A combination of three powerful mesothelioma therapies could become a new first-line treatment for mesothelioma if an upcoming clinical trial is successful. The makers of the experimental immunotherapy drug ONCOS-102 announced the new clinical trial. It will enroll up to 100 mesothelioma patients from around the world. The trial will test ONCOS-102 along with Keytruda (pembrolizumab) and standard chemotherapy. Keytruda is an immune checkpoint inhibitor. Both ONCOS-102 and Keytruda have shown some promise when combined with mesothelioma chemotherapy. Targovax hopes that the triple therapy approach will produce an even more powerful first-line treatment for mesothelioma. Clinic Trial of ONCOS-102 A first-line treatment is a treatment for mesothelioma patients who have not yet had any other therapies. Most patients start with … Continue reading Triple Therapy May Become New First-Line Treatment for Mesothelioma
A new first-line mesothelioma treatment has moved a step closer to becoming reality. New data show that the immunotherapy drug ONCOS-102 continues to look promising, nine months into a Phase I/II clinical trial. The drug was especially helpful to mesothelioma patients who had not yet had any treatment. Norweigian drug maker Targovax made the announcement earlier this month. ONCOS-102 is an experimental drug based on a modified virus. The virus helps it target mesothelioma cells while leaving healthy cells alone. The latest results show ONCOS-102 helps standard mesothelioma chemotherapy work better. Targovax says the next step will be a larger test of the combination as a first-line mesothelioma treatment. Clinical Trial of ONCOS-102 The power of ONCOS-102 comes from the … Continue reading Could ONCOS-102 Be a New First-Line Mesothelioma Treatment?
Early results are in on the latest trial of immunotherapy with ONCOS-102 and the news is good for pleural mesothelioma patients. Norweigian drug maker Targovax released the news about ONCOS-102 earlier this week. The new drug is based on an oncolytic virus that targets mesothelioma cells. When the virus gets inside the cells, it triggers an immune response. Early tests of immunotherapy with ONCOS-102 showed it helped mesothelioma chemotherapy work better. Now, a larger study appears to confirm the effect. The news could lead to new and better treatments for this intractable cancer. What is an Oncolytic Virus? An oncolytic virus is a virus that targets cancer cells. ONCOS-102 was designed to seek out mesothelioma cells. It is made out … Continue reading Immunotherapy with ONCOS-102 Shows Promise for Mesothelioma