Tag Archives: diagnose mesothelioma

Diagnosing Mesothelioma with DNA in Cancerous Cells

Diagnosing Mesothelioma with DNA in Cancerous Cells

DNA methylation could be used to diagnose mesothelioma earlier for better treatment outcomes. This is the finding of a study from a team of researchers from Belgium. The researchers analyzed 63 studies that looked at DNA methylation in mesothelioma. Mesothelioma is a type of cancer that is caused by exposure to asbestos. The cancer develops on the thin layer of tissue that covers the lungs and chest wall. Mesothelioma is usually diagnosed after a person goes to a doctor because they are experiencing symptoms. These symptoms depend on the type of mesothelioma. Pleural mesothelioma in the lungs may cause shortness of breath, pain in chest, and fluid retention. Peritoneal mesothelioma in the abdomen can cause abdominal pain, fatigue, and ascites. … Continue reading Diagnosing Mesothelioma with DNA in Cancerous Cells »

Understanding Sarcomatoid Mesothelioma

Understanding Sarcomatoid Mesothelioma

Mesothelioma is a cancer that is difficult to diagnose and treat. Sarcomatoid mesothelioma is the most aggressive type of mesothelioma. It also looks different from other types of mesothelioma, making it even harder to diagnose and treat. The cause of mesothelioma is exposure to asbestos. It takes decades for symptoms of this cancer to appear, and the symptoms often look like other diseases, like pneumonia. A proper diagnosis can take a long time, which means the cancer has more time to spread. Mesothelioma can be categorized into three groups: epithelioid, sarcomatoid, and biphasic. The type of mesothelioma a patient has depends on the shape of the cancer cells. Epithelioid mesothelioma has cube-shaped or column-shaped cells. Sarcomatoid mesothelioma has cells with … Continue reading Understanding Sarcomatoid Mesothelioma »

Needle Biopsy an Effective Alternative for Some Mesothelioma Patients

Mesothelioma patients who are not good candidates for thoracoscopy can still get a definitive diagnosis with a procedure called cutting-needle pleural biopsy. A team of Oxford-based scientists compared the two procedures to determine whether ultrasound-guided cutting needle biopsy could produce enough tissue to diagnose mesothelioma. Mesothelioma, an asbestos-linked malignancy that starts on the membrane around the lungs, can be difficult to diagnose. At the same time, because so many patients do not develop symptoms until the disease is in its later stages, rapid and accurate diagnosis is critical. Although patients suspected of having mesothelioma may undergo imaging tests, blood tests for tell-tale biomarkers, and pleural fluid analysis, tissue biopsy and examination of the cells remains the only way to obtain … Continue reading Needle Biopsy an Effective Alternative for Some Mesothelioma Patients »

New Biomarker May Detect Mesothelioma Earlier

Researchers at one of the country’s top cancer centers say they have found an effective way to diagnose mesothelioma earlier. Their findings are published in the latest issue of the prestigious New England Journal of Medicine. Fibulin-3 is a protein that is expressed in the membranes of blood vessels. A single mutation in the gene that encodes fibulin-3 has been implicated in a form of macular degeneration. Now, study author and professor of thoracic oncology Harvey Pass, MD, and his colleagues at New York University’s Langone Medical Center believe that fibulin-3 levels in the blood and pleural effusions (fluid around the lungs) can distinguish mesothelioma patients from those who have been exposed to asbestos but do not have the disease. It … Continue reading New Biomarker May Detect Mesothelioma Earlier »