| Survival: | 7.0 months |
| Toxicity Grade: | 5 |
| Treatments: | Chemotherapy |
| Drugs: | IFEX |
| Country: | United States |
| City/State/Province: | New York, New York |
| Hospital: | Columbia University |
| Journal: | Link |
| Date: | 7/2003 |
| Description: |
| Patients: This study involved 38 patients with malignant mesothelioma. Thirty-four had malignant pleural mesothelioma and four had malignant peritoneal mesothelioma. Treatment: The treatment consisted of the chemotherapy drug ifosfamide (IFEX). (In addition, two other drugs were administered – mesna for chemoprotection and G-CSF to increase neutrophil count. Toxicity: There was one treatment-related death from infection, pulmonary edema, and renal failure. Grade 3-4 toxicities included hematologic, cardiovascular, circulatory, dermatologic, flu-like symptoms, gastrointestinal, infection, neurologic, neuromotor, neurosensory, pain, and pulmonary. Results: The median overall survival was 7 months. |