fowlpox

An experimental treatment using a modified bird virus may hold promise for people with advanced malignant mesothelioma. Fowlpox is a viral infection that primarily affects chickens and turkeys. It is caused by an avipoxvirus from the Poxviridae family.  Recently, some of the world’s top mesothelioma researchers at the John A. Burns School of Medicine at the University of Hawaii used an altered form of the Fowlpox virus to successfully stimulate an anti-tumor immune response in mice with mesothelioma cancer. The treatment focused on a protein called survivin which is overexpressed by most human cancers, including mesothelioma, but rarely found in healthy tissues. In an effort to jump-start the immune systems of lab mice into targeting and attacking survivin-producing mesothelioma cells, the…