Tag Archives: diagnosis

Mesothelioma in Women: Study Reveals Diagnostic Trends

mesothelioma in women

A major study of mesothelioma in women finds that women tend to contract the disease earlier in life than men do. The analysis included 354 cases of malignant mesothelioma from a database of more than 2,800.  While the average age for pleural mesothelioma diagnosis is 72, the average age for women to be diagnosed with any type of mesothelioma was just 60. It could mean that the latency period for mesothelioma is shorter for women than it is in men. It could also mean that women are more attuned to mesothelioma symptoms and recognize the disease sooner.  Mesothelioma’s Long Latency  The latency period is the time between exposure to a cancer-causing agent and the occurrence of cancer. Mesothelioma has one … Continue reading Mesothelioma in Women: Study Reveals Diagnostic Trends »

PET/CT for Mesothelioma Diagnosis: Age and Stage May Impact Accuracy

PET/CT for mesothelioma diagnosis

A new study of PET/CT for mesothelioma diagnosis shows that certain conditions can impact its accuracy. Test results may be less reliable in older patients and in those with very early stage mesothelioma.  The study comes from cancer researchers in Italy. They compared the accuracy of PET/CT for mesothelioma diagnosis in 141 patients over a 9-year period.  A third of the oldest patients with Stage 1 pleural mesothelioma received false negative results. The figure jumped to 40 percent when age was not considered.  What is PET/CT for Mesothelioma Diagnosis? Positron emission tomography (PET) and computed tomography (CT) are non-invasive methods of looking at internal tissues.  A CT scan takes X-rays from different angles. A computer compiles the images into a … Continue reading PET/CT for Mesothelioma Diagnosis: Age and Stage May Impact Accuracy »

Video-Assisted Pleural Biopsy for Mesothelioma is Not Always Accurate

video-assisted pleural biopsy

New research shows some patients are more likely to get an accurate mesothelioma diagnosis from video-assisted pleural biopsy than others.  Cancer doctors at Japan’s Hyogo College of Medicine conducted the new research. It included four hundred patients with suspected pleural mesothelioma.   The researchers found that certain conditions can affect the accuracy of video-assisted pleural biopsy. Patients with early stage mesothelioma, a lot of inflammation, or fibrous connective tissue around their tumors were more likely to be misdiagnosed. Biopsy for Mesothelioma Diagnosis VATS is the acronym for video-assisted thoracoscopic surgery. It is a minimally-invasive surgical technique to diagnose problems in the chest. Mesothelioma tumors grow on the membrane around the lungs (pleura). Doctors may use the video-assisted pleural biopsy technique … Continue reading Video-Assisted Pleural Biopsy for Mesothelioma is Not Always Accurate »

Uncertainly, Worry, and Hope Characterize the Experience of Mesothelioma

experience of mesothelioma

The experience of mesothelioma is characterized by uncertainty and worry for some patients. But the same patients say they are also optimistic and hopeful.  These findings come from in-depth interviews with seven people with pleural mesothelioma. They were all patients at Penn-Presbyterian Medical Center in Philadelphia.  This is not the first study on the lived experience of mesothelioma. But the authors say American mesothelioma patients are underrepresented in the medical literature. The US has a higher number of mesothelioma deaths each year than any other country.  The new study shows the experience of these patients is much like that of mesothelioma patients elsewhere in the world.  Fostering Understanding, Identifying Needs Mesothelioma is an extremely rare cancer with a poor prognosis. … Continue reading Uncertainly, Worry, and Hope Characterize the Experience of Mesothelioma »

Study Evaluates Breath Test to Detect Early Mesothelioma

detect early mesothelioma with breath test?

Doctors in Michigan have launched a study to determine if volatile organic compounds (VOCs) in exhaled breath can detect early mesothelioma. They are also looking for a correlation between participants’ VOCs and biomarkers in the blood. VOCs can give doctors vital information about cellular metabolism. Previous studies of VOCs show that they can sometimes indicate the presence of mesothelioma.  But no one knows yet if VOCs can really detect early mesothelioma. None of the previous studies have been big enough for the technique to be universally recommended.  How VOCs Can Detect Early Mesothelioma Cancer causes biochemical changes in the body. These biochemical changes produce VOCs that a person exhales. Different types of cancer produce different combinations of VOCs. Breath testing … Continue reading Study Evaluates Breath Test to Detect Early Mesothelioma »

Screening for Mesothelioma: New French Tool May Help

screening for mesothelioma

Researchers in France say they have come up with a highly accurate way of screening for mesothelioma and lung cancer.  A new study shows their method, which includes a job history, a questionnaire, and an in-person interview, is 100 percent accurate at identifying people with asbestos cancer. If it can be confirmed in a larger group of patients, the tool may allow for easier and earlier diagnostic screening for mesothelioma. The Challenge of Screening for Mesothelioma Malignant mesothelioma is a fast-growing cancer with a dismal prognosis. Earlier diagnosis might help, but the disease produces few symptoms until it is very advanced. By the time mesothelioma symptoms like chest pain and coughing appear, it is often too late for treatment to … Continue reading Screening for Mesothelioma: New French Tool May Help »

Accurate Diagnosis of Pleural Mesothelioma with History and Imaging Only

accurate diagnosis of mesothelioma

Medical history and CT imaging may be enough to make an accurate diagnosis of pleural mesothelioma, even without a biopsy. That finding comes from a team of French and Canadian researchers led by Universite Laval in Quebec.  Biopsy is usually considered critical for accurate diagnosis of pleural mesothelioma. But the French and Canadian team says imaging studies may provide enough information to make a diagnosis.  This could be especially good news for people who are not healthy enough to undergo thoracoscopy. Pleural Mesothelioma Diagnostic Procedure: First Steps Pleural mesothelioma is the most common type of mesothelioma. Mesothelioma is an aggressive cancer that grows on the membranes around internal organs.  This cancer is rare and notoriously difficult to diagnose, especially in … Continue reading Accurate Diagnosis of Pleural Mesothelioma with History and Imaging Only »

Machine Learning Tool May Predict Mesothelioma Survival Better Than Pathologists

machine learning tool

The developers of a machine learning tool called MesoNet say the program can predict mesothelioma survival better than a pathologist. MesoNet is a deep convolutional neural network. It analyzes digitized images of mesothelioma cells to predict overall survival. In a new article in Nature Medicine, its creators compared the machine learning tool with pathologist-read slides. Then they validated MesoNet with two different sets of mesothelioma patients.  The result may offer a new, more accurate approach to mesothelioma treatment planning.  What is a Machine Learning Tool? A machine learning tool is a computer program that gets “smarter” the more it runs. A deep convolutional neural network is a type of machine learning tool that analyzes images. The more images it analyzes, … Continue reading Machine Learning Tool May Predict Mesothelioma Survival Better Than Pathologists »

The Pathological Diagnosis of Mesothelioma: New Recommendations

pathological diagnosis of mesothelioma

An international team of researchers says it is time to refine the pathological diagnosis of mesothelioma. They are recommending a list of changes they say could make the process more effective. Mesothelioma is a deadly cancer caused by asbestos exposure. Under current pathology guidelines, it falls into just three categories. But the research team says those guidelines do not give doctors enough information. They recommend updates to make the pathological diagnosis of mesothelioma more specific.  Understanding Mesothelioma Pathology Pathologists study body tissue, fluids, and cells that are surgically removed. The pathological diagnosis of mesothelioma involves looking at cells under a microscope. Cells can then be put into a category.  About three quarters of mesothelioma cases are epithelioid. Epithelioid mesothelioma is … Continue reading The Pathological Diagnosis of Mesothelioma: New Recommendations »

Signs of Peritoneal Mesothelioma After Radiotherapy

signs of peritoneal mesothelioma after radiotherapy

Japanese researchers are reminding doctors to watch for signs of peritoneal mesothelioma in people who have undergone past radiotherapy.  Many cancer patients undergo radiotherapy. Radiation disrupts the DNA inside cancer cells. This can help keep these malignant cells from replicating and spreading.  But radiation treatment also has a downside. It can cause cellular changes in healthy cells, too. This can cause side effects right away, or decades later.  As more people have radiation and survive, scientists at the Shinshu University School of Medicine say more of them could develop radiation-related mesothelioma later in life. But the signs of peritoneal mesothelioma years after radiation are easy to miss. Peritoneal Mesothelioma Case Study The new report is based on the case of … Continue reading Signs of Peritoneal Mesothelioma After Radiotherapy »