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New Compound Proves Effective Against Mesothelioma in Mice

Japanese researchers believe they have found a powerful new compound to fight the aggressive cancer –malignant pleural mesothelioma. The team at the National Institute of Advanced Industrial Science and Technology in Tokyo have had success using a novel therapeutic compound called JBIR-23 in mice. JBIR-23 is a natural compound first derived from the bacteria Streptomyces sp. AK-AB27 in 2008.  In laboratory test tube studies, its unique chemical structure appears to have a cytotoxic effect on mesothelioma cells and promote apoptosis (cell death). When the compound was tested on mice with mesothelioma, the effect was the same.  JBIR-23 appears to prevent the further growth of the tumor, without loss of weight or other observable side effects. The news is promising in light … Continue reading New Compound Proves Effective Against Mesothelioma in Mice »