Danish researchers say people with the epithelioid subtype of pleural mesothelioma tend to live longer than those with other subtypes, even if they don’t receive treatment. The study is the latest to confirm what prior research suggests: that epithelial mesothelioma is more survivable than other subtypes. In the newest report, mesothelioma patients with the epithelioid subtype lived longer, even when they were not good candidates for curative treatment. Mesothelioma Subtypes and Symptoms Pleural mesothelioma is a fast-growing cancer on the membrane around the lungs. Exposure to asbestos is the primary cause of mesothelioma. There are three main mesothelioma subtypes. They are the epithelioid subtype, the sarcomatoid subtype, and the biphasic subtype. Epithelioid mesothelioma is the most common subtype. Sarcomatoid is … Continue reading Epithelioid Subtype Leads to Longer Survival Regardless of Treatment
The World Health Organization will soon recognize mesothelioma in situ as a fourth mesothelioma subtype. The 2015 WHO classification of pleural mesothelioma includes three histological subtypes. Pathologists can tell the difference between the subtypes by looking at the cells under a microscope. Each subtype has a slightly different cell shape, growth pattern, and nuclear characteristics. The proposed fourth mesothelioma subtype is a very early form of mesothelioma. Previous studies suggest that it may be a precursor to invasive mesothelioma. If patients know they have it, they may have years to try to keep mesothelioma from developing. Differences Between the Subtypes Pleural mesothelioma is a very rare type of cancer. Only about 2,500 people in the US receive a mesothelioma diagnosis … Continue reading WHO to Recognize Fourth Mesothelioma Subtype
Researchers in the UK say a breath test for mesothelioma might be able to distinguish between mesothelioma subtypes. There are three major subtypes of mesothelioma. It is important to know which kind of person has. A patient’s subtype can impact their prognosis and even their mesothelioma treatment choice. Right now, the only way to tell the mesothelioma subtypes apart is to look at the cells under the microscope. But scientists at Sheffield Hallam University have identified volatile organic compounds (VOCs) in the rarest and the most common mesothelioma subtypes. These VOCs could be used to develop a mesothelioma breath test that could tell the subtypes apart. The Advantages of Breath Testing Breath testing is a way of measuring VOCs in … Continue reading Breath Test for Mesothelioma Might Identify Subtypes
A new study of PET scanning for mesothelioma prognosis shows how much radioactive tracer a tumor absorbs can predict survival. This is especially true in people with the epithelioid mesothelioma subtype. The study comes from the Sungkyunkwan University School of Medicine in Seoul, South Korea. Researchers studied the medical records of dozens of mesothelioma patients diagnosed between 2009 and 2018. They found that SUVmax, a key factor in PET scanning for mesothelioma, is directly related to mesothelioma survival. How PET Scanning Works Mesothelioma diagnosis is challenging. Pleural mesothelioma grows quickly on the membrane around the lungs. It is one of the rarest and deadliest cancers. Positron emission tomography (PET) combined with computed tomography (CT) can help with diagnosis. During a … Continue reading The Importance of Subtype in PET Scanning for Mesothelioma Prognosis
New research out of Pennsylvania suggested that not all people with metastatic mesothelioma will live longer with chemotherapy. Although chemotherapy is the primary treatment for malignant pleural mesothelioma, some types of metastatic mesothelioma appear to be less responsive than others. In some cases, the researchers say best supportive care may be a better option for preserving a patient’s quality of life. Three Mesothelioma Subtypes There are three histological subtypes of malignant pleural mesothelioma. The categories are based on how the cells look under a microscope. Cell type appears to influence how aggressive they are as metastatic mesothelioma. Cell type also factors into mesothelioma prognosis. Epithelioid mesothelioma is the most common cell type. Epithelioid cells tend to lack uniformity and may … Continue reading Metastatic Mesothelioma: Does Chemotherapy Work?