New National Cancer Institute research shows a cancer-fighting gel applied directly to the surface of a mesothelioma tumor could “change the treatment paradigm” for this troublesome cancer. NCI researchers in Maryland developed the treatment and tested it in animals with mesothelioma tumors. Their tests show mesothelioma tumors respond after just one application of the medication. The authors of a new report on the treatment say surgeons could use it to enhance mesothelioma surgery. They could even use the cancer-fighting gel on its own as a stand-alone therapy. The Challenge of Mesothelioma Tumor Shape Malignant mesothelioma is a surface malignancy. Surface malignancies are tumors that grow on the surface of other organs or tissues. In the case of mesothelioma, tumors occur … Continue reading Cancer-Fighting Gel Could “Change the Treatment Paradigm” for Mesothelioma
Three small studies suggest that dendritic cells may offer a new, more promising way to fight malignant pleural mesothelioma. Dendritic cells are immune system cells that function as messengers. They are supposed to signal T-cells to attack cancers like malignant mesothelioma. But mesothelioma cells can keep dendritic cells from doing their job. The result is that the number of activated T-cells around mesothelioma tumors stays low and the tumors keep growing. Now, Dutch researchers studying the problem say a vaccine made from dendritic cells may hold the answer. They analyzed the results of three small dendritic cell studies. These studies included a total of 29 mesothelioma patients. Some of the patients in these studies lived much longer than mesothelioma patients normally … Continue reading Treatment with Dendritic Cells Leads to Long-Term Mesothelioma Survival in Small Studies
The first patient has been treated in the trial of a new drug that might help people suffering from mesothelioma-related weight loss. The drug is a synthetic cannabinoid called ART27.13. A cannabinoid is a compound that acts on the CB1 and CB2 receptors of the endocannabinoid system. There are a number of cannabinoid drugs on the market. But several of them have significant side effects, including effects on the brain. Preclinical data on ART27.13 suggest that it may stimulate the appetite and counter mesothelioma-related weight loss with fewer unwanted side effects. The Cancer Appetite Recovery Study (CAReS) is a Phase I trial to test it in people. The Danger of Mesothelioma-Related Weight Loss Over 60 percent of late-stage cancer patients … Continue reading Mesothelioma-Related Weight Loss: Synthetic Cannabinoid Might Help
There is new evidence that compounds found in the seeds of the evening primrose plant have the potential to slow the growth and spread of mesothelioma. Researchers in Poland extracted key compounds from the seeds using alcohol. They applied the extract (EPE) to malignant pleural mesothelioma cells in the lab. Evening primrose extract seemed to have the biggest effect on the most invasive mesothelioma cells. The more EPE the researchers used, the greater the impact. The study suggests there may be a future role for evening primrose in mesothelioma therapy. What is Evening Primrose? The evening primrose is a plant with yellow flowers. Its seeds contain a range of polyphenols including ellagic acid, gallic acid, and catechin. Oil extracted from … Continue reading Evening Primrose Extract Acts on Invasive Mesothelioma Cells, Study Shows
A combination of a low-calorie, plant-based diet and high levels of Vitamin C might offer a new and less-toxic way to combat malignant mesothelioma. A report published in the journal Nature Communications says the combination delayed tumor progression in mouse models of colorectal cancer. In some mice, it even caused their tumors to shrink. The most-affected tumors had a genetic mutation found in about a quarter of human cancers, including some cases of mesothelioma. Mutations in the KRAS gene help mesothelioma resist standard cancer treatments. The study indicates that adding Vitamin C to a diet that mimics fasting might help doctors get around this mesothelioma defence mechanism. The Anti-Cancer Effects of Ascorbic Acid Vitamin C is also known as ascorbic … Continue reading High-Dose Vitamin C and a Fast-Like Diet Might Help Fight Mesothelioma
A new review of the potential benefits of propolis suggests that this antioxidant-rich bee product might be a worthwhile addition to the fight against mesothelioma. Bees produce propolis from the sap of evergreens. The research on this supplement is limited. There has never been a study on propolis and mesothelioma. But a new Taiwanese review concludes that there is enough evidence on the benefits of propolis in several other types of cancer to warrant further study. What is Propolis? Propolis is a sticky resin that bees produce to help protect their hives. It is made up of a combination of evergreen sap, bee saliva, and beeswax. Bees coat their hives with it. Many ancient civilizations believed in the health benefits … Continue reading Benefits of Propolis: Could Bee Product Help Fight Mesothelioma?
A man-made version of a traditional Chinese herb could be an alternative treatment for mesothelioma. Turkish researchers have published a new study on a drug called halofuginone. The study shows the drug has significant anticancer effects on mesothelioma cells. In an article in Cell Biology International, they explore how halofuginone affects mesothelioma and lung cancer cells. Mesothelioma Patients Need Another Treatment Option Mesothelioma is an asbestos-linked cancer that is hard to treat. Pleural mesothelioma is the most common type. Pleural mesothelioma grows quickly. It usually causes few symptoms until it is very advanced. Chemotherapy is the main treatment. When that stops working, many patients look for an alternative treatment for mesothelioma. Scientists are studying immunotherapy, new kinds of radiotherapy, and … Continue reading Herb-like Compound May Be Alternative Treatment for Mesothelioma
The company that developed tumor treating fields for mesothelioma says it is still making, supporting, and studying the device in spite of the global pandemic. Last month, Novocure even announced a new name for the electricity-based mesothelioma therapy. Tumor treating fields or the NovoTTF-100L System will now go by the brand name Optune Lua. “Optune Lua is easy to pronounce and remember, and should help patients, caregivers and providers ask for the treatment by name,” says Pritesh Shah, Novocure’s Chief Commercial Officer. Novocure says they are following all WHO and CDC recommendations to keep producing tumor treating fields for mesothelioma patients who need it. What is Optune Lua? Tumor treating fields for mesothelioma uses specific frequencies of electric fields to … Continue reading Tumor Treating Fields for Mesothelioma Still on Track Amidst COVID-19
The research on curcumin treatment for mesothelioma looks promising, but more hard science is needed before doctors can incorporate it into their treatment plans. That is the message from a new multi-center international review of studies on curcumin for mesothelioma. Curcumin is a phytochemical that gives the spice turmeric its distinctive yellow color. Phytochemicals are compounds produced by plants. Different phytochemicals help plants fight disease or protect themselves from other threats. The new review summarizes the research on curcumin treatment for mesothelioma. It suggests that this compound may one day be a standard part of treating this intractable cancer. What Do We Know About Curcumin? Practitioners of natural medicine have used the curcumin in turmeric to treat disease for hundreds … Continue reading Curcumin Treatment for Mesothelioma: Research is Encouraging
A recent study out of Australia suggests that compounds called zeolites might offer protection against the toxic effects of asbestos. Asbestos is the primary cause of malignant mesothelioma. Mesothelioma is a rare and aggressive cancer for which there is no cure. There is no way to remove asbestos from the body after a person has been exposed. But the new study suggests that zeolites might counteract some of the toxic effects of asbestos. If the impact can be validated in humans, it could one day change the outcomes for thousands of people at risk for mesothelioma. What Are the Toxic Effects of Asbestos? Asbestos is a naturally-occurring mineral made up of long microscopic fibers. The size and shape of these … Continue reading Can These Compounds Protect Against the Toxic Effects of Asbestos?