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Japanese Discovery Could Lead to New Mesothelioma Blood Test

mesothelioma blood test

A discovery in Japan could lead to a more effective mesothelioma blood test for mesothelioma diagnosis. Japanese scientists say they have found a better way to detect mesothelioma cells in the blood.  The scientists are experts in occupational health. Malignant mesothelioma is an occupational cancer because people can get it from working near asbestos. Mesothelioma diagnosis is challenging. But a powerful mesothelioma blood test could make it easier to find the asbestos cancer earlier. Treatment often works better when patients start it earlier. Circulating Tumor Cells in the Blood of Mesothelioma Patients No matter what kind of cancer a person has, their tumor releases some cells into the blood. Mesothelioma tumors are no exception. These circulating tumor cells (CTCs) are … Continue reading Japanese Discovery Could Lead to New Mesothelioma Blood Test »

In Search of a Better Mesothelioma Blood Test

A team from the Center of Molecular Medicine in Bochum, Germany tested the blood of 43 male mesothelioma patients along with 52 control subjects that had been exposed to asbestos but hadn’t developed mesothelioma. Blood was analyzed for the presence of mesothelin, a protein that is the most common blood-based mesothelioma biomarker, and miR-103a-3p, a microRNA gene. When the team attempted to identify the mesothelioma patients by mesothelin levels alone, they were able to correctly identify 74% of the sick patients. At the same time, the mesothelin-only blood test correctly ruled out mesothelioma in 85% of the healthy control subjects. The micro RNA gene proved to be a more accurate identifier of mesothelioma. Using the microRNA gene as their only … Continue reading In Search of a Better Mesothelioma Blood Test »

Mesothelioma Blood Test May Save Lives through Earlier Diagnosis

There is new evidence that a blood test for a biomarker called N-ERC/mesothelin could help identify mesothelioma earlier and improve outcomes in people at risk for the disease. Cancer researchers with Juntendo University in Tokyo released a study in 2008 suggesting that N-ERC/mesothelin, a soluble protein released by certain kinds of cancer cells, was “a very promising tumor marker for mesothelioma, especially epithelioid mesothelioma”. In their newest study, the same group attempted to test the value of the biomarker as a warning tool for closer monitoring in populations at high mesothelioma risk. The new study included construction workers who were part of a large-scale, 5-year screening of people known to be exposed to asbestos, the primary cause of mesothelioma. The … Continue reading Mesothelioma Blood Test May Save Lives through Earlier Diagnosis »

Mesothelioma Blood Test May Be Possible

An international team of researchers is studying the proteins found on the surface of cancer cells in an effort to improve mesothelioma diagnosis. The team, made up of scientists from the US, Switzerland, Italy and Chile, has just published their findings on a new kind of test to identify protein-derived mesothelioma biomarkers in blood serum. Mesothelioma is an aggressive cancer of the membranes around organs. Because the most common mesothelioma biomarker, mesothelin, is also overproduced by other kinds of cancer cells, it has only limited diagnostic value. A test to identify a set of proteins produced specifically by mesothelioma cells could greatly improve diagnostic accuracy. Led by Ferdinando Cerciello and Bernd Wollscheid of the Institute of Molecular Systems Biology in … Continue reading Mesothelioma Blood Test May Be Possible »

New Blood Test May Help Diagnose Mesothelioma Earlier

Investigators in California are evaluating new technology that could eventually help diagnose mesothelioma with a simple blood test. Mesothelioma is a rare cancer caused by exposure to asbestos.  It strikes about 2,500 people in the U.S. each year.  But its rarity – and its tendency to mimic other lung-related diseases – can make mesothelioma hard to diagnose.  In recent years, some mesothelioma centers have begun evaluating the DNA composition of suspected mesothelioma cells using a test called a DNA array. Now, a group of researchers in California reports that a different type of evaluation – one that looks for abnormal sugars (glycans) in blood serum – may offer another diagnostic option for mesothelioma.  Anti-glycan antibodies are produced by the immune system … Continue reading New Blood Test May Help Diagnose Mesothelioma Earlier »