PIPAC May Make More Patients Candidates for Mesothelioma Surgery

candidates for mesothelioma surgery

Researchers in France have come up with a way to turn some people with inoperable peritoneal mesothelioma into good candidates for mesothelioma surgery.  They are using a new technique to spray chemotherapy drugs directly onto peritoneal tumors in order to shrink them.  In some cases, the technique shrunk mesothelioma tumors enough that they could be surgically removed with the CRS/HIPEC procedure.  What Makes a Good Candidate for Mesothelioma Surgery A number of factors influence whether patients are good candidates for mesothelioma surgery. Patients have to be in otherwise reasonably good health so that their body can handle the surgery. It is also critical that their mesothelioma not be so widespread in their abdomen that it would be impossible for surgeons … Continue reading PIPAC May Make More Patients Candidates for Mesothelioma Surgery »

Dog Research May Lead to Over-the-Counter Mesothelioma Test

over-the-counter mesothelioma test

A cancer research project involving dogs could eventually pave the way for an over-the-counter mesothelioma test.  Researchers in Florida recently published a study suggesting that dogs may be able to detect lung cancer with surprising accuracy. If they can determine which cancer biomarkers the dogs detect, they may be able to develop an over-the-counter mesothelioma test.  Can Dogs Smell Lung Cancer? The new study comes from the Florida campus of the Lake Erie College of Osteopathic Medicine (LECOM). Researchers there are working with a canine training and research firm called BioScentDX. According to LECOM, a dog’s sense of smell is at least 10,000 times stronger than a person’s. The research team chose Beagles for the tests because they are among … Continue reading Dog Research May Lead to Over-the-Counter Mesothelioma Test »

Treating Advanced Peritoneal Mesothelioma with Spray-On Oxaliplatin

advanced peritoneal mesothelioma

European doctors have tested a new spray-on cancer drug that could be another treatment option for people with advanced peritoneal mesothelioma. The drug is oxaliplatin. It is sold under the brand name Eloxatin. It is normally given by injection into a vein. But that can cause serious side effects, including stomach pain. A new study published in the European Journal of Surgical Oncology suggests there may be a more effective way to get the benefits of oxaliplatin. Researchers found that using it as a spray for advanced peritoneal mesothelioma extended survival with fewer side effects. PIPAC for Advanced Peritoneal Mesothelioma As Surviving Mesothelioma first reported last spring, pressurized intraperitoneal aerosol chemotherapy (PIPAC) is a new way to deliver cancer medicines. … Continue reading Treating Advanced Peritoneal Mesothelioma with Spray-On Oxaliplatin »

Eating to Beat Mesothelioma: New Study Sheds Light on Diet/Cancer Link

nutrition to beat mesothelioma

A new study on the link between diet and cancer contains important information for patients trying to beat mesothelioma. The study was conducted by researchers at Tufts University and published this week in JNCI Cancer Spectrum. It compares American diets and rates of several kinds of cancer in 2015. The goal was to determine how many cancer cases might be blamed on poor diet. Although the study did not focus on mesothelioma cancer, patients determined to beat mesothelioma would be wise to take note of the findings. Poor Nutrition Can Lead to Cancer The Tufts researchers estimated that more than 80,000 cases of cancer diagnosed in 2015 happened because of suboptimal diet. That is more than 5 percent of all … Continue reading Eating to Beat Mesothelioma: New Study Sheds Light on Diet/Cancer Link »

Ofev Shelved as a Treatment for Pleural Mesothelioma

Treatment for pleural mesothelioma

It is official – the VEGF inhibitor Ofev is out of the running as a treatment for pleural mesothelioma. Hopes had been high for this drug after initial results showed a survival advantage. For the last two years, Ofev (nintedanib) was the subject of a large, international clinical trial. But now the leaders of that trial have published their Phase III trial results in The Lancet: Respiratory Medicine. They show that Ofev did not extend survival and is not an effective treatment for pleural mesothelioma. Why Hopes Were High for Ofev Ofev is an oral medication that stops cancer cells from producing a protein called VEGF. VEGF promotes the growth of blood vessels that help mesothelioma tumors grow. VEGF may … Continue reading Ofev Shelved as a Treatment for Pleural Mesothelioma »

