Tag Archives: treatment

New Mesothelioma Immunotherapy Treatment Reduces Tregs with Immunotoxin

mesothelioma immunotherapy treatment

There is a new mesothelioma immunotherapy treatment in the works. This one is based on reducing the number of Tregs or regulatory T-cells around a mesothelioma tumor. Tregs are an important part of maintaining balance in the immune system. They help protect people against autoimmune diseases like MS and lupus. But in people with malignant mesothelioma and other types of cancer, too many Tregs can be a problem. Tregs respond to distress signals sent out by a tumor. They surround the tumor and protect it against attack from the immune system. The goal of mesothelioma immunotherapy treatment is to reactivate the immune system to fight the cancer. Developing a Mesothelioma Immunotherapy Treatment Molecular biologists at the National Cancer Institute and … Continue reading New Mesothelioma Immunotherapy Treatment Reduces Tregs with Immunotoxin »

New Mesothelioma Drug Trial Begins

mesothelioma drug trial

A new mesothelioma drug trial is now underway. The trial will test a brand new type of immunotherapy medication called CA-170. CA-170 is designed to block an immune system suppressor called VISTA. It is the only VISTA-blocking medication currently in clinical trial. “CA-170 has demonstrated favorable safety and tolerability as well as preliminary anti-tumor activity in patients across multiple tumor types,” the company said in a statement. Mesothelioma Drug Trial Focuses on VISTA Malignant mesothelioma is highly resistant to standard cancer treatments. Many top researchers believe that immunotherapy drugs offer the best promise for curing mesothelioma. That is because cancers like malignant mesothelioma survive in part by evading detection by the immune system. They do this in a variety ways … Continue reading New Mesothelioma Drug Trial Begins »

Doctor Attitude Keeps Some Patient from Mesothelioma Chemotherapy

chemotherapy for mesothelioma

A new study suggests that some patients are missing out on chemotherapy for mesothelioma because their doctors do not believe it will work. Doctor “nihilism” – the idea that life is meaningless anyway – was the top reason that 20+ percent of pleural mesothelioma patients did not get the care that might have helped them. In other cases, patients were simply never referred to a cancer doctor who could prescribe chemotherapy for mesothelioma. Doctor Attitudes and Chemotherapy for Mesothelioma The Australian study is based on surveys with 107 doctors and 19 nurses. Most respondents were either lung specialists or cancer doctors. They completed the surveys in 2014. The surveys show that most of the doctors (90%) think at least one … Continue reading Doctor Attitude Keeps Some Patient from Mesothelioma Chemotherapy »

Combination Therapy with Mesothelioma Surgery Leads to Longer Survival

Mesothelioma surgery patient with nurse

A new study finds almost a quarter of people who had combination therapy with mesothelioma surgery were still alive five years later. The study was published in the European Journal of Cardio-Thoracic Surgery. Researchers at University Hospitals KU Leuven in Belgium studied nearly 200 mesothelioma patients from 2003 to 2014. Many people do not live beyond about 18 months after a mesothelioma diagnosis. But the Belgian team says, for the right patients, there is a way to improve the odds. They say combination therapy with radical mesothelioma surgery offers a 1 in 4 chance of surviving for 5 years or more. Two Types of Mesothelioma Surgery There are two major schools of thought about mesothelioma surgery. Some surgeons say it … Continue reading Combination Therapy with Mesothelioma Surgery Leads to Longer Survival »

Best Tools for Measuring Mesothelioma Treatment Response

PET Scan

When it comes to evaluating treatment response in mesothelioma, functional imaging techniques may do a better job than standard imaging. That is the word from a team of UK researchers who compared different types of imaging techniques in the evaluation of pleural mesothelioma patients for an article in the journal Lung Cancer. Imaging Techniques for Mesothelioma Tumors Functional imaging, which includes techniques like positron emission tomography (PET), dynamic contrast-enhanced MRI, and diffusion-weighted MRI, are designed to tell doctors more than just the size or shape of the mesothelioma tumor. By using certain kinds of injectable tracers, these imaging studies reveal important information about cellular processes like metabolism, which is typically higher in mesothelioma cells than it is in normal cells. “By … Continue reading Best Tools for Measuring Mesothelioma Treatment Response »