Tag Archives: breast cancer

Mesothelioma Growth Slowed by Breast Cancer Drug

A drug most often associated with the treatment and prevention of breast cancer may offer a new way to treat pleural mesothelioma, too. A new study conducted by Ireland’s Royal College of Surgeons and published in the medical journal Anticancer Research focuses on tamoxifen as a novel mesothelioma therapy. How Tamoxifen Works Tamoxifen helps fight breast cancer and protect high-risk women from getting it by blocking cancer cells from using the estrogen they need to grow. Given that some types of mesothelioma tumors also appear to rely on estrogen to fuel their growth, the Irish scientists theorized that a drug like tamoxifen, which modulates estrogen receptors, could be used to enhance mesothelioma therapy. Testing Tamoxifen on Mesothelioma Cells The researchers … Continue reading Mesothelioma Growth Slowed by Breast Cancer Drug »

When “Breast Cancer” is Actually Mesothelioma

A new case study out of Italy highlights the importance of using all of the available tools – including patient history – to distinguish mesothelioma from other types of cancer. Oncologists in the Ob/Gyn department at Umberto I Hospital in Rome have just published the details of a female patient who was originally believed to have breast cancer. The 49-year-old hairdresser was found to have a hard lump, about 3 centimeters in diameter, lying against the lowest layers of her right breast. But when her doctors performed a biopsy and tested the cells, they discovered that the lump was not what they thought it was. “Estrogen receptors and progesterone receptors were negative,” writes Dr. Marialuisa Framarino-Dei-Malatesta, the paper’s lead author. … Continue reading When “Breast Cancer” is Actually Mesothelioma »

‘Breast Cancer Gene’ May Impact Mesothelioma Treatment

A gene most often associated with breast cancer may also play a vital role in the effectiveness of mesothelioma treatment. BRCA1 has been shown to be closely linked to the risk of breast cancer and a number of other malignancies. But a new study out of Ireland suggests that there may also be a connection between BRCA1 expression and sensitivity to vinorelbine, an antimitotic chemotherapy drug, in mesothelioma tumors. Classified as a plant alkaloid, vinorelbine attacks tumor cells by interfering with their ability to properly divide the chromosomes in their nuclei (mitosis). To test the connection between BRCA1 and vinorelbine sensitivity in mesothelioma, the researchers tested 144 mesothelioma tissue specimens for their level of BRCA1 expression.  They found that 38.9% of … Continue reading ‘Breast Cancer Gene’ May Impact Mesothelioma Treatment »