Machine Learning Could Lead to Earlier Mesothelioma Diagnosis

earlier mesothelioma diagnosis

A machine learning tool being developed by Google could lead to earlier mesothelioma diagnosis and better survival rates. That word comes from Google artificial intelligence experts who recently presented their research at a developer conference in California. Machine learning specialist Lily Peng told the gathering that advanced A.I. can detect lung cancers like mesothelioma before doctors can even see them. Earlier mesothelioma diagnosis would allow for earlier intervention which could mean longer survival for victims of one of the world’s deadliest cancers. Diagnosis Often Comes Too Late Mesothelioma is a form of lung cancer caused by asbestos exposure. It can take decades to develop, but It is usually fatal within 18 months of diagnosis. One reason is that earlier mesothelioma … Continue reading Machine Learning Could Lead to Earlier Mesothelioma Diagnosis »

Mesothelioma Quality of Life Improves After Surgery

mesothelioma quality of life

New research confirms that surgery followed by HIPEC improves mesothelioma quality of life for people with peritoneal disease. Every mesothelioma surgery carries risks and can cause serious side effects. These problems often have a negative impact on mesothelioma quality of life in the short term. But researchers at Wake Forest University say cytoreductive surgery followed by intraperitoneal chemotherapy (HIPEC) boosts life quality for most mesothelioma patients over time. Evolving Management of Peritoneal Mesothelioma Malignant mesothelioma is a fast-growing cancer with a very low cure rate. Peritoneal mesothelioma accounts for about a fifth of all mesothelioma cases. With peritoneal mesothelioma, tumors start on the membrane that surrounds the abdominal organs and can spread to other parts of the body. Fatigue, pain, … Continue reading Mesothelioma Quality of Life Improves After Surgery »

Many Elderly Mesothelioma Patients Get No Treatment

elderly mesothelioma patients

The majority of elderly mesothelioma patients are observed rather than treated and this can have a negative impact on their survival. That is the finding of a new study published in the Annals of Surgical Oncology. The study included more than 4,500 mesothelioma patients. Less than a quarter of these patients received any treatment for their mesothelioma. As a result, most of these patients lived less than six months. Treatment Options for Elderly Mesothelioma Patients Exposure to asbestos causes pleural mesothelioma. It can take decades after exposure for mesothelioma symptoms to occur. The median age for a malignant pleural mesothelioma diagnosis is 72. The older a patient is at diagnosis, the more likely they are to have other health problems. … Continue reading Many Elderly Mesothelioma Patients Get No Treatment »

Lower-Volume Centers Less Likely to Follow Mesothelioma Treatment Guidelines

mesothelioma treatment guidelines

Mesothelioma patients need to beware of low-volume centers that are less likely to follow mesothelioma treatment guidelines. That is the message from a new study based on data from the National Cancer Institute. The study was run by doctors at Cedars-Sinai Medical Center in Los Angeles. It shows that treatment centers that do not see a lot of mesothelioma cases are less likely to follow the life-saving mesothelioma treatment guidelines. As a result, patients treated in these lower-volume facilities tend to have shorter mesothelioma survival. What are the Mesothelioma Treatment Guidelines? Malignant pleural mesothelioma is a cancer that occurs on the membrane that surrounds the lungs. It is extremely rare and difficult to treat. Many hospitals and doctors never see … Continue reading Lower-Volume Centers Less Likely to Follow Mesothelioma Treatment Guidelines »

Combination Mesothelioma Therapy Begins Pivotal Trial

mesothelioma treatment combination

A combination mesothelioma therapy that showed promise in early trials is finally being studied on a larger scale. The power-packed chemo-immuno-gene therapy known as TR002 has the potential to change the outlook for thousands of malignant mesothelioma patients. A small trial of the combination mesothelioma therapy in 2016 produced “significantly higher” mesothelioma survival rates than most patients are told to expect. Drug company Trizell announced last month that the combination will now be tested on 300 patients at sites in the US, Europe, Australia and Russia. Combination Mesothelioma Therapy Starts with Gene Therapy TR002 is an investigational gene therapy for mesothelioma patients who have failed first-line chemotherapy. This combination mesothelioma therapy is based on the human interferon-alpha 2b gene. The … Continue reading Combination Mesothelioma Therapy Begins Pivotal Trial »

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