New Protein ‘Mimic’ Kills Mesothelioma Cells in Lab Tests
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New Protein ‘Mimic’ Kills Mesothelioma Cells in Lab Tests

Scientists testing a novel compound on mesothelioma cells in the lab say it may have the power to not only trigger cellular death, but also to stop mesothelioma from growing and spreading. CFMs (CARP-1 Functional Mimetics) are a class of compounds that ‘mimic’ the action of a protein called Cell Cycle Regulatory Protein (CARP) 1. As the name implies, CARP-1 plays a key role in regulating the life cycle of cells, including telling cells when it is time to enter apoptosis or programmed cell death. Cancers like mesothelioma can result when cells fail to enter apoptosis on schedule, while new cells are being created at a faster rate. When mesothelioma cells were exposed to CFMs in the lab, not only…