesothelin.  According to their new report in the journal Thorax, mesothelin is still the best marker for diagnosing mesothelioma but fibulin-3 is better at predicting mesothelioma outcomes. The multi-center study included 153 patients – 82 with pleural mesothelioma, 36 with other types of malignancies causing pleural effusions (excess lung fluid), and 35 with benign effusions. For comparison, the team also measured biomarker levels in the blood plasma of 49 people with non-mesothelioma asbestos-related diseases. Researchers measured mesothelin and fibulin-3 levels in both pleural effusions and blood plasma and determined that mesothelin provides the best diagnostic accuracy, … Continue reading Mesothelioma Management: Different Biomarkers Serve Different Functions »