A New Test for Mesothelioma?
Malignant pleural mesothelioma, an aggressive cancer of the pleural membrane that encases the lungs, can be difficult to diagnose. Early symptoms of the disease can be vague and mimic other lung conditions. But the longer a patient goes without a firm diagnosis, the poorer the prognosis is likely to be since mesothelioma is resistant to many traditional therapies. In addition to considering the patient’s symptoms and history of asbestos exposure, doctors often rely on biomarkers – compounds found in the blood or lung fluid – to pinpoint mesothelioma. Now, a group of Danish scientists are investigating a new biomarker that may eventually allow for an earlier, more accurate, mesothelioma diagnosis. Methylthioadenosine phosphorylase (MTAP) is a key enzyme used to help cells…