Treatment Details – 7.0 months

Survival: 7.0 months
   
Toxicity Grade: 5
   
Treatments: Chemotherapy
   
Drugs: IFEX
Country: United States
   
City/State/Province: New York, New York
   
Hospital: Columbia University
   
Journal: Link
   
Date: 7/2003

Description:
Patients: This study involved 38 patients with malignant mesothelioma. Thirty-four had malignant pleural mesothelioma and four had malignant peritoneal mesothelioma.

Treatment: The treatment consisted of the chemotherapy drug ifosfamide (IFEX). (In addition, two other drugs were administered – mesna for chemoprotection and G-CSF to increase neutrophil count.)

Toxicity: There was one treatment-related death from infection, pulmonary edema, and renal failure. Grade 3-4 toxicities included hematologic, cardiovascular, circulatory, dermatologic, flu-like symptoms, gastrointestinal, infection, neurologic, neuromotor, neurosensory, pain, and pulmonary.

Results: The median overall survival was 7 months.
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