Tag Archives: diagnosis

Recurrent Pleural Effusion Could Signal High Mesothelioma Risk

recurrent pleural effusion

The case of a Japanese woman with recurrent pleural effusion suggests the problem could be a precursor of malignant pleural mesothelioma. Pleural effusion is a build-up of fluid on the space between the layers of the membrane that surrounds the lungs. It is common with mesothelioma and some other cancers.  In the new case study, the patient had recurrent pleural effusion for 15 years before she developed mesothelioma in situ. This is the earliest stage of asbestos cancer, before it becomes invasive. Her doctors say patients with similar problems should be tested for BAP1 loss and other signs of mesothelioma in situ.  Understanding Recurrent Pleural Effusion Pleural effusion is a side effect of several conditions including heart disease and cancer. … Continue reading Recurrent Pleural Effusion Could Signal High Mesothelioma Risk »

The Best Biomarkers for Mesothelioma Diagnosis, Prognosis, & Monitoring

Best Biomarkers for Mesothelioma

What are the best biomarkers for mesothelioma? The answer is still Soluble Mesothelin-Related Proteins (SMRPs). That is the conclusion of a major review of medical literature by some of the world’s top mesothelioma experts. Dr. Harvey Pass of New York University’s Langone Medical Center and Dr. Michele Carbone of the University of Hawaii are among the authors on the new report.  They analyzed 20 years of research on the best biomarkers for mesothelioma. Several were valuable for mesothelioma prognosis. But SMRPs once again came out the winner for mesothelioma prognosis, diagnosis, and treatment monitoring.  How Do Biomarkers Work? A biomarker is any substance produced by the body that can act as a biological signpost. Proteins usually make the best biomarkers … Continue reading The Best Biomarkers for Mesothelioma Diagnosis, Prognosis, & Monitoring »

Lung Fluid Analysis Could Enhance Mesothelioma Survival, Report Finds

Lung Fluid Analysis

Swedish researchers say more people might survive mesothelioma if doctors paid more attention to lung fluid analysis in making their diagnosis. The only way to definitely diagnose mesothelioma is to examine cells under a microscope. But pathologists at Karolinska University Hospital in Stockholm say tissue biopsy happens too late.  Lung fluid starts to collect much earlier in the disease process. The Swedish team says lung fluid analysis (cytology) could give doctors an earlier indication of mesothelioma. That could lead to earlier diagnosis and better survival. Diagnosing Malignant Mesothelioma There are many signs of malignant mesothelioma. Coughing, chest pain, and shortness of breath are some of the most common. When these symptoms occur in someone who has worked around asbestos, that … Continue reading Lung Fluid Analysis Could Enhance Mesothelioma Survival, Report Finds »

Artificial Intelligence in Mesothelioma Diagnosis, Prognosis, and Treatment Planning

Artificial Intelligence

Two newly-published studies highlight some of the ways that artificial intelligence may help with the diagnosis and treatment of malignant mesothelioma.  The first study focuses on machine learning algorithms for mesothelioma diagnosis. Researchers used data from Turkey, which has a high rate of mesothelioma among families.  A separate study from New York’s Mount Sinai Medical Center demonstrates the role that artificial intelligence can play in planning mesothelioma radiotherapy. Both studies suggest that machine learning may be a valuable tool to help doctors tackle asbestos cancer.  How Does Machine Learning Work? Artificial intelligence refers to intelligence generated by a computer. Like people, computers have to “learn” before they can provide intelligent answers to medical questions.  In both of the new studies, … Continue reading Artificial Intelligence in Mesothelioma Diagnosis, Prognosis, and Treatment Planning »

Epithelioid Mesothelioma and Lung Cancer: Biomarker Shows Which is Which

epthelioid mesothelioma and lung cancer

Researchers from Hiroshima University say they have found a nearly foolproof way to tell the difference between epithelioid mesothelioma and lung cancer.  This is critical because the prognosis can be very different between the two. They are also treated differently.  But epithelioid mesothelioma and lung cancer are similar in many ways. They cause many of the same symptoms. Even their cells look similar under the microscope. This can make it hard for doctors to deliver an accurate and timely diagnosis.  If the new findings are right, the biomarker identified by the Hiroshima researchers could be a diagnostic gamechanger.  Lung Adenocarcinoma or Pleural Mesothelioma? At first glance, epithelioid mesothelioma and lung cancer seem to be very different. Mesothelioma makes up about … Continue reading Epithelioid Mesothelioma and Lung Cancer: Biomarker Shows Which is Which »

Breast Cancer and Mesothelioma: Case Study Illustrates Diagnostic Challenge

breast cancer and mesothelioma

A newly published Croatian case illustrates how challenging it can sometimes be to distinguish between breast cancer and mesothelioma. The case involves a 61-year-old woman with what appeared to be breast cancer. Further study revealed that what the woman actually had was pleural mesothelioma. The mesothelioma had spread to her breast.  Breast cancer and mesothelioma cells look similar under the microscope. But they are very different. The authors of the new report caution doctors against the “pitfall” of mistaking one for the other.  Breast Metastasis is Rare Pleural mesothelioma occurs on the membrane that surrounds the lungs. It is rare for mesothelioma to spread to the breast. The most common place for mesothelioma cells to spread is the lungs.  Women … Continue reading Breast Cancer and Mesothelioma: Case Study Illustrates Diagnostic Challenge »

Mesothelioma and Lung Cancer: These Biomarkers Can Tell the Difference

mesothelioma and lung cancer

Researchers in Canada say when it comes to distinguishing between mesothelioma and lung cancer, some proteins are more valuable than others.  The team has identified an especially important protein biomarker for mesothelioma. A biomarker is a compound in body fluid or tissue that can act as a signpost for disease.  Understanding the value of this particular protein as compared to other biomarkers may improve the testing process for mesothelioma. Pleural mesothelioma and lung cancer share many of the same characteristics. Both affect the lungs and both cause similar symptoms. But they are treated differently.  It is not always easy to tell these two cancers apart, even with high-level diagnostic tools. But the biomarker testing completed in Canada may make it … Continue reading Mesothelioma and Lung Cancer: These Biomarkers Can Tell the Difference »

Diagnostic CT Scan for Mesothelioma: More is Better

diagnostic ct scan

A new report out of the UK suggests that a thorough diagnostic CT scan for pleural mesothelioma should include images of the abdomen and pelvis, as well as the chest.  When a person goes to the doctor with early signs of malignant pleural mesothelioma, a CT scan of the chest is often the next step in making a diagnosis. CT scans create a 3-dimensional image of internal organs, making it easier to spot mesothelioma tumors.  But a research team led by the University of Bristol says a diagnostic CT scan that shows only the chest might miss mesothelioma tumors in other areas. How a Diagnostic CT Scan Works CT stands for computerized tomography. CT scanning is an advanced type of … Continue reading Diagnostic CT Scan for Mesothelioma: More is Better »

Exhaled Breath Analysis: Is it the Future of Mesothelioma Diagnosis?

exhaled breath analysis

A new report says there is much for the mesothelioma community to be excited about in the technology known as exhaled breath analysis.  Several studies suggest the method is as accurate at identifying mesothelioma as some more invasive tests.  Researchers at the University of Leuven in Belgium led the new study. They analyzed six other studies on exhaled breath analysis The goal was to see how accurate the method is for diagnosing mesothelioma and other asbestos diseases. The researchers conclude that things look good for exhaled breath analysis, but there is more to learn.  Searching for Signs of Mesothelioma Pleural mesothelioma is an aggressive lung-related cancer caused by exposure to asbestos. It can take decades to develop, but once it … Continue reading Exhaled Breath Analysis: Is it the Future of Mesothelioma Diagnosis? »

Mesothelioma in Women: Study Reveals Diagnostic Trends

mesothelioma in women

A major study of mesothelioma in women finds that women tend to contract the disease earlier in life than men do. The analysis included 354 cases of malignant mesothelioma from a database of more than 2,800.  While the average age for pleural mesothelioma diagnosis is 72, the average age for women to be diagnosed with any type of mesothelioma was just 60. It could mean that the latency period for mesothelioma is shorter for women than it is in men. It could also mean that women are more attuned to mesothelioma symptoms and recognize the disease sooner.  Mesothelioma’s Long Latency  The latency period is the time between exposure to a cancer-causing agent and the occurrence of cancer. Mesothelioma has one … Continue reading Mesothelioma in Women: Study Reveals Diagnostic Trends